Tag:

treatment strategies

Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Functional neurological disorders
Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Clinical Presentation and Diagnosis The clinical presentation of type 1 stiff-person syndrome (SPS) and its …

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Functional neurological disorders
Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Clinical Presentation and Diagnosis The clinical presentation of type 1 stiff-person syndrome (SPS) characterized by …

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Functional neurological disorders
Apolipoprotein E (APOE) and Alzheimer’s disease risk in a Ugandan population: A pilot case-control study

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Apolipoprotein E Genotypes and Alzheimer’s Disease The study investigated the relationship between different genotypes of …

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Dementia
Unraveling sex differences in Alzheimer’s disease and related endophenotypes with brain proteomes

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Research Context The study of Alzheimer’s disease (AD) has gained considerable momentum as researchers explore …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Electrophysiological Properties of hiPSC-Derived Neurons The study begins by examining the electrophysiological properties of human-induced …

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Functional neurological disorders
Memory processing by hippocampal adult-born neurons

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Hippocampal Function and Adult Neurogenesis The hippocampus is a critical brain region known for its …

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Functional neurological disorders
Structural signatures of language reorganization after left hemispherotomy in patients with Rasmussen’s encephalitis

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Language Reorganization Mechanisms Language reorganization following left hemispherotomy in patients with Rasmussen’s encephalitis reveals intriguing …

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Functional neurological disorders
Stroke-Like Symptoms Status-Post Tenecteplase (TNK) Administration: A Rare Case of Hemiplegic Migraine

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Clinical Presentation and Background In the context of acute neurological symptoms, the clinical presentation is …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Background and Rationale The treatment and study of Parkinson’s disease (PD) continue to evolve, particularly …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Pediatric concussion characteristics differ based on age
CONCLUSIONS: The results build on previous studies showing that younger pediatric patients sustain concussions mostly from non-sports mechanisms and endorse fewer symptoms which could be due to lower severity of injury and/or primarily relying on parent reporting of observable concussion symptoms. Pediatric concussion mechanism and presentation differ across ages, emphasizing the importance of age-appropriate symptom […]
Mild traumatic brain injury and concussion and persisting post-concussion symptoms: new guidelines to support evidence-based assessment and management in Australia and Aotearoa New Zealand
No abstract
Examining Clinic-Based Healthcare Utilization Patterns in a Specialty Concussion Care Setting
CONCLUSIONS: Initiation of concussion care within one week of injury demonstrates comparable effectiveness regardless of exact timing, although early presentation favors single-provider management while later presentation requires enhanced interdisciplinary coordination.
Evaluating Diagnostic Strategies for Pediatric Traumatic Brain Injury: A Literature-Based Clinical Decision Analysis
CONCLUSIONS: Application of CDA to pediatric TBI demonstrates the potential value of biomarker integration in improving diagnostic accuracy and optimizing CT utilization. Biomarker-augmented strategies may enhance patient safety by reducing unnecessary radiation exposure, while maintaining sensitivity for clinically important injuries. Prospective validation and real-world implementation studies are needed to confirm clinical effectiveness and cost-effectiveness.
Isolated oculomotor nerve palsy following mild traumatic brain injury: diagnostic challenges and insights from High-Resolution MRI
CONCLUSIONS: High-resolution CE-MRI proves instrumental in diagnosing isolated ONP in mild TBI patients, even without conventional radiological indicators. Early imaging and intervention may improve recovery outcomes. This study underscores the significance of including CE-MRI in evaluation protocols for ONP. It highlights the importance of further research to unravel the underlying pathophysiology and optimize therapeutic approaches […]