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Monthly Archives

February 2024

  • Traumatic brain injury

    Understanding the Risks: Stroke Incidence after Mild Traumatic Brain Injury

    by Ioannis Mavroudis February 28, 2024
    by Ioannis Mavroudis February 28, 2024

    Mild traumatic brain injury (mTBI), commonly referred to as concussion, has been increasingly recognized for …

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  • Medical professionalsPost traumatic epilepsyTraumatic brain injury

    Understanding the Pathophysiology of Post-Traumatic Epilepsy

    by Ioannis Mavroudis February 14, 2024
    by Ioannis Mavroudis February 14, 2024

    Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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  • Neurology Pioneers

    A Tribute to a Luminary: Farewell to Professor Stavros J. Baloyannis

    by Ioannis Mavroudis February 13, 2024
    by Ioannis Mavroudis February 13, 2024

    In bidding farewell to Professor Stavros J. Baloyannis, we celebrate a luminary whose contributions to …

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  • Medical professionalsTraumatic brain injury

    Overview of Classification Systems and Diagnostic Criteria for Traumatic Brain Injury Syndromes

    by Ioannis Mavroudis February 13, 2024
    by Ioannis Mavroudis February 13, 2024

    This article presents a comprehensive overview of the classification systems for traumatic brain injuries (TBI) …

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  • Medical professionalsPost traumatic epilepsyTraumatic brain injury

    Epidemiology of Post-Traumatic Epilepsy after Mild Traumatic Brain Injury

    by Ioannis Mavroudis February 13, 2024
    by Ioannis Mavroudis February 13, 2024

    In exploring the epidemiological facets of mild traumatic brain injury (mTBI) and its subsequent risk …

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  • NeuroVideos

    Unraveling the Mystery Personality Traits in PostConcussion syndrome

    by Ioannis Mavroudis February 13, 2024
    by Ioannis Mavroudis February 13, 2024

    Join Dr. Mavroudis, a consultant neurologist, as we explore the fascinating changes in personality traits …

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  • NeuroVideosTraumatic brain injury

    Concussion Chronicles

    by Ioannis Mavroudis February 12, 2024
    by Ioannis Mavroudis February 12, 2024

    Get the facts on concussions in under 60 seconds! Dr. Mavroudis, a consultant neurologist, breaks …

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  • Medical professionalsPost traumatic headache

    Post-traumatic headache: Treatment Overview

    by Ioannis Mavroudis February 12, 2024
    by Ioannis Mavroudis February 12, 2024

    In the management of post-traumatic headaches (PTH), a multifaceted approach is essential due to the …

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  • Medical professionals

    Incidence of Post-Traumatic Headaches After Mild Traumatic Brain Injury

    by Ioannis Mavroudis February 12, 2024
    by Ioannis Mavroudis February 12, 2024

    The prevalence of post-traumatic headache (PTH) following mild traumatic brain injury (mTBI) exhibits significant variability, …

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  • Medical professionalsTraumatic brain injury

    The Mayo classification system

    by Ioannis Mavroudis February 12, 2024
    by Ioannis Mavroudis February 12, 2024

    The Mayo Classification System for Traumatic Brain Injuries (TBIs) offers a nuanced approach to diagnosing …

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  • Estimated Glucose Disposal Rate and Risk of Stroke and Dementia in Nondiabetics: A UK Biobank Prospective Cohort Study
    Study Overview The investigation centered around the relationship between glucose disposal rate and the risk…
  • Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip
    Study Overview This research focuses on the cellular mechanisms involved in concussive injuries, specifically examining…
  • Spontaneous Resolution of Pharyngeal Myoclonus in a Child: An Uncommon Case With Objective Clicking Sounds
    Case Presentation A case was identified involving a child who presented with an unusual condition…
  • Burden of Intracranial Hypertension and Patterns of Brain Injury on MRI: Secondary Analysis of the 2014-2017 “Approaches and Decisions for Acute Pediatric TBI” Study
    Burden of Intracranial Hypertension Intracranial hypertension, characterized by elevated pressure within the skull, presents a…
  • Player-Level Tackle Training Interventions in Tackle-Collision Sports: A Systematic Scoping Review
    Study Overview The investigation into player-level tackle training interventions within collision sports, notably rugby and…

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Research

  • Non-invasive vagus nerve stimulation is associated with the reduction in persistent post-concussion symptoms: an observational study
    INTRODUCTION: Traumatic brain injury (TBI) remains a major public health challenge, with mild TBI (mTBI) frequently resulting in persistent cognitive, affective, and somatic symptoms. Non-invasive vagus nerve stimulation (nVNS) has demonstrated potential in reducing neuroinflammation and promoting recovery in preclinical TBI models. This retrospective, observational study assessed the impact of adjunctive nVNS on postconcussive symptoms […]
  • Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region
    CONCLUSIONS: Spautin-1 alleviates depression-like behaviors in mice following mild TBI by inhibiting the MMP3 signaling pathway in microglia within the CA1 region of the hippocampus, indicating a potential therapeutic strategy for addressing post-TBI depression.
  • Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip
    Traumatic brain injuries (TBIs) are a risk factor for Alzheimer's disease (AD), and share several important pathological features including the development of neurofibrillary tangles (NFT) of tau protein. While this association is well established, the underlying pathogenesis is poorly defined and current treatment options remain limited, necessitating novel methods and approaches. In response we developed […]
  • Detecting mild traumatic brain injury with MEG scan data: One-vs-K-sample tests
    Magnetoencephalography (MEG) scanner has been shown to be more accurate than other medical devices in detecting mild traumatic brain injury (mTBI). However, MEG scan data in certain spectrum ranges can be skewed, multimodal, and heterogeneous which can mislead the conventional case-control analysis that requires the data to be homogeneous and normally distributed within the control […]
  • Risk of Mortality Among Adult Females Diagnosed with Traumatic Brain Injury in an Academic Medical System
    The objective of this retrospective cohort study was to evaluate mortality risk over five years among 6,432 female patients with a health care encounter diagnosis of TBI from hospitals and outpatient clinics within a university health system. We used TBI severity, defined by the Centers for Disease Control and Department of Defense/Veterans Affairs: mild, moderate/severe/penetrating, […]

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