Tag:

UCH-L1

Traumatic brain injury
Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits

by myneuronews January 14, 2026

by myneuronews January 14, 2026

Study Overview This research investigates the roles of specific biomarkers—ubiquitin C-terminal hydrolase-L1 (UCH-L1), glial fibrillary …

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Traumatic brain injury
Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits

by myneuronews January 14, 2026

by myneuronews January 14, 2026

Study Overview The investigation focused on analyzing the levels of ubiquitin C-terminal hydrolase-L1 (UCH-L1), glial …

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Traumatic brain injury
Clinical Evaluation of the TBI Assay in a Representative Emergency Department Cohort

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Study Overview The evaluation centered on the efficacy and reliability of the TBI Assay within …

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Traumatic brain injury
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients

by myneuronews October 8, 2025

by myneuronews October 8, 2025

Study Overview This study examined the efficacy of three biomarkers—GFAP (Glial Fibrillary Acidic Protein), UCH-L1 …

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Traumatic brain injury
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide …

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Traumatic brain injury
Budget Impact Analysis of the Use of Specific Biomarkers GFAP and UCH-L1 in the Management of Mild Traumatic Brain Injury in Spain

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Background on Mild Traumatic Brain Injury Mild Traumatic Brain Injury (mTBI) is a significant public …

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Traumatic brain injury
The role of two brain injury biomarkers, GFAP and UCH-L1, for the management of mTBI in the Emergency Department: an observational study

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Study Overview This observational study focused on the potential role of two specific brain injury …

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Biomarkers Traumatic brain injury
Blood biomarkers in mTBI

by Ioannis Mavroudis June 22, 2024

by Ioannis Mavroudis June 22, 2024

Several studies have demonstrated that elevated levels of S100B, GFAP, UCH-L1, and NFL correlate with …

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Clinical Cut Point for the Post Concussion Symptom Inventory Following Adolescent Concussion
CONCLUSIONS: Our results suggest a PCSI cut point of 23 can distinguish between adolescents with/without a recent concussion and may provide enhanced accuracy to identify a suspected concussion in the subacute time after injury.
Sex Differences in Severity and Recovery Following Mild Traumatic Brain Injury: A Systematic Review
Background: Sex-based variations in brain structure, hormonal balance, and neurochemistry may influence symptom presentation and recovery after mild traumatic brain injury (mTBI). This systematic review investigated sex-related differences in mTBI severity, symptoms, and recovery outcomes across different injury mechanisms. Methods: This review followed PRISMA 2020 guidelines and was registered with PROSPERO (CRD420251011379). Searches were conducted […]
Driving After Concussion: The Influence of Days Since Concussion on Simulated Driving Performance Recovery
CONCLUSIONS: Clinicians should consider recommendations that support limited driving during the acute stages (24-72 hours) of concussion followed by a gradual return to driving. A longitudinal study design in a larger sample is needed to better define driving performance recovery following concussion.
Non-Pharmacological Approaches to Addressing Overweight and Obesity in Children and Adolescents with Mental Illness: A Scoping Review of Quantitative and Qualitative Evidence
Children and adolescents with mental illness are at increased risk of developing overweight and obesity, a relationship that is complex, bidirectional, and often exacerbated by the weight-related side effects of psychotropic medications. This review addressed the research question: How are overweight and obesity addressed in children and adolescents with mental illness? Following JBI and PRISMA-ScR […]
A Prefrontal Neuromodulation Route for Post-Traumatic Olfactory Dysfunction: A Perspective Supported by Recovery During Left-DLPFC rTMS
Post-traumatic olfactory dysfunction (PTOD) is a common and often persistent sequela of mild traumatic brain injury (mTBI), with limited evidence-based treatment options. We propose that high-frequency rTMS applied to the left dorsolateral prefrontal cortex (DLPFC) may support olfactory recovery via top-down modulation of distributed olfactory, attentional, and reward networks, and we outline key mechanistic and […]