Tag:

treatment

Headaches
Ergotamine enhances circadian amplitude and diurnally mitigates nitroglycerin-induced mechanical hypersensitivity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Effects of Ergotamine on Circadian Rhythm Recent investigations have illuminated the role of ergotamine in …

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Functional neurological disorders
Regulating aggregation of an intrinsically disordered chaperone-like casein

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Characterization of Intrinsically Disordered Chaperone-Like Casein The study of intrinsically disordered proteins (IDPs) has become …

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Functional neurological disorders
Assessment of emergency department physician perspectives on people with functional seizures

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Understanding Functional Seizures Functional seizures, also known as psychogenic non-epileptic seizures (PNES), present a complex …

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Functional neurological disorders
A conserved epilepsy-associated gene co-expression module identifies increased metabolic rate as a shared pathomechanism

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Gene Co-Expression Module Analysis The research took a deep dive into how specific genes interact …

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Functional neurological disorders
Decreased neutrophil oxidative burst activity in children with failure to thrive – a pilot study

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Background on Neutrophil Function Neutrophils are a key component of the immune system, representing the …

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Functional neurological disorders
Aggressive and Refractory Attack of AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder Treated With Ravulizumab: A Case Report

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Case Presentation We report the case of a 32-year-old woman who presented with rapid-onset severe …

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Functional neurological disorders
Convergent mapping of a tremor treatment network

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Treatment Network Overview The recent study on the treatment network for tremors offers a thorough …

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Traumatic brain injury
Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Study Overview The study aimed to investigate the effects of mild traumatic brain injury (mTBI) …

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Traumatic brain injury
Subjective cognitive functioning in adults hospitalized after traumatic brain injury: A four-year follow-up

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Cognitive Functioning Post-TBI Traumatic brain injury (TBI) can profoundly impact cognitive functioning in adults. The …

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Functional neurological disorders
Decreased neutrophil oxidative burst activity in children with failure to thrive – a pilot study

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Background and Significance The study focuses on the critical link between immune function and nutritional …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]
Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Potential Role of Serum Cytokines and Chemokines as Biomarkers of Injury Severity and Functional Outcomes Following Pediatric Traumatic Brain Injury
Traumatic brain injury (TBI) is one of the leading causes of death and neurological disability worldwide. The search for biomarkers that indicate TBI severity and prognosis with greater accuracy is ongoing. This study aimed to evaluate the significance of several neuroinflammatory cytokines and chemokines, assessing their potential as biomarkers in pediatric TBI (pTBI). This was […]
Biomarkers
CONCLUSION: These findings highlight the potential of AEV-derived inflammatory and complement proteins as biomarkers of neuroinflammation and cognitive decline in TBI-exposed aging populations. The persistence of inflammatory abnormalities in AEVs years after TBI suggests a chronic neuroinflammatory response that may underlie increased AD risk. Future work will examine interactions between inflammatory and neurodegenerative AEV biomarkers […]