Tag:

treatment

Traumatic brain injury
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Overview of Neurophysiological Mechanisms Understanding the neurophysiological mechanisms underlying concussion involves delving into the complex …

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Traumatic brain injury
Traumatic brain injury graphing: A case study of Charles Whitman

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Case Background In August 1966, Charles Whitman became infamous for a tragic shooting spree in …

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Dementia
Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Link Between Olfaction and Neurodegeneration The sense of smell, or olfaction, has been increasingly recognized …

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Traumatic brain injury
Characteristics of pediatric patients with sports-related concussions: A single site retrospective review

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Patient Demographics In the examination of pediatric patients with sports-related concussions, understanding the demographics of …

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Traumatic brain injury
Quality of Life after Brain Injury in children aged six and seven years (QOLIBRI-KIDDY) – development and scale analysis of the first disease-specific self-report instrument for young children after traumatic brain injury

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Understanding Quality of Life after Brain Injury Quality of life (QoL) is a multifaceted concept …

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Headaches
Efficacy and Safety of Sodium Oxybate in Adults With Idiopathic Hypersomnia: A Randomized Controlled Trial

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Efficacy of Sodium Oxybate Sodium oxybate, a central nervous system depressant, has shown promise in …

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Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Headaches
Current Evidence in the Management of Central Skull Base Osteomyelitis: A Systematic Review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Study Overview Central Skull Base Osteomyelitis (CSBO) is a serious infection that affects the bony …

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Traumatic brain injury
Effect of Choline Alfoscerate on Cognitive Dysfunction After Mild Traumatic Brain Injury: A Single-Center Prospective Case-Control Study

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Study Overview The research aimed to investigate the effects of Choline Alfoscerate, a compound thought …

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Head injuries in intimate partner violence: cognitive, motor, and psychiatric symptoms
CONCLUSION: IPV groups reported more health issues than controls, and those with IPV-HI had the greatest rates of general health, cognitive, psychiatric, and neurobehavioral difficulties. These findings provide novel insight into IPV and IPV-related head injury outcomes.
The exercise and concussion health study (TECHS): Pilot and feasibility protocol
Mild traumatic brain injury (mTBI) is a prevalent neurological condition, affecting millions worldwide, and frequently resulting in persistent cognitive impairment that significantly impacts daily functioning. Current clinical management and recommendations lack evidence based therapeutic interventions, with treatment approaches limited to symptom monitoring and activity modification. Non-pharmaceutical interventions are needed to promote cognitive recovery and mitigate […]
Predictors of two consecutive knockout losses in ultimate fighting championship athletes
CONCLUSIONS: Among UFC athletes during this 8-year period, 23% sustained two knockout losses in a row. Predictors of two consecutive knockouts were older age, male sex, heavier weight class, and prior KO history, with prior KO history the only independent predictor. Recognizing prior knockout exposure as a key risk factor may help coaches and sports […]
Investigating associations between serum inflammatory cytokines at the time of second mild traumatic brain injury with acute neurological signs, axonal injury and behavioural outcomes in male Sprague-Dawley rats
Mild traumatic brain injury is a risk factor to sustaining future mild traumatic brain injuries and increased symptom severity and duration following a second mild traumatic brain injury. Inflammation during neurobiological recovery is hypothesized to influence susceptibility to poorer outcomes after repetitive mild traumatic brain injury. Here, we investigated whether the inflammatory response during neurobiological […]
Quantifying Mechanical Strain-Induced Membrane Damage in Early Neuronal Cells Using an In Vitro Traumatic Brain Injury Model
This protocol describes a reproducible workflow for modeling in vitro impact-induced traumatic brain injury (TBI) using a mechanical stretch system applied to differentiated SH-SY5Y human neuroblastoma cells cultured on polydimethylsiloxane (PDMS) substrates. The protocol integrates three primary components: (1) fabrication and surface modification of deformable PDMS chambers to support cellular adhesion, (2) partial differentiation of […]