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treatment

Functional neurological disorders
Alterations in functional and structural connectivity in the 6-OHDA-induced Parkinsonian rat model

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Study Summary The study investigates the effects of 6-hydroxydopamine (6-OHDA) administration in rats as a …

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Functional neurological disorders
Practicing With a Framework Mindset: A Closer Look at the Principle of Quality Improvement

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Understanding Quality Improvement Quality improvement (QI) represents a systematic approach aimed at enhancing healthcare services …

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Functional neurological disorders
Telerehabilitation for functional neurological disorders: A scoping review

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Telerehabilitation Approaches Telerehabilitation represents a transformative approach to delivering rehabilitation services, particularly for patients with …

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Functional neurological disorders
Altered Microglial Plasticity in the Periaqueductal Grey of Pre-Symptomatic Mecp2-Heterozygous Mice Following Early-Life Stress

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Microglial Plasticity Changes Microglia, the immune cells of the central nervous system, play a crucial …

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Functional neurological disorders
Diagnostic Challenges in Creutzfeldt-Jakob Disease: A Case Report of an Atypical Presentation

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Clinical Presentation of Atypical Cases The clinical presentation of atypical cases of Creutzfeldt-Jakob disease (CJD) …

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Traumatic brain injury
Neuroimaging of Mild Traumatic Injury

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Neuroimaging Techniques Neuroimaging plays a pivotal role in the assessment and understanding of mild traumatic …

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Functional neurological disorders
Telerehabilitation for functional neurological disorders: A scoping review

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Telerehabilitation Overview Telerehabilitation has emerged as a pivotal component in the management of functional neurological …

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Functional neurological disorders
Altered Microglial Plasticity in the Periaqueductal Grey of Pre-Symptomatic Mecp2-Heterozygous Mice Following Early-Life Stress

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Altered Microglial Function in Mecp2-Heterozygous Mice Recent findings reveal that microglial cells in Mecp2-heterozygous mice …

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Functional neurological disorders
Diagnostic Challenges in Creutzfeldt-Jakob Disease: A Case Report of an Atypical Presentation

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Atypical Clinical Presentation Creutzfeldt-Jakob Disease (CJD), a rare and progressively fatal neurodegenerative disorder, is primarily …

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Functional neurological disorders
Telerehabilitation for functional neurological disorders: A scoping review

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Telerehabilitation Approaches Telerehabilitation has emerged as a pivotal approach in delivering care for patients with …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]