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treatment strategies

Traumatic brain injury
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide …

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Functional neurological disorders
Identification and Physiological Analysis of Novel Riboflavin Transporter RFVT

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Background of Riboflavin Transporters Riboflavin, also known as vitamin B2, is an essential nutrient that …

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Functional neurological disorders
What does a migraine aura look like?-A systematic review

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Migraine Aura Characteristics Migraine aura is a fascinating phenomenon that can manifest in various ways, …

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Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Functional neurological disorders
Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Comorbid Gene Identification The identification of comorbid genes linking type 2 diabetes and migraine is …

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Traumatic brain injury
Brain health concerns in former rugby players: clinical and cognitive phenotypes

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Context of Brain Health in Rugby The discussion around brain health in former rugby players …

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Traumatic brain injury
Correlation between bispectral index values and the Glasgow Coma Scale in traumatic brain injury patients: a prospective observational study

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Study Overview This study investigates the relationship between the bispectral index (BIS) and the Glasgow …

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Traumatic brain injury
Long-Term Health-Related Quality of Life and Perceptions of Recovery in Adults Who Received Clinical Profiles Informed Care for Concussion

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Long-Term Quality of Life Outcomes Long-term health-related quality of life (HRQoL) outcomes for adults who …

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Functional neurological disorders
DYNAMIC PREDICTION WITH MULTIVARIATE LONGITUDINAL OUTCOMES AND LONGITUDINAL MAGNETIC RESONANCE IMAGING DATA

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Methodology of Longitudinal Data Analysis The methodology for longitudinal data analysis is essential for understanding …

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Functional neurological disorders
Association of Striatal Dopaminergic Depletion and Cerebral Perfusion With Cognition in Brain-First and Body-First Parkinson’s Disease

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Dopaminergic Depletion and Cognition Dopaminergic depletion in the striatum is a critical factor in understanding …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]