Dementia: Clinical Challenges
Dementia Overview Dementia is a collective term that describes a range of cognitive impairments severe enough to interfere with daily […]
Dementia: Clinical Challenges Read Post »
Development and validation of a two-step shared parameter model for dementia imputation in the Cardiovascular Health Study Cohort
Study Overview The research focused on addressing the challenges associated with missing data in dementia assessments within the Cardiovascular Health
Molecular Complexities of Dementia: PAISA Mutations and Targeting TAF2N as Therapeutic Avenues
Molecular Mechanisms of PAISA Mutations PAISA mutations, identified as contributing factors to dementia, particularly affect various molecular pathways critical for
Free Water Elevation in Alzheimer’s Disease: Influence of Amyloid-Beta Deposition Beyond Brain Cell Loss
Background on Amyloid-Beta and Alzheimer’s Disease Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline, memory
Sleep and circadian health in the UK Biobank: Report on the 2023 sleep questionnaire enhancement
Study Overview The UK Biobank has undertaken a significant enhancement to its dataset with the introduction of a 2023 sleep
Prevalence and clinical effects of Lewy Body pathology in non-prion rapidly progressive dementias: a retrospective cohort study
Study Overview The research investigates the occurrence and impact of Lewy Body pathology among individuals suffering from rapidly progressive dementias
Barriers and facilitators to implementing strategies for reducing inappropriate antipsychotic use in long-term care: a scoping review
Background on Antipsychotic Use in Long-Term Care Antipsychotic medications are frequently prescribed in long-term care facilities, particularly for individuals with
SSEA3 and CD105 positivity are associated with the treatment potency of human neural crest-derived nasal turbinate stem cells for Alzheimer’s disease
Study Overview This study investigates the potential therapeutic effects of stem cells derived from human neural crest in the treatment
Epidemiological trends and cross-country inequalities in the global burden of Alzheimer’s disease and other dementias in postmenopausal women from 1990 to 2021
Epidemiological trends Recent data illustrate a concerning rise in the prevalence and incidence of Alzheimer’s disease and other dementias, particularly
Unravelling genetic susceptibility and causal factors in liver health using MRI quantification of inflammation, fat and iron in the liver
Study Overview The research focused on exploring the complex interplay between genetic predispositions and environmental influences that affect liver health,