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  • Traumatic brain injury

    Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

    by myneuronews May 20, 2025
    by myneuronews May 20, 2025

    Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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  • Dementia

    Door Decals for Wayfinding and Redirection: A Quality Improvement Project Involving the Use of Clinical Real-Time Location Systems for Evaluation of Environmental Design Changes

    by myneuronews May 20, 2025
    by myneuronews May 20, 2025

    Project Objectives The primary goals of this quality improvement project were centered around enhancing patient …

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  • Headaches

    Long-term safety and tolerability of zavegepant 10-mg nasal spray with concomitant use of anti-calcitonin gene-related peptide monoclonal antibodies or other select preventive migraine medications: Results from a phase 2/3 open-label study

    by myneuronews May 20, 2025
    by myneuronews May 20, 2025

    Study Overview This phase 2/3 open-label study was designed to evaluate the long-term safety and …

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  • Headaches

    Raising the bar in migraine prevention: Toward freedom and optimal control

    by myneuronews May 19, 2025
    by myneuronews May 19, 2025

    Current Approaches to Migraine Prevention Migraine prevention encompasses a variety of methodologies aimed at reducing …

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  • Traumatic brain injury

    Imaging a concussion and the ensuing immune response at the blood-brain barrier

    by myneuronews May 19, 2025
    by myneuronews May 19, 2025

    Understanding the Blood-Brain Barrier The blood-brain barrier (BBB) is a highly selective permeability barrier that …

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  • Traumatic brain injury

    Optimal Diagnostic Strategies for Concussion-Related Vision Disorders: A Review

    by myneuronews May 19, 2025
    by myneuronews May 19, 2025

    Understanding Concussion-Related Vision Disorders Concussion-related vision disorders encompass a range of visual symptoms that can …

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  • Traumatic brain injury

    Predictors of skull fracture and intracerebral pathology after pediatric traumatic brain injury

    by myneuronews May 19, 2025
    by myneuronews May 19, 2025

    Predictors of Skull Fracture Pediatric traumatic brain injury (TBI) frequently involves skull fractures, which are …

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  • Traumatic brain injury

    Patient-Reported Outcomes Measurement Information System (PROMIS) outcomes: Higher odds of adverse mental health when physical function is impaired

    by myneuronews May 19, 2025
    by myneuronews May 19, 2025

    Impact of Physical Function on Mental Health Physical function is a critical component of overall …

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  • Traumatic brain injury

    The Relationship Between Sex, Fatigue, and Post-Concussion Symptoms Differs Between Those With Mild Traumatic Brain Injury Versus Trauma Control and Healthy Control Participants

    by myneuronews May 19, 2025
    by myneuronews May 19, 2025

    Study Overview In recent years, the complex interplay between sex, fatigue, and post-concussion symptoms has …

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  • Traumatic brain injury

    Somatic Symptom Disorder After Mild Traumatic Brain Injury

    by myneuronews May 19, 2025
    by myneuronews May 19, 2025

    Understanding Somatic Symptom Disorder Somatic Symptom Disorder (SSD) is characterized by the presence of physical …

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  • Hybrid deep learning models for fake news detection: case study on Arabic and English languages
    Study Overview This research examines the effectiveness of hybrid deep learning models in identifying fake…
  • The role of surveillance MRI scans in patients with sporadic cerebral cavernous malformations
    Background on Cerebral Cavernous Malformations Cerebral cavernous malformations (CCMs) are vascular anomalies characterized by clusters…
  • Light-aversion and cephalic allodynia in an intravenous CGRP model of migraine-like behaviour in male and female rats
    Study Overview The research investigates the relationship between light aversion and cephalic allodynia, conditions often…
  • Functional Shotgun Metagenomic Insights into Gut Microbial Pathway and Enzyme Disruptions Linking Metabolism, Affect, Cognition, and Suicidal Ideation in Major Depressive Disorder
    Gut Microbial Pathways and Their Impact The human gut hosts a complex community of microorganisms…
  • Differences in symptom duration and return to sport following sport-related concussion between French-speaking Canadian and European athletes
    Symptom Duration Comparison Research into sport-related concussions has highlighted a range of experiences athletes can…

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Research

  • Extracellular Vesicle-Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review
    Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. Extracellular vesicles (EVs) have emerged as promising biomarkers for neurodegeneration, owing to their accessibility in bodily fluids and dynamic molecular cargo, including microRNAs (miRNAs). The last decade has seen accumulating evidence for miRNA dysregulation in […]
  • P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury
    The pathological basis underlying mild traumatic brain injury (mTBI)-induced long-term cognitive impairment is not fully understood. It is supposed that mTBI induces residential microglia activation rather than peripheral leukocyte infiltration to promote neuroinflammation, thus triggering myelin damage as well as cognitive impairment. The transformation of microglia towards a pro-inflammatory (M1 type) or anti-inflammatory (M2 type) […]
  • Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers
    Mild traumatic brain injury can disrupt brain function and is associated with high morbidity and healthcare utilization. While many individuals recover from mild traumatic brain injury, a significant proportion experience long-term sequelae, collectively known as post-concussion syndrome. Symptoms of post-concussion syndrome include headache, dizziness, insomnia, cognitive processing difficulties and mental health disturbances. The disease burden […]
  • Differences in symptom duration and return to sport following sport-related concussion between French-speaking Canadian and European athletes
    CONCLUSION: SRC recovery times differ significantly by geography and sex in French-speaking athletes. European athletes and males report shorter symptom and RTS durations.
  • Using Cervical Spine Proprioception and Vestibular/Oculomotor Assessments to Identify Return-to-Play Clearance Prognosis After Adolescent Concussion
    CONCLUSIONS: Cervical spine proprioception and vestibular/oculomotor symptom provocation evaluated within 3 weeks of injury were not associated with RTP clearance time, potentially reflecting the complexity and multifaceted nature of RTP decisions.

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