Tag:

treatment strategies

Functional neurological disorders
Modulation of conformational features and oligomerization of MMACHC by cobalamin variants: impact of the R161Q mutation in cblC disease

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Modulation of MMACHC Conformational Features Recent investigations into the MMACHC protein have revealed that its …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Relevance of Biomarkers The study underscores the pivotal role of biomarkers in the clinical …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Association between concomitant traumatic brain injury and unfavorable 1-year outcomes in patients with traumatic spinal cord injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation centered around the relationship between traumatic brain injury (TBI) and the …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenesis of Myasthenia Gravis Myasthenia Gravis (MG) is an autoimmune disorder characterized by weakness and …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenic Role of Inflammatory Proteins In recent studies, inflammatory proteins have emerged as key players …

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Functional neurological disorders
Correlation of Positive Signs of Functional Neurological Disorder With Headache Severity: A Prospective Cross-Sectional Study

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Background on Functional Neurological Disorder Functional Neurological Disorder (FND) is a complex and often misunderstood …

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Functional neurological disorders
The Incidence of Misdiagnosis in Patients with Ehlers-Danlos Syndrome

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Prevalence of Misdiagnosis in Ehlers-Danlos Syndrome Recent studies have illuminated a concerning trend regarding the …

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Functional neurological disorders
Silent but significant: Functional elucidation of a synonymous ATP7B mutation in Wilson’s disease pedigrees

by myneuronews June 25, 2025

by myneuronews June 25, 2025

Significance of Synonymous Mutations Synonymous mutations are often perceived as inconsequential because they do not …

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Functional neurological disorders
Treating a Case of Disgust-Based Contamination Obsessive-Compulsive Disorder Using a Functional Approach to Exposure and Response Prevention: A Case Study

by myneuronews June 25, 2025

by myneuronews June 25, 2025

Understanding Disgust-Based OCD Disgust-based obsessive-compulsive disorder (OCD) is a unique subtype that predominantly presents with …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Neural reward processing among children with conduct disorder and mild traumatic brain injury in the ABCD study
CONCLUSIONS: Increased left amygdala and hippocampus activation in children with conduct disorder and a history of mild traumatic brain injury may reflect robust encoding of emotionally charged reward experiences, potentially reinforcing memory-guided, reward-seeking behaviors.
The utility of psychological readiness scales in predicting return to sport: a systematic review
CONCLUSION: This review underscores the value of psychological readiness assessments as predictors of RTS outcomes. The findings support their clinical utility, while also highlighting the need for further research into injury-specific and objective measures to enhance assessment accuracy. This systematic review has been registered in PROSPERO (registration number: CRD42025642947).
Impact of adverse childhood experiences on concussion recovery: Findings from the Toronto concussion study
CONCLUSIONS: Exposure to ACEs may sensitize individuals to concussion symptom endorsement in the acute stages but do not appear to prolong recovery from concussion. These findings support that clinicians should be aware of the impact of childhood traumas on an individual's health and assist in tailoring and providing individualized treatment plans, education and resources post-concussion.
Assessing Pediatric Traumatic Brain Injury and Health-Related Quality of Life in Three Eastern European Countries
CONCLUSIONS: Even mild pediatric TBIs can negatively affect HRQoL, particularly in older children. Incorporating HRQoL measures into TBI registries in LMICs can support evidence-based care, guide targeted interventions, and inform health policy in resource-limited settings.
Mobile Health App for Adults with Persisting Postconcussion Symptoms: Development and Usability Study
CONCLUSIONS: We developed a research-based symptom mapping app for people with persisting postconcussion symptoms. The app received high usability ratings from both the user and clinician groups. The app is a feasible alternative to traditional symptom mapping methods, and it is safe to use for its intended purpose.