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"Insights into mTBI, PCS, and FND — One Synapse at a Time" A bit more creative, nodding to neuroscience roots while covering your full range.
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Ioannis Mavroudis

Ioannis Mavroudis

  • Brain & Crime

    Phillip Adams and the Tragic Impact of CTE: Understanding the Role of Brain Injury in Violent Behavior

    by Ioannis Mavroudis September 15, 2024
    by Ioannis Mavroudis September 15, 2024

    The case of Phillip Adams, a former NFL player who committed a mass murder in …

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  • Brain & Crime

    The Moors Murders: A Chilling Crime and the Neurobiological Profile of Its Perpetrators

    by Ioannis Mavroudis September 14, 2024
    by Ioannis Mavroudis September 14, 2024

    The Moors Murders: A Dark Chapter in British History The Moors Murders remain one of …

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  • Brain & Crime

    Neurobiological Insights into the Mind of a Cold-Blooded Criminal: A Detailed Brain Analysis

    by Ioannis Mavroudis September 14, 2024
    by Ioannis Mavroudis September 14, 2024

    One of the most horrific crimes in the history of Greece. For the way it …

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  • Traumatic brain injury

    Is Post-Concussion Syndrome a Functional Disorder?

    by Ioannis Mavroudis September 14, 2024
    by Ioannis Mavroudis September 14, 2024

    Post-Concussion Syndrome (PCS) is a complex and often misunderstood condition that can arise after a …

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  • Traumatic brain injury

    The Role of Neuroimaging and Machine Learning in Understanding Mild Traumatic Brain Injury (mTBI)

    by Ioannis Mavroudis September 13, 2024
    by Ioannis Mavroudis September 13, 2024

    Mild traumatic brain injury (mTBI), commonly referred to as a concussion, is one of the …

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  • Traumatic brain injury

    Understanding Markov Blankets and Their Role in Brain Function and Injury

    by Ioannis Mavroudis September 13, 2024
    by Ioannis Mavroudis September 13, 2024

    The brain is an incredibly complex system, constantly interacting with both internal processes and external …

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  • Traumatic brain injury

    Caffeine and Concussion Recovery: Benefits, Drawbacks, and Recommendations

    by Ioannis Mavroudis September 9, 2024
    by Ioannis Mavroudis September 9, 2024

    Caffeine appears to have a complex relationship with concussion recovery and post-concussion syndrome (PCS). Based …

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  • Traumatic brain injury

    Understanding “Internal Fake News”: The Link Between Concussion, Sensory Alterations, and Emotional Health

    by Ioannis Mavroudis June 29, 2024
    by Ioannis Mavroudis June 29, 2024

    Concussions and post-concussion symptoms significantly impact the brain’s ability to process and integrate sensory information, …

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  • Traumatic brain injury

    Differentiating Between Concussion, Psychological Symptoms, and Malingering Using the ImPACT Test

    by Ioannis Mavroudis June 25, 2024
    by Ioannis Mavroudis June 25, 2024

    The Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is a vital tool in the assessment …

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  • BiomarkersTraumatic brain injury

    Blood biomarkers in mTBI

    by Ioannis Mavroudis June 22, 2024
    by Ioannis Mavroudis June 22, 2024

    Several studies have demonstrated that elevated levels of S100B, GFAP, UCH-L1, and NFL correlate with …

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  • Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
    Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
  • Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
    Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
  • Update on functional vestibular and gait disorders
    Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
  • Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
    Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
  • Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
    Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

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Research

  • Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
    Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
  • Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
    Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
  • Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
    CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]
  • Management of the paediatric patient with acute head trauma
    Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
  • Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
    CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.

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