Tag:

treatment

Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Landscape of Parkinson’s Disease in India Parkinson’s Disease (PD) presents a complex interplay of …

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Functional neurological disorders
Improvement of functional paralysis following unexpected comatose states

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Understanding Functional Paralysis Functional paralysis represents a complex condition often rooted in neurological and psychological …

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Functional neurological disorders
Clinical and Neuropathological Evaluations of the New Brunswick Neurological Syndrome of Unknown Cause

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Clinical Presentation and Symptoms In examining the New Brunswick Neurological Syndrome of Unknown Cause (NBNSUC), …

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Functional neurological disorders
Neuroplastic changes in patients with functional seizures following neurobehavioral therapy

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Neuroplastic Mechanisms in Functional Seizures Neuroplasticity refers to the brain’s remarkable ability to change and …

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Dementia
Relationship of the revised anticholinergic drug scale with cultured cell-based serum anticholinergic activity and cognitive measures in older adults with mild cognitive impairment or remitted depression

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Study Overview The investigation focused on understanding the relationship between a newly revised anticholinergic drug …

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Functional neurological disorders
Cholinergic degeneration in prodromal and early Parkinson’s: a link to present and future disease states

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Cholinergic Pathways in Parkinson’s Disease In the context of Parkinson’s disease, understanding the role of …

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Movement Disorders
Diagnosing migraine from genome-wide genotype data: a machine learning analysis

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Study Overview The prevalence of migraine, a debilitating neurological condition characterized by severe headaches often …

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Functional neurological disorders
Physical-functional alterations in women with chronic migraine

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Physical-functional alterations in chronic migraine Chronic migraine is a debilitating condition that can lead to …

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Headaches
Diagnosing migraine from genome-wide genotype data: a machine learning analysis

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Background on Migraine and Genomics Migraine is a prevalent and often debilitating neurological condition characterized …

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Stroke
Sleep Following a Stroke: Multimodal Evaluation of Sleep Health and Disruptions and Impact on Recovery During Acute Inpatient Rehabilitation

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Impact of Sleep on Recovery Sleep plays a crucial role in the recovery process following …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.