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Alzheimer’s disease

Dementia
Differential microglial responses to structurally distinct alpha-synuclein polymorphs

by myneuronews December 6, 2025

by myneuronews December 6, 2025

Differential Responses of Microglia Microglia, the resident immune cells of the central nervous system, exhibit …

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Dementia
Regional disparities of antidementia drug treatment in Germany: what can we learn for the new generation of Alzheimer’s therapies

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Antidementia Drug Treatment Patterns Antidementia medications are primarily designed to manage symptoms associated with cognitive …

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Dementia
Assessing the health-related quality of life in informal caregivers of Alzheimer’s Disease: evidence from Malaysia

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Health-Related Quality of Life in Caregivers The health-related quality of life (HRQoL) among informal caregivers …

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Traumatic brain injury
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Genetic Factors in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant public health …

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Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

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Dementia
The CSF Levels of Mitochondrial Phosphoenolpyruvate Carboxykinase 2 as a Novel Biomarker in Alzheimer’s Disease

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The research focuses on the role of mitochondrial phosphoenolpyruvate carboxykinase 2 (PEPCK-M) levels …

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Dementia
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Overview The research focused on understanding the intricate relationship between brain network connectivity and …

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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

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Traumatic brain injury
Bleeding Risk With Atrial Fibrillation, Prostate Cancer Screening, Alzheimer Disease, Concussion, Melanoma, Rheumatoid Arthritis

by myneuronews October 21, 2025

by myneuronews October 21, 2025

Bleeding Risk Assessment in Atrial Fibrillation Assessing the risk of bleeding in patients with atrial …

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Traumatic brain injury
Diagnostic and prognostic role of serum/plasma and CSF amyloid beta peptide levels in traumatic brain injury: a systematic review and meta-analysis

by myneuronews October 11, 2025

by myneuronews October 11, 2025

Background and Rationale Traumatic brain injury (TBI) represents a significant public health issue, with far-reaching …

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Combined Uyghur medicine, acupuncture, and rehabilitation for traumatic oculomotor nerve palsy: A case report
CONCLUSION: This case demonstrates that an integrated treatment approach combining Uyghur medicine, rehabilitation training, and acupuncture yields significant therapeutic efficacy in improving ocular motor dysfunction secondary to complex traumatic brain injury.
Paediatric Sport-Related Concussion and Hospitalisation in Australia
No abstract
Biomarkers and clinical rules for the management of mild traumatic brain injury: a narrative review
No abstract
Extracellular Vesicle-Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. Extracellular vesicles (EVs) have emerged as promising biomarkers for neurodegeneration, owing to their accessibility in bodily fluids and dynamic molecular cargo, including microRNAs (miRNAs). The last decade has seen accumulating evidence for miRNA dysregulation in […]
P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury
The pathological basis underlying mild traumatic brain injury (mTBI)-induced long-term cognitive impairment is not fully understood. It is supposed that mTBI induces residential microglia activation rather than peripheral leukocyte infiltration to promote neuroinflammation, thus triggering myelin damage as well as cognitive impairment. The transformation of microglia towards a pro-inflammatory (M1 type) or anti-inflammatory (M2 type) […]