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treatment

Functional neurological disorders
Aberrant phase separation of two PKA RIbeta neurological disorder mutants leads to mechanistically distinct signaling deficits

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Aberrant Phase Separation Mechanisms The study explores the role of aberrant phase separation in two …

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Functional neurological disorders
Seizures and Functional Deficits across Mendelian Disorders of Epigenetic Machinery: Differential Effects as a Function of Epigenetic Modifications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Understanding Mendelian Disorders Mendelian disorders are genetic conditions resulting from mutations in a single gene …

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Functional neurological disorders
The early-life gut microbiome in common pediatric diseases: roles and therapeutic implications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Early-life gut microbiome and pediatric diseases The human gut is populated by trillions of microorganisms, …

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Functional neurological disorders
Connectogram-COH: A Coherence-Based Time-Graph Representation for EEG-Based Alzheimer’s Disease Detection

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Coherence-Based Time-Graph Representation The study introduces an innovative approach for representing and analyzing EEG data …

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Functional neurological disorders
Shared Genetic Networks in Schizophrenia and Bipolar Disorder: Hippocampal Volume-Mediated Neurobiological Mechanisms

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Shared Genetic Mechanisms The investigation into the shared genetic mechanisms between schizophrenia and bipolar disorder …

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Traumatic brain injury
The Polytrauma Clinical Triad Among Women with a History of Intimate Partner Violence

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Polytrauma Clinical Triad Defined The polytrauma clinical triad is a framework that describes a specific …

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Traumatic brain injury
Feasibility trial protocol assessing the use of aerobic exercise to promote recovery from work-related concussion

by myneuronews June 12, 2025

by myneuronews June 12, 2025

Study Overview The study aimed to explore the application of aerobic exercise as a method …

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Traumatic brain injury
Characteristics of traumatic brain injury-related healthcare visits across social determinants of health: A population-based birth cohort study

by myneuronews June 12, 2025

by myneuronews June 12, 2025

Study Overview This research investigates the patterns of healthcare visits related to traumatic brain injuries …

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Traumatic brain injury
Shockwaves of War: Neurobehavioral Symptom Analysis Post-Al Asad Missile Strike, 2020

by myneuronews June 12, 2025

by myneuronews June 12, 2025

Study Overview This study investigates the neurobehavioral symptoms experienced by individuals following a missile strike …

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Traumatic brain injury
Management of sports-related concussion – a stepwise rehabilitation protocol

by myneuronews June 12, 2025

by myneuronews June 12, 2025

Concussion Assessment Techniques Assessing a sports-related concussion requires a multifaceted approach to effectively evaluate the …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]