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  • Headaches

    Efficacy, safety, and tolerability of chenodeoxycholic acid (CDCA) in adult patients with cerebrotendinous xanthomatosis (RESTORE): a randomized withdrawal, double-blind, placebo-controlled, crossover phase 3 study

    by myneuronews April 29, 2025
    by myneuronews April 29, 2025

    Efficacy of Chenodeoxycholic Acid Chenodeoxycholic acid (CDCA) has emerged as a critical therapeutic option for …

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  • Traumatic brain injury

    Early Pupil Abnormality Frequency Predicts Poor Outcomes and Enhances International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Model Prognostication in Traumatic Brain Injury

    by myneuronews April 29, 2025
    by myneuronews April 29, 2025

    Early Pupil Abnormality and Its Significance Pupil abnormalities, such as asymmetry or non-reactivity to light, …

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  • Traumatic brain injury

    Single-Quantum Sodium MRI at 3T for the Separation of Mono- and Bi-T2 Sodium Signals

    by myneuronews April 29, 2025
    by myneuronews April 29, 2025

    Study Overview The study investigates an innovative approach to magnetic resonance imaging (MRI) aimed at …

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  • Traumatic brain injury

    Clinical Cut Point for the Pittsburgh Sleep Quality Index After Adolescent Concussion

    by myneuronews April 29, 2025
    by myneuronews April 29, 2025

    Clinical Relevance of Sleep Quality Sleep quality is a pivotal aspect of overall health and …

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  • Dementia

    FOXG1 Improves Cognitive Function in Alzheimer’s Disease by Promoting Endogenous Neurogenesis

    by myneuronews April 29, 2025
    by myneuronews April 29, 2025

    Impact of FOXG1 on Neurogenesis The role of FOXG1 in neurogenesis is increasingly being recognized …

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  • Traumatic brain injury

    Retinal manifestations of traumatic brain injury

    by myneuronews April 29, 2025
    by myneuronews April 29, 2025

    Retinal Changes Associated with Traumatic Brain Injury Traumatic brain injury (TBI) can lead to various …

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  • Traumatic brain injury

    Psychological interventions for externalising behaviours following paediatric traumatic brain injury: a systematic review and clinical practice recommendations

    by myneuronews April 28, 2025
    by myneuronews April 28, 2025

    Overview of Externalising Behaviours Externalising behaviours refer to a range of actions that move outwardly, …

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  • Traumatic brain injury

    Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

    by myneuronews April 28, 2025
    by myneuronews April 28, 2025

    Study Overview The research undertaken aimed to establish a reliable and straightforward model of mild …

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  • Headaches

    Tuberculous meningitis initially presented with low levels of pleocytosis and protein in the cerebrospinal fluid: a case report

    by myneuronews April 28, 2025
    by myneuronews April 28, 2025

    Clinical Presentation In this case report, a patient initially presented with symptoms that are often …

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  • Functional neurological disorders

    Physiotherapy for treating functional neurological disorder

    by Ioannis Mavroudis April 27, 2025
    by Ioannis Mavroudis April 27, 2025

    Functional neurological disorder (FND) presents with genuine, disabling symptoms such as weakness, tremor, and non-epileptic …

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  • Hybrid deep learning models for fake news detection: case study on Arabic and English languages
    Study Overview This research examines the effectiveness of hybrid deep learning models in identifying fake…
  • The role of surveillance MRI scans in patients with sporadic cerebral cavernous malformations
    Background on Cerebral Cavernous Malformations Cerebral cavernous malformations (CCMs) are vascular anomalies characterized by clusters…
  • Light-aversion and cephalic allodynia in an intravenous CGRP model of migraine-like behaviour in male and female rats
    Study Overview The research investigates the relationship between light aversion and cephalic allodynia, conditions often…
  • Functional Shotgun Metagenomic Insights into Gut Microbial Pathway and Enzyme Disruptions Linking Metabolism, Affect, Cognition, and Suicidal Ideation in Major Depressive Disorder
    Gut Microbial Pathways and Their Impact The human gut hosts a complex community of microorganisms…
  • Differences in symptom duration and return to sport following sport-related concussion between French-speaking Canadian and European athletes
    Symptom Duration Comparison Research into sport-related concussions has highlighted a range of experiences athletes can…

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Research

  • Extracellular Vesicle-Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review
    Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. Extracellular vesicles (EVs) have emerged as promising biomarkers for neurodegeneration, owing to their accessibility in bodily fluids and dynamic molecular cargo, including microRNAs (miRNAs). The last decade has seen accumulating evidence for miRNA dysregulation in […]
  • P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury
    The pathological basis underlying mild traumatic brain injury (mTBI)-induced long-term cognitive impairment is not fully understood. It is supposed that mTBI induces residential microglia activation rather than peripheral leukocyte infiltration to promote neuroinflammation, thus triggering myelin damage as well as cognitive impairment. The transformation of microglia towards a pro-inflammatory (M1 type) or anti-inflammatory (M2 type) […]
  • Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers
    Mild traumatic brain injury can disrupt brain function and is associated with high morbidity and healthcare utilization. While many individuals recover from mild traumatic brain injury, a significant proportion experience long-term sequelae, collectively known as post-concussion syndrome. Symptoms of post-concussion syndrome include headache, dizziness, insomnia, cognitive processing difficulties and mental health disturbances. The disease burden […]
  • Differences in symptom duration and return to sport following sport-related concussion between French-speaking Canadian and European athletes
    CONCLUSION: SRC recovery times differ significantly by geography and sex in French-speaking athletes. European athletes and males report shorter symptom and RTS durations.
  • Using Cervical Spine Proprioception and Vestibular/Oculomotor Assessments to Identify Return-to-Play Clearance Prognosis After Adolescent Concussion
    CONCLUSIONS: Cervical spine proprioception and vestibular/oculomotor symptom provocation evaluated within 3 weeks of injury were not associated with RTP clearance time, potentially reflecting the complexity and multifaceted nature of RTP decisions.

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