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Alzheimer’s disease

Dementia
Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Cognitive Impairment Detection Cognitive impairment represents a spectrum of conditions that affect an individual’s cognitive …

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Traumatic brain injury
Gliatilin in the Treatment of Cognitive Impairments Not Reaching the Level of Dementia: Meta-Analysis and Systematic Review

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Study Overview The focus of the research is on Gliatilin, a choline alfoscerate compound, recognized …

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Dementia
Regional cortical network atrophy predicts progression to dementia in the Lewy body diseases

by myneuronews December 7, 2025

by myneuronews December 7, 2025

Cortical Network Atrophy and Dementia The condition known as dementia can manifest through various neurodegenerative …

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Dementia
Differential microglial responses to structurally distinct alpha-synuclein polymorphs

by myneuronews December 6, 2025

by myneuronews December 6, 2025

Differential Responses of Microglia Microglia, the resident immune cells of the central nervous system, exhibit …

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Dementia
Regional disparities of antidementia drug treatment in Germany: what can we learn for the new generation of Alzheimer’s therapies

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Antidementia Drug Treatment Patterns Antidementia medications are primarily designed to manage symptoms associated with cognitive …

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Dementia
Assessing the health-related quality of life in informal caregivers of Alzheimer’s Disease: evidence from Malaysia

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Health-Related Quality of Life in Caregivers The health-related quality of life (HRQoL) among informal caregivers …

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Traumatic brain injury
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Genetic Factors in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant public health …

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Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

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Dementia
The CSF Levels of Mitochondrial Phosphoenolpyruvate Carboxykinase 2 as a Novel Biomarker in Alzheimer’s Disease

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The research focuses on the role of mitochondrial phosphoenolpyruvate carboxykinase 2 (PEPCK-M) levels …

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Dementia
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Overview The research focused on understanding the intricate relationship between brain network connectivity and …

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Subjective symptoms of functional/dissociative seizures and their diagnostic value: A systematic review
Study Overview The research conducted offers a comprehensive examination of the subjective symptoms associated with…
Patient Perspective: Closing the Gap: Personal and Clinical Reflections on Functional Neurologic Disorder
Patient Experience The journey of individuals dealing with functional neurologic disorder (FND) is often marked…
Is It Psychogenic Non-Epileptic Event, Sleep Related Rhythmical Movement Disorder or Hypermotor Seizure?
Diagnostic Criteria To accurately identify psychogenic non-epileptic events (PNEE), sleep-related rhythmical movement disorders (RMD), and…
Downregulation of neuronal DRD2 drives microglia synaptic pruning and results in cognitive deficits by promoting CCL2 release in a rat model of chronic migraine
Study Overview This research investigates the role of dopamine receptor D2 (DRD2) in neurons and…
A videoconferencing group-based psychoeducation for family caregivers of people living with dementia: a feasibility study
Study Overview This study explored the feasibility of conducting videoconferencing group-based psychoeducation specifically tailored for…

Benchmarking mobilization practice and functional outcomes in traumatic brain injury patients admitted to the intensive care unit: a three-year service evaluation
CONCLUSION: Acute TBI patients admitted to the ICU at our institution had low rates of mobilization and achieved low levels of mobility at ICU discharge. This service evaluation highlights the need for prospective studies into early mobilization practices in the neurotrauma ICU.
Cognitive and neurobehavioral phenotypes of post 9/11 veterans with epilepsy and mild traumatic brain injury
INTRODUCTION: Traumatic brain injury (TBI) and epilepsy are significant health concerns among the veteran population, but the links between mild TBI and cognitive and behavioral changes in epilepsy have been little explored. This study leveraged natural language processing of medical records and chart review to assess the prevalence and patterns of cognitive and behavioral symptoms […]
Resting-state EEG and machine learning to investigate cortical connectivity as a biomarker in chronic mTBI
INTRODUCTION: Mild traumatic brain injury (mTBI) is a heterogeneous condition with long-term sequelae, yet diagnosis in the chronic stage remains limited by reliance on acute criteria and subjective reports. Objective biomarkers are needed, as current blood-based markers show diagnostic value primarily in the acute and subacute phases. Resting-state EEG (RS-EEG) can capture large-scale network disruptions […]
Family functioning and caring for a child with acquired brain injury: a systematic review and thematic analysis
CONCLUSIONS: Family functioning after pABI can only be fully understood if multiple interconnected psychosocial and practical aspects are considered. Most included studies were of low-to-moderate quality, limiting the reliability, validity, and generalizability of the findings. Nonetheless, the conceptual model could provide a framework for understanding family functioning and enhancing outcomes for pABI.
Advancing concussion assessment for para sport athletes through the Para SCAT6 initiative
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