Stroke

Jiri Vanicek, Petra Cimflova, Martin Bulik, Jiri Jarkovsky, Veronika Prelecova, Viktor Szeder, Ondrej Volny January 14, 2019

Background: In randomized clinical trials, mechanical thrombectomy (MT) was proved to be a highly effective treatment of acute ischemic stroke which improved clinical outcomes. Some of the trials used automated computed tomography perfusion (CTP) analysis for selection of participants. We present a single-center experience with CTP selection and comparison with CTP trials.… Read More...

Daniel Vela-Duarte, Eric Nyberg, Stefan Sillau, Amy Pate, Paula Castellanos, Daniel B. Chastain, Carlos Franco-Paredes, Andrés F. Henao-Martínez January 14, 2019

Cryptococcal meningitis carries a high mortality, and survivors are left with considerable neurologic sequelae and marked disability. We lack a clear understanding of the pathogenesis of neurologic sequelae and description of stroke features in this population. We aim to describe clinical and radiographic features and predictors of stroke in a cohort of patients with cryptococcal meningitis.… Read More...

Ai Ogawa Ito, Akihiro Shindo, Yuichiro Ii, Hidehiro Ishikawa, Akira Taniguchi, Masato Shiba, Naoki Toma, Hidenori Suzuki, Hidekazu Tomimoto January 14, 2019

Cerebral microbleeds (MBs) have been often observed due to the development of imaging devices, and are classified to deep and lobar MBs. Lobar MBs are strongly associated with cerebral amyloid angiopathy. Here, we report 3 cases of lobar MBs that developed after small cortical ischemic stroke.… Read More...

Junjiang Liu, Han Xiao, Zhiping Hu January 14, 2019

Percheron infarction, arising from occlusion of the Artery of Percheron, is few, which can result in bilateral thalamic and mesencephalic infarctions. We herein showcase a confirmed case of the Percheron infarction at the admission day, in which the patient advanced into severe multiple posterior circulation infarcts, along with petechial hemorrhage within the infarcts, even given the right therapy without delay.… Read More...

Chika Kitabayashi, Yasuo Ito, Hitoshi Kawasaki, Ai Tanaka, Ryoji Nishioka, Masamizu Yamazato, Keisuke Ishizawa, Toshinori Nagai, Makiko Hirayama, Kazushi Takahashi, Toshimasa Yamamoto, Nobuo Araki January 14, 2019

Background: The purpose of this study was to investigate the effects of yokukansan on forebrain ischemia. Because we can measure nitric oxide production and hydroxyl radical metabolism continuously, we investigated the effect of yokukansan on nitric oxide production and hydroxyl radical metabolism in cerebral ischemia and reperfusion.… Read More...

Kosuke Matsuzono, Lisa Nagaoka, Masayuki Suzuki, Younhee Kim, Tadashi Ozawa, Takafumi Mashiko, Haruo Shimazaki, Reiji Koide, Shigeru Fujimoto January 14, 2019

Fatalities following intravenous recombinant tissue-type plasminogen activator therapy have been reported. Major fatal complications following intravenous recombinant tissue-type plasminogen activator therapy include intracranial hemorrhage, aortic dissection, and extracranial bleeding. However, the possibility that intravenous recombinant tissue-type plasminogen activator therapy itself paradoxically induces synchronized multiple cerebral novel infarctions has never been considered.… Read More...

Nan N. Jiang, Crystal Fong, Demetrios J. Sahlas, Sandra Monteiro, Ramiro Larrazabal January 14, 2019

Purpose: Recent trials have demonstrated superior outcomes with combination IV-tPA and endovascular therapy (EVT) within 6 hours of symptom onset in patients with proximal vessel occlusion (ICA, M1, or proximal M1/M2) compared to IV-tPA alone. The current standard of diagnosis for consideration of EVT is CT angiogram (CTA).… Read More...

Xiaofan Guo, Zhao Li, Ying Zhou, Shasha Yu, Hongmei Yang, Liqiang Zheng, Yamin Liu, Yingxian Sun January 12, 2019

Stroke burden is extremely high in Chinese hypertensive population. Novel biomarkers for cardiovascular diseases can be detected by metabolomic profiling of human fluids. We aim to find a panel of distinctive plasma metabolites for predicting incident ischemic stroke in hypertensive patients.… Read More...

Rita Marinheiro, Leonor Parreira, Pedro Amador, Cláudia Lopes, Andreia Fernandes, Dinis Mesquita, José Farinha, Marta Fonseca, Tatiana Duarte, Rui Caria January 12, 2019

Background: Atrial high-rate episodes (AHREs) are common in pacemaker patients. Our aims were to compare patients with AHREs to those without them and to assess if, in those with AHREs, the initiation of oral anticoagulation (OAC) has any clinical impact on the occurrence of ischemic and hemorrhagic events.… Read More...

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