Category:

Dementia

Dementia
Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Cognitive Impairment Detection Cognitive impairment represents a spectrum of conditions that affect an individual’s cognitive …

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Dementia
Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Study Overview The study investigated the changes in specific biomarkers in the blood of patients …

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Dementia
Regional cortical network atrophy predicts progression to dementia in the Lewy body diseases

by myneuronews December 7, 2025

by myneuronews December 7, 2025

Cortical Network Atrophy and Dementia The condition known as dementia can manifest through various neurodegenerative …

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Dementia
Differential microglial responses to structurally distinct alpha-synuclein polymorphs

by myneuronews December 6, 2025

by myneuronews December 6, 2025

Differential Responses of Microglia Microglia, the resident immune cells of the central nervous system, exhibit …

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Dementia
Regional disparities of antidementia drug treatment in Germany: what can we learn for the new generation of Alzheimer’s therapies

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Antidementia Drug Treatment Patterns Antidementia medications are primarily designed to manage symptoms associated with cognitive …

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Dementia
Assessing the health-related quality of life in informal caregivers of Alzheimer’s Disease: evidence from Malaysia

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Health-Related Quality of Life in Caregivers The health-related quality of life (HRQoL) among informal caregivers …

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Dementia
Neuroprotective effects of hyperbaric oxygen therapy on vascular cognitive impairment in hypoperfused mice via miR-137-3p/TRAF3 pathway

by myneuronews November 29, 2025

by myneuronews November 29, 2025

Study Overview The research focuses on the protective effects of hyperbaric oxygen therapy (HBOT) against …

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Dementia
Identification of expanded and interrupted ATXN2 repeat expansions in Parkinson’s disease and Lewy Body Dementia cohorts

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Study Overview This research investigates the presence and significance of expanded and interrupted repeat expansions …

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Dementia
Geriatric core competencies for non-geriatricians and nurses: a scoping review

by myneuronews November 26, 2025

by myneuronews November 26, 2025

Study Overview This scoping review aims to identify and categorize the core competencies necessary for …

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Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

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Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI): A Scoping Review
CONCLUSION: Vestibular dysfunction is prevalent among individuals with moderate-to-severe TBI, although the methods of assessment vary. Future studies should aim to be more consistent in documenting the severity of TBI, the evaluation of vestibular dysfunction, and determining interventions that are most beneficial for this population.
Association of sports and physical activity with mild traumatic brain injury and behavioral and neurocognitive function
CONCLUSION: Participation in soccer and/or climbing showed positive associations with mTBI, while participation in yoga showed a negative association. Sports/PA participation was related to better behavioral/emotional and neurocognitive functioning, regardless of children's injury history.
Educational Perspectives on Compassionate Concussion Care: A Scoping Review
CONCLUSION: This review highlights the implicit paradigms shaping concussion-care education and their limitations for cultivating compassion. Constructivism offers the most promise for advancing compassionate practice by fostering collaboration, reflection, and learner agency. Given the interpersonal, cognitive and contextual demands of concussion care, adopting a constructivist orientation may better prepare physicians to meet patient and caregiver […]
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared with Orthopedic Injury
Pediatric traumatic brain injury (TBI) triggers biological changes that may differ from those observed in non-brain injuries. Brain-derived neurotrophic factor (BDNF) DNA methylation (DNAm) may serve as a novel, dynamic biomarker of the brain's response and help identify TBI-specific epigenetic patterns relevant to later recovery. Therefore, the purpose of this study was to examine whether […]
Patterns, severity, and outcomes of traumatic brain injury in a regional referral hospital in Kenya: a retrospective cohort study
CONCLUSION: The study highlights the high burden of preventable TBI from RTAs and assaults in this setting. The high assault rate, low imaging access, and limited neurosurgical intervention capacity are major concerns. While the findings are limited to admitted patients and short-term outcomes, they underscore the urgent need for targeted road safety initiatives, improved access […]