Tag:

variability

Functional neurological disorders
Low intensity rTMS in adolescent mice affects visuomotor behaviour with no impact on visual topography

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Effects of Low Intensity rTMS on Visuomotor Behaviour The study examined the effects of low-intensity …

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Traumatic brain injury
Use of physical exertion to enhance objective testing following mild traumatic brain injury: a systematic review

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Physical Exertion as a Rehabilitation Strategy Physical exertion has gained recognition as a potential rehabilitative …

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Traumatic brain injury
Clinical comparisons between post-traumatic headache and migraine: A cross-sectional study

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Study Overview This study examined the clinical characteristics of post-traumatic headaches (PTH) in comparison to …

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Headaches
Efficacy, safety, and tolerability of chenodeoxycholic acid (CDCA) in adult patients with cerebrotendinous xanthomatosis (RESTORE): a randomized withdrawal, double-blind, placebo-controlled, crossover phase 3 study

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Efficacy of Chenodeoxycholic Acid Chenodeoxycholic acid (CDCA) has emerged as a critical therapeutic option for …

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Functional neurological disorders
Electroencephalographic aspects and phenotypic characteristics in children with autism

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Electroencephalographic Findings in Autism Electroencephalography (EEG) has become an essential tool in understanding the neurological …

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Dementia
Resistance and resilience to Alzheimer’s disease in Down syndrome

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Understanding Alzheimer’s Disease in Down Syndrome Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition characterized …

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Movement Disorders
Paired Deep Brain Stimuli Elicit Short-Term Facilitation in Globus Pallidus Interna and Subthalamic Nucleus

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Study Overview In recent years, the understanding of how deep brain stimulation (DBS) influences neural …

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Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomics Techniques in Glycine Receptor Analysis Understanding the complex interactions within neuronal proteins is critical …

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Traumatic brain injury
The role of cardiovascular response as a predictor of neurologic disability in children with brain injury – a pilot study

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Background and Rationale The interaction between the cardiovascular system and the brain is complex and …

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Traumatic brain injury
Concussions Are Associated With Increases in Blood Pressure and Cardiovascular Risk in American-Style Football Athletes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Impact of Concussions on Cardiovascular Health Recent research has highlighted a concerning link between concussions …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.