Tag:

treatment strategies

Functional neurological disorders
Photoactivatable Exosenolytics Activate Natural Killer Cells for Delaying Osteoarthritis

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Mechanism of Action The study explores how photoactivatable exosenolytics function by triggering specific pathways in …

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Traumatic brain injury
Impact of anticoagulant therapy on delayed intracranial haemorrhage after traumatic brain injury: A study on the role of repeat CT scans and extended observation

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Study Overview This study investigates the implications of anticoagulant therapy on the risk of delayed …

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Headaches
Combination behavioral and pharmacological interventions through telehealth platforms: Opportunities for increasing access and optimizing migraine outcomes

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Telehealth Integration for Migraine Management The integration of telehealth into migraine management represents a significant …

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Traumatic brain injury
Sex-stratified patterns in geriatric patients with mild traumatic brain injury and intracranial bleeding: a retrospective cohort study

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Background Information Mild traumatic brain injury (mTBI) presents a significant public health challenge, particularly among …

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Traumatic brain injury
In Reply: Does Mechanism of Injury Affect Recovery After Sport-Related Concussion in Basketball? A Pilot Study

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Study Overview The investigation sought to evaluate the relationship between the mechanism of injury and …

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Functional neurological disorders
Developing an Outpatient Transdisciplinary Functional Movement Disorder Program: 1-Year Experience

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Program Overview The development of an outpatient transdisciplinary functional movement disorder program was implemented to …

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Functional neurological disorders
Alterations in functional and structural connectivity in the 6-OHDA-induced Parkinsonian rat model

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Functional Connectivity Alterations In the context of Parkinson’s disease, alterations in functional connectivity have emerged …

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Traumatic brain injury
Distinct symptom recoveries based upon highest level of care in patients with sport-related concussion or traumatic brain injury and Glasgow Coma Scale 13-15

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Patient Population Characteristics The study focused on a diverse group of individuals who experienced sport-related …

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Traumatic brain injury
Factors Associated With Persisting Symptoms After Concussion in Adults With Mild TBI: A Systematic Review and Meta-Analysis

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Study Overview The investigation centered on understanding the factors that contribute to persistent symptoms following …

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Functional neurological disorders
Developing an Outpatient Transdisciplinary Functional Movement Disorder Program: 1-Year Experience

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Program Development In the evolution of a comprehensive outpatient program tailored to manage Functional Movement …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]