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astrocytes

Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Traumatic brain injury
Annual level changes of serum neuronal and glial biomarkers in a German professional football club

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Study Overview The research centered on examining the variations in serum levels of neuronal and …

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Traumatic brain injury
Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Pathophysiology of Post-concussion Syndrome Post-concussion syndrome (PCS) is a complex disorder that can arise following …

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Traumatic brain injury
Widespread and cell-type-specific transcriptomic reorganization following mild traumatic brain injury

by myneuronews June 6, 2025

by myneuronews June 6, 2025

Transcriptomic Changes Induced by Injury Mild traumatic brain injury (mTBI) triggers significant changes in the …

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Headaches
Long-term outcomes in leucine-rich glioma inactivated-1 autoimmune encephalitis and associated biomarkers of inflammation and neuronal and glial injury

by myneuronews June 5, 2025

by myneuronews June 5, 2025

Long-term outcomes Long-term outcomes in patients with leucine-rich glioma inactivated-1 (LGI1) autoimmune encephalitis are a …

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Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview The research investigates the brainstem’s cellular and molecular properties in male mice, specifically …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Imaging a concussion and the ensuing immune response at the blood-brain barrier

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding the Blood-Brain Barrier The blood-brain barrier (BBB) is a highly selective permeability barrier that …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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National and subnational burden of neurological disorders in Iran, 1990 to 2021: results from the global burden of disease study 2021
Burden of Neurological Disorders in Iran The landscape of neurological disorders in Iran presents a…
Nuclear membrane disruption in neurodegenerative diseases: Emerging perspectives
Nuclear membrane function in neuronal health The nuclear membrane, or nuclear envelope, is a critical…
Cognitive impairment and altered structural connectivity after mild traumatic brain injury: A longitudinal study based on generalized q-sampling imaging
Cognitive Impairment Assessment The assessment of cognitive impairment following mild traumatic brain injury (mTBI) is…
Prevalence and Risk of Anxiety and Depression after Concussion: A TRANSCENDENT Study
Study Overview The investigation focused on the prevalence and risk factors associated with anxiety and…
Inhibition of p38 MAPK after repetitive mTBI ameliorates immune signaling and functional deficits
Study Overview This study investigates the effects of inhibiting p38 MAPK (mitogen-activated protein kinase) following…

Relationship Between Sport Specialization and Short-Term Health-Related Quality of Life in Youth Athletes After Injury
CONCLUSION: Higher level of sport specialization is not associated with worse HRQoL approximately 1 month after sport-related injury. Female athletes have worse short-term HRQoL after an injury irrespective of sport specialization level. While sex differences were statistically significant, the magnitude of differences was small.
Behavioral treatment of insomnia in active-duty service members with traumatic brain injury: study protocol for a randomized clinical trial
BACKGROUND: Traumatic brain injury (TBI) in the U.S. military can result in lasting health issues, with insomnia being a common symptom that worsens recovery, cognitive function, and performance, especially when combined with common co-occurring conditions like chronic pain, post-traumatic stress disorder (PTSD), and depression. Insomnia may be an important intervention target for managing post-concussive symptoms […]
A population-based study of traumatic brain injury incidence and mechanisms in New Zealand: 2021-2022 compared with 2010-2011
BACKGROUND: Monitoring traumatic brain injury (TBI) incidence and epidemiological patterns is important for evidence-based strategic planning, policy, prevention, and resource allocation. We revisited population-based estimates and examined patterns of TBI incidence (all ages, severities) in 2021-2022 compared with 2010-2011 in New Zealand (NZ).
Completion of massive open online course improved knowledge about traumatic brain injury globally
CONCLUSION: The Understanding TBI MOOC improved survey scores across all demographics and experiences indicating that the MOOC is an effective tool to improve knowledge about TBI in the community.
Severity of physical, emotional, and cognitive symptoms is associated with future persistence of acute post-traumatic headache attributed to mild traumatic brain injury
AimPost-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) frequently co-occurs with other physical, cognitive, and emotional symptoms. This study assessed associations between PTH improvement and these symptoms in individuals with acute headaches (APTH) and compared symptoms between those who had recently developed persistent PTH (PPTH) to those who had long-standing PPTH.MethodsThis study included […]