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treatment strategies

Functional neurological disorders
Singing Without Speaking: A Unique Case of Psychogenic Speech and Voice Disorder in an Adolescent

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Understanding Psychogenic Speech Disorders Psychogenic speech disorders represent a fascinating interplay between psychological well-being and …

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Functional neurological disorders
Intracranial directed connectivity links subregions of the prefrontal cortex to major depression

by myneuronews July 8, 2025

by myneuronews July 8, 2025

Study Summary The study investigated the directed connectivity between subregions of the prefrontal cortex and …

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Functional neurological disorders
Randomised feasibility study evaluating eye movement desensitisation and reprocessing therapy for functional neurological disorder (MODIFI)

by myneuronews July 8, 2025

by myneuronews July 8, 2025

Study Objectives The primary aim of this study was to evaluate the feasibility of implementing …

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Dementia
Early outpatient clinical experience with xanomeline and trospium chloride for schizophrenia: a case report

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Study Overview This article presents a detailed examination of the early outpatient clinical experiences involving …

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Headaches
Idiopathic hypertrophic pachymeningitis (IHP) causing headache in a young female

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Study Overview This study investigates idiopathic hypertrophic pachymeningitis (IHP), a rare neurological condition characterized by …

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Traumatic brain injury
New Diagnostic Criteria for Mild Traumatic Brain Injury: Medical-Legal Considerations

by myneuronews July 7, 2025

by myneuronews July 7, 2025

New Diagnostic Framework The evolution of understanding mild traumatic brain injury (mTBI) has led to …

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Traumatic brain injury
Concussion history’s impact on stability evaluation test scores in male division I lacrosse and football players

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Concussion history assessment The evaluation of concussion history is a critical component of understanding its …

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Functional neurological disorders
Functional connectome integration observed after antispastic epidural cervical spinal cord stimulation in a patient with TBI-induced disorder of consciousness: a case report

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Functional Connectome Integration Recent advances in neuroimaging have enhanced our understanding of how different brain …

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Functional neurological disorders
Retrospective Analysis of Factors Associated with a Prolonged Nucleic Acid Conversion Time in Patients with COVID-19 at Fangcang Shelter Hospital

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Background of Nucleic Acid Conversion in COVID-19 The process of nucleic acid conversion in COVID-19 …

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Traumatic brain injury
Letter to the Editor: The importance of using validated case definitions in the epidemiology of concussion

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Importance of Validated Case Definitions The use of validated case definitions in the study of …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]