Tag:

treatment strategies

Traumatic brain injury
Development of the Common Cognitive Complaints after Concussion (C4) questionnaire: a treatment-planning tool for military service members and veterans with mild traumatic brain injury

by myneuronews August 7, 2025

by myneuronews August 7, 2025

Background on Cognitive Complaints Cognitive complaints following a concussion, particularly in military service members and …

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Traumatic brain injury
Mental, Physical, and Social Mediators of the Relationship Between Mild Traumatic Brain Injury and Functional Impairment in U.S. Military Veterans

by myneuronews August 6, 2025

by myneuronews August 6, 2025

Mediators of Functional Impairment Functional impairment in veterans following mild traumatic brain injury (mTBI) can …

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Traumatic brain injury
Migraine-Related Burden, Treatment Interventions, and Healthcare Experiences by Race and Ethnicity: Results of the Migraine Report Card Survey

by myneuronews August 6, 2025

by myneuronews August 6, 2025

Impact of Migraine Across Racial and Ethnic Groups Migraine is a complex neurological disorder characterized …

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Traumatic brain injury
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model

by myneuronews August 6, 2025

by myneuronews August 6, 2025

Study Overview The research focuses on the development of a specialized apparatus designed to replicate …

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Functional neurological disorders
Inpatient cognitive analytic therapy for functional neurological disorder: A mixed methods four-phase single-case experimental design

by myneuronews August 6, 2025

by myneuronews August 6, 2025

Study Summary The study investigates the application of inpatient cognitive analytic therapy (CAT) tailored for …

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Functional neurological disorders
Inpatient cognitive analytic therapy for functional neurological disorder: A mixed methods four-phase single-case experimental design

by myneuronews August 6, 2025

by myneuronews August 6, 2025

Study Summary This study explored the application of inpatient cognitive analytic therapy (CAT) for individuals …

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Functional neurological disorders
Inpatient cognitive analytic therapy for functional neurological disorder: A mixed methods four-phase single-case experimental design

by myneuronews August 6, 2025

by myneuronews August 6, 2025

Cognitive Analytic Therapy Overview Cognitive Analytic Therapy (CAT) is a structured and goal-oriented form of …

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Functional neurological disorders
Inpatient cognitive analytic therapy for functional neurological disorder: A mixed methods four-phase single-case experimental design

by myneuronews August 6, 2025

by myneuronews August 6, 2025

Study Summary The study explores the use of inpatient cognitive analytic therapy (CAT) specifically tailored …

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Functional neurological disorders
Outcomes of specialist physiotherapy for functional motor disorder: the Physio4FMD RCT

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Study Summary The Physio4FMD trial represents a significant advancement in understanding how specialized physiotherapy can …

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Functional neurological disorders
Changes in brain network dynamics during functional/dissociative seizures: An exploratory pilot study on EEG microstates

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Study Summary This exploratory pilot study investigates the nuances of brain network dynamics specifically during …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]