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Headaches

Headaches
The P2Y13 receptor-mediated microglial morphological transformation through the p38MAPK signaling pathway contributes to central sensitization in a murine model of chronic migraine

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview The primary objective of this research was to investigate the role of the …

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Headaches
Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis

by myneuronews December 13, 2025

by myneuronews December 13, 2025

Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in …

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Headaches
Vestibular migraine vs. migraine only: integrated transcriptome-clinical profiling reveals shared inflammation and divergent metabolic pathways for targeted therapy

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This research investigates the similarities and differences between vestibular migraine and typical migraine …

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Headaches
The use of triptans and other acute treatments for the management of migraine in routine clinical practice in England: a retrospective cohort study using the Clinical Practice Research Datalink (CPRD)

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Study Overview This research investigated the utilization of triptans and other immediate treatment options for …

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Headaches
Harnessing the power of plant gums: A detailed review of their bioactive compounds and therapeutic benefits

by myneuronews December 7, 2025

by myneuronews December 7, 2025

Bioactive Compounds in Plant Gums Plant gums are complex polysaccharides produced by various plant species, …

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Headaches
Co-production and validation of an online resource to support the diagnosis of migraine

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Resource Development The development of the online resource aimed at aiding the diagnosis of migraine …

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Headaches
Interoception in migraine is characterised by normal accuracy but altered sensibility and behaviour

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Interoception and Migraine Interoception refers to the ability to perceive internal bodily states, which plays …

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Headaches
Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of …

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Headaches
Symptoms of allodynia and pain thresholds amongst those with acute post-traumatic headache attributed to mild traumatic brain injury: a prospective, longitudinal study

by myneuronews November 29, 2025

by myneuronews November 29, 2025

Study Overview This research investigates the presence of allodynia, a condition where normally non-painful stimuli …

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Headaches
An update on hypophysitis

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Study Overview Recent research has focused on the complexities of hypophysitis, an inflammation of the …

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Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium
CONCLUSIONS: These findings collectively identify COL4A1 deficiency as a sensitizing factor for post-traumatic visual dysfunction and demonstrate that ASC-CCM exerts therapeutic effects by preserving retinal vascular structure and modulating inflammatory responses, positioning it as a promising candidate for treating TBI-related ocular neurovascular injury.
Hollow CuS nanocubes enhance serum metabolic profiles for rapid diagnosis and severity grading of traumatic brain injury
Traumatic brain injury (TBI) remains a significant global health burden and demands rapid, objective diagnostics that work outside imaging suites and intensive lab workflows. Here, we developed a copper sulfide (CuS) nanocube-assisted laser desorption/ionization mass spectrometry (LDI-MS) platform to acquire serum metabolic profiles (SMPs) with high sensitivity, low background in the low-m/z region, and excellent […]
Attention-Deficit/Hyperactivity Disorder Following Mild Traumatic Brain Injury in Children: A Retrospective Exploratory Study
Introduction This study examines whether attention-deficit/hyperactivity disorder (ADHD) can develop after traumatic brain injury in children. Overlapping acute symptoms can hinder early identification and diagnosis. We investigated whether demographic or acute clinical features are associated with the development of secondary ADHD (S-ADHD) following mild pediatric traumatic brain injury. Materials and methods We conducted a retrospective […]
Ultra-high contrast MRI: a new technique for recognizing secondary changes to the brain in patients with persistent symptoms following traumatic brain injury
CONCLUSION: The whiteout sign was strongly associated with being in the symptomatic group and is a potential biomarker for recognition of secondary changes to the brain in patients with persistent symptoms following TBI.
Transcranial direct current stimulation (tDCS) in conscious mice: a refined method for repetitive applications without restraint
Transcranial direct current stimulation (tDCS) for painless, non-invasive brain stimulation is a promising approach to enhance recovery after stroke. However, the precise molecular and cellular mechanisms underlying the effects of tDCS remain unclear, impeding its use in humans and necessitating research in experimental animals. Unlike humans, who receive tDCS fully awake, experimental models of tDCS […]