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UCH-L1

Traumatic brain injury
Clinical Evaluation of the TBI Assay in a Representative Emergency Department Cohort

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Study Overview The evaluation centered on the efficacy and reliability of the TBI Assay within …

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Traumatic brain injury
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients

by myneuronews October 8, 2025

by myneuronews October 8, 2025

Study Overview This study examined the efficacy of three biomarkers—GFAP (Glial Fibrillary Acidic Protein), UCH-L1 …

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Traumatic brain injury
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide …

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Traumatic brain injury
Budget Impact Analysis of the Use of Specific Biomarkers GFAP and UCH-L1 in the Management of Mild Traumatic Brain Injury in Spain

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Background on Mild Traumatic Brain Injury Mild Traumatic Brain Injury (mTBI) is a significant public …

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Traumatic brain injury
The role of two brain injury biomarkers, GFAP and UCH-L1, for the management of mTBI in the Emergency Department: an observational study

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Study Overview This observational study focused on the potential role of two specific brain injury …

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Biomarkers Traumatic brain injury
Blood biomarkers in mTBI

by Ioannis Mavroudis June 22, 2024

by Ioannis Mavroudis June 22, 2024

Several studies have demonstrated that elevated levels of S100B, GFAP, UCH-L1, and NFL correlate with …

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Does Timing of Concussion in Season Affect Incidence and Recovery in Division I Collegiate Football Players? A CARE Consortium Study
CONCLUSIONS: In a multi-institution cohort of collegiate football players, preseason resulted in the highest incidence of concussions, while early and late-season concussions had significantly longer time to SR compared to preseason. These temporal patterns suggest that contextual factors may influence concussion outcomes and warrant mechanistic investigation to inform future management strategies.
Ultra-high contrast MRI of the brain and spinal cord using directly acquired and synthetic BipoLAr Inversion Recovery (BLAIR) images
Ultra-high contrast (UHC) magnetic resonance imaging (MRI) is a term used to describe magnetic resonance (MR) imaging that shows abnormalities with high contrast when little or no abnormality is seen on common conventional state-of-the-art MR images. It is achieved without the use of increased static or gradient magnetic fields. UHC can be accomplished by using […]
Functional Magnetic Resonance Imaging (fMRI) and Music Therapy for Concussion: A Case Report
Effective treatments for mild traumatic brain injury (mTBI) are limited and are insufficient to address patient symptoms and recovery. We report a case of an mTBI patient with debilitating visual symptoms who experienced profound symptom relief and increased functional capacity after music therapy (MT) (passive listening to specific music pieces). After other mTBI patients reported […]
Knowledge and Attitudes of Youth Ice Hockey Players and Their Parents Toward Concussion in the United Kingdom
Introduction and aim There is a lack of research investigating the knowledge and attitudes of youth ice hockey players and their parents toward concussion in the United Kingdom. This is a topic of increasing concern given the well-known risks associated with contact sports. Previous research in this area has primarily come from North America. The […]
Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]

UCH-L1

Clinical Evaluation of the TBI Assay in a Representative Emergency Department Cohort

Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients

Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

Budget Impact Analysis of the Use of Specific Biomarkers GFAP and UCH-L1 in the Management of Mild Traumatic Brain Injury in Spain

The role of two brain injury biomarkers, GFAP and UCH-L1, for the management of mTBI in the Emergency Department: an observational study

Blood biomarkers in mTBI