Stroke

Yen-Ju Lung, Wei-Chieh Weng, Chia-Lun Wu, Wen-Yi Huang January 12, 2019

Background: Aggressive lipid-lowering treatment reduces the risk of cardiovascular events, but remains controversial in stroke patients. We investigate the influence of total cholesterol level on 5-year outcomes of ischemic stroke patients with high-grade internal carotid artery (ICA) stenosis and poststroke functional dependence.Methods: One-hundred and ninety-six acute ischemic stroke patients with high-grade ICA stenosis and modified Rankin Scale score ≥ 3 upon discharge were enrolled and prospectively observed for 5 years.… Read More...

Masashi Kanai, Kazuhiro P. Izawa, Masafumi Nozoe, Hiroki Kubo, Miki Kobayashi, Akira Onishi, Kyoshi Mase, Shinichi Shimada January 11, 2019

Background: Although there are reports on the promotion of physical activity during hospitalization, there is no evidence that promoting in-hospital physical activity continues over time after discharge. The purpose of this study was to evaluate the long-term effect of promoting in-hospital physical activity on postdischarge physical activity and self-efficacy for physical activity in patients with mild ischemic stroke.… Read More...

Takuma Nakashima, Takao Kojima, Norikazu Hatano, Syuntaro Takasu, Yutaro Fuse, Yukio Seki January 11, 2019

Background: Intracranial arterial stenosis (ICAS) is an important cause of ischemic stroke worldwide due to its higher risk of recurrence with medical therapy. Although some large randomized studies failed to show the superiority of surgical treatment compared with medical therapy, the results of medical therapy are not sufficient.… Read More...

Rebecca Pollard, Michelle Leppert, Charles Rawson, Mitchell Boehnke, Justin Honce, Lidia Nagae, Sharon Poisson, Eric Nyberg January 11, 2019

Background: With newly-extended treatment windows for endovascular therapy in emergent large vessel occlusions, it is increasingly important to identify thrombectomy-eligible patients without overwhelming resources dedicated to acute stroke care. We devised a simple paradigm to classify patient’s presenting neurologic symptoms to screen for large vessel occlusions.… Read More...

Alexander E. Merkler, Javid Alakbarli, Gino Gialdini, Babak B. Navi, Santosh B. Murthy, Parag Goyal, Jiwon Kim, Richard B. Devereux, Monika M. Safford, Costantino Iadecola, Hooman Kamel, Jonathan W. Weinsaft January 11, 2019

Background: The short-term risk of ischemic stroke in patients with left ventricular (LV) thrombus identified via delayed-enhancement cardiac magnetic resonance (DE-CMR) imaging is uncertain. Methods: We performed a retrospective cohort study of patients who underwent DE-CMR for evaluation of LV systolic dysfunction at NewYork-Presbyterian Hospital/Weill Cornell between 2007 and 2016.… Read More...

Rie Akaho, Ichiro Deguchi, Hiroshi Kigawa, Katsuji Nishimura January 9, 2019

Background: Cases of obsessive-compulsive disorder (OCD) following cerebrovascular accident (CVA) have rarely been reported. Methods: Case report and literature review. Results: We describe the case of a 58-year-old, right-handed man developed OCD 17 months after stroke resulting from lesion of the right middle cerebral artery infarction.… Read More...

Rachel Abdo, Halim Abboud, Pascale Salameh, Taghrid El Hajj, Hassan Hosseini January 9, 2019

Background: Despite efforts to reduce stroke mortality rates, the disease remains a leading cause of death in Lebanon highlighting the importance of understanding risk factors and subsequent mortality. We examined mortality rates during the first year after acute stroke and the major short-term (1-month) and long-term (1-year) mortality predictors.… Read More...

Xuyou Zhou, Dongmei Zhang, Yong Zhou, Fang Wang, Xiangyang Zhu January 9, 2019

Microembolic signals (MES) and insulin resistance (IR) is common in patients with acute ischemic stroke (AIS). Patients with active MES tend to be more seriously ill and prone to aggravating disease progression. IR is an important risk factor for stroke which has been found to be associated with the severity of stroke.… Read More...

WenWen Zhang, Skye Coote, Tanya Frost, Helen M. Dewey, Phillip M. Choi January 9, 2019

Background: Premorbid functional status is an important factor in acute stroke treatment decision making. Determining the modified Rankin Score (mRS) accurately may be difficult due to deficits from stroke and lack of collateral information in the acute setting. Data on the reliability of the premorbid mRS in “real-world” practice outside of clinical trial or registry settings are limited.… Read More...

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