Category:

Headaches

Headaches
Site-specific pain dynamics: associations between accelerometer-measured physical activity patterns and pain in older adults

by myneuronews December 17, 2025

by myneuronews December 17, 2025

Study Overview The investigation focused on understanding the intricate relationship between physical activity levels, as …

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Headaches
The P2Y13 receptor-mediated microglial morphological transformation through the p38MAPK signaling pathway contributes to central sensitization in a murine model of chronic migraine

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview The primary objective of this research was to investigate the role of the …

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Headaches
Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis

by myneuronews December 13, 2025

by myneuronews December 13, 2025

Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in …

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Headaches
Vestibular migraine vs. migraine only: integrated transcriptome-clinical profiling reveals shared inflammation and divergent metabolic pathways for targeted therapy

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This research investigates the similarities and differences between vestibular migraine and typical migraine …

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Headaches
The use of triptans and other acute treatments for the management of migraine in routine clinical practice in England: a retrospective cohort study using the Clinical Practice Research Datalink (CPRD)

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Study Overview This research investigated the utilization of triptans and other immediate treatment options for …

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Headaches
Harnessing the power of plant gums: A detailed review of their bioactive compounds and therapeutic benefits

by myneuronews December 7, 2025

by myneuronews December 7, 2025

Bioactive Compounds in Plant Gums Plant gums are complex polysaccharides produced by various plant species, …

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Headaches
Co-production and validation of an online resource to support the diagnosis of migraine

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Resource Development The development of the online resource aimed at aiding the diagnosis of migraine …

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Headaches
Interoception in migraine is characterised by normal accuracy but altered sensibility and behaviour

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Interoception and Migraine Interoception refers to the ability to perceive internal bodily states, which plays …

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Headaches
Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of …

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Headaches
Symptoms of allodynia and pain thresholds amongst those with acute post-traumatic headache attributed to mild traumatic brain injury: a prospective, longitudinal study

by myneuronews November 29, 2025

by myneuronews November 29, 2025

Study Overview This research investigates the presence of allodynia, a condition where normally non-painful stimuli …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]
Potential Role of Serum Cytokines and Chemokines as Biomarkers of Injury Severity and Functional Outcomes Following Pediatric Traumatic Brain Injury
Traumatic brain injury (TBI) is one of the leading causes of death and neurological disability worldwide. The search for biomarkers that indicate TBI severity and prognosis with greater accuracy is ongoing. This study aimed to evaluate the significance of several neuroinflammatory cytokines and chemokines, assessing their potential as biomarkers in pediatric TBI (pTBI). This was […]
Biomarkers
CONCLUSION: These findings highlight the potential of AEV-derived inflammatory and complement proteins as biomarkers of neuroinflammation and cognitive decline in TBI-exposed aging populations. The persistence of inflammatory abnormalities in AEVs years after TBI suggests a chronic neuroinflammatory response that may underlie increased AD risk. Future work will examine interactions between inflammatory and neurodegenerative AEV biomarkers […]