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Headaches

Headaches
The P2Y13 receptor-mediated microglial morphological transformation through the p38MAPK signaling pathway contributes to central sensitization in a murine model of chronic migraine

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview The primary objective of this research was to investigate the role of the …

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Headaches
Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis

by myneuronews December 13, 2025

by myneuronews December 13, 2025

Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in …

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Headaches
Vestibular migraine vs. migraine only: integrated transcriptome-clinical profiling reveals shared inflammation and divergent metabolic pathways for targeted therapy

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This research investigates the similarities and differences between vestibular migraine and typical migraine …

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Headaches
The use of triptans and other acute treatments for the management of migraine in routine clinical practice in England: a retrospective cohort study using the Clinical Practice Research Datalink (CPRD)

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Study Overview This research investigated the utilization of triptans and other immediate treatment options for …

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Headaches
Harnessing the power of plant gums: A detailed review of their bioactive compounds and therapeutic benefits

by myneuronews December 7, 2025

by myneuronews December 7, 2025

Bioactive Compounds in Plant Gums Plant gums are complex polysaccharides produced by various plant species, …

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Headaches
Co-production and validation of an online resource to support the diagnosis of migraine

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Resource Development The development of the online resource aimed at aiding the diagnosis of migraine …

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Headaches
Interoception in migraine is characterised by normal accuracy but altered sensibility and behaviour

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Interoception and Migraine Interoception refers to the ability to perceive internal bodily states, which plays …

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Headaches
Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of …

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Headaches
Symptoms of allodynia and pain thresholds amongst those with acute post-traumatic headache attributed to mild traumatic brain injury: a prospective, longitudinal study

by myneuronews November 29, 2025

by myneuronews November 29, 2025

Study Overview This research investigates the presence of allodynia, a condition where normally non-painful stimuli …

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Headaches
An update on hypophysitis

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Study Overview Recent research has focused on the complexities of hypophysitis, an inflammation of the …

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Clinical Cut Point for the Post Concussion Symptom Inventory Following Adolescent Concussion
CONCLUSIONS: Our results suggest a PCSI cut point of 23 can distinguish between adolescents with/without a recent concussion and may provide enhanced accuracy to identify a suspected concussion in the subacute time after injury.
Sex Differences in Severity and Recovery Following Mild Traumatic Brain Injury: A Systematic Review
Background: Sex-based variations in brain structure, hormonal balance, and neurochemistry may influence symptom presentation and recovery after mild traumatic brain injury (mTBI). This systematic review investigated sex-related differences in mTBI severity, symptoms, and recovery outcomes across different injury mechanisms. Methods: This review followed PRISMA 2020 guidelines and was registered with PROSPERO (CRD420251011379). Searches were conducted […]
Driving After Concussion: The Influence of Days Since Concussion on Simulated Driving Performance Recovery
CONCLUSIONS: Clinicians should consider recommendations that support limited driving during the acute stages (24-72 hours) of concussion followed by a gradual return to driving. A longitudinal study design in a larger sample is needed to better define driving performance recovery following concussion.
Non-Pharmacological Approaches to Addressing Overweight and Obesity in Children and Adolescents with Mental Illness: A Scoping Review of Quantitative and Qualitative Evidence
Children and adolescents with mental illness are at increased risk of developing overweight and obesity, a relationship that is complex, bidirectional, and often exacerbated by the weight-related side effects of psychotropic medications. This review addressed the research question: How are overweight and obesity addressed in children and adolescents with mental illness? Following JBI and PRISMA-ScR […]
A Prefrontal Neuromodulation Route for Post-Traumatic Olfactory Dysfunction: A Perspective Supported by Recovery During Left-DLPFC rTMS
Post-traumatic olfactory dysfunction (PTOD) is a common and often persistent sequela of mild traumatic brain injury (mTBI), with limited evidence-based treatment options. We propose that high-frequency rTMS applied to the left dorsolateral prefrontal cortex (DLPFC) may support olfactory recovery via top-down modulation of distributed olfactory, attentional, and reward networks, and we outline key mechanistic and […]