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treatment strategies

Functional neurological disorders
Colossal Barocaloric Effect in Liquid Crystals via Cascade Order-Disorder Transitions

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Colossal Barocaloric Effect Mechanism The colossal barocaloric effect refers to the significant change in thermal …

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Functional neurological disorders
Disordered Ru-O6 Octahedrons for Efficient and Selective Electro-oxidation of Sulfide to Sulfoxide via Boosted Surface Oxygen Kinetics

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Mechanism of Electro-oxidation Electro-oxidation processes are fundamental in transforming chemical compounds, particularly in promoting desirable …

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Functional neurological disorders
A novel cause of type 1 von Willebrand disease: impaired exocytosis of Weibel-Palade bodies due to biallelic MADD variants

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Novel Mechanism of Type 1 Von Willebrand Disease Recent research has uncovered a previously unrecognized …

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Functional neurological disorders
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Luminal Vascular Dysfunction as a Mechanism In examining how luminal vascular dysfunction contributes to blood-brain …

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Functional neurological disorders
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Luminal Glycocalyx and Its Role in Blood Brain Barrier Integrity The luminal glycocalyx is a …

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Functional neurological disorders
Transcranial magnetic stimulation as a primer for rapid improvement in functional neurological disorder: a case series

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Case Series Overview The case series presents a collaborative examination of three patients diagnosed with …

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Headaches
Aggressive Craniospinal Recurrence of a PTEN-Mutated Sinonasal Teratocarcinosarcoma: A Case Report

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Case Presentation A 45-year-old male presented with a persistently obstructed nasal passage and occasional epistaxis …

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Traumatic brain injury
Exploring the diagnostic and prognostic utility of resting state functional MRI connectivity in acute/sub-acute TBI

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Diagnostic Utility of Resting State fMRI Resting state functional magnetic resonance imaging (fMRI) has emerged …

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Functional neurological disorders
Transcranial magnetic stimulation as a primer for rapid improvement in functional neurological disorder: a case series

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Background on Functional Neurological Disorder Functional Neurological Disorder (FND) is a condition characterized by neurological …

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Traumatic brain injury
Vulnerability factors for pediatric disorders of gut-brain interaction and implications for functional impairment

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Vulnerability Factors Identification Identifying vulnerability factors for pediatric disorders of gut-brain interaction (GBI) requires a …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]