Tag:

biomarkers

Dementia
Unraveling sex differences in Alzheimer’s disease and related endophenotypes with brain proteomes

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Research Context The study of Alzheimer’s disease (AD) has gained considerable momentum as researchers explore …

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Movement Disorders
The prodromal individuals’ perspective on active recruitment for early detection of α-synucleinopathies

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Perspective of Prodromal Individuals The perspective of individuals in the prodromal stage of α-synucleinopathies sheds …

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Headaches
Deep learning for Parkinson’s disease classification using multimodal and multi-sequences PET/MR images

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Study Overview The research explores the application of deep learning techniques to classify Parkinson’s disease …

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Stroke
“Low-to-moderate arsenic exposure: a global systematic review of cardiovascular disease risks”

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Epidemiological Context The issue of arsenic exposure and its potential links to cardiovascular diseases is …

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Functional neurological disorders
Memory processing by hippocampal adult-born neurons

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Hippocampal Function and Adult Neurogenesis The hippocampus is a critical brain region known for its …

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Functional neurological disorders
Structural signatures of language reorganization after left hemispherotomy in patients with Rasmussen’s encephalitis

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Language Reorganization Mechanisms Language reorganization following left hemispherotomy in patients with Rasmussen’s encephalitis reveals intriguing …

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Functional neurological disorders
Choosing the right treatment for degenerative cervical myelopathy

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Overview of Degenerative Cervical Myelopathy Degenerative cervical myelopathy (DCM) is a progressive condition characterized by …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to forecast the …

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Functional neurological disorders
Improvement of functional paralysis following unexpected comatose states

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Unexpected Comatose States and Their Impact Unexpected comatose states, often arising from traumatic brain injury, …

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The Predictive Value of Heart Rate Variability for the Prognosis of Patients with Mild to Moderate Traumatic Brain Injury
CONCLUSION: HRV can be used as an independent predictor of unfavorable prognosis in patients with TBI. Including the SDNN index in prognostic models helps to effectively predict the prognosis of adult patients with TBI.
Aldehydic load as an objective imaging biomarker of mild traumatic brain injury
Mild traumatic brain injury (mTBI) is neurological impairment induced by biomechanical forces without structural brain damage, currently without an objective diagnostic tool. Downstream injury stems from oxidative damage leading to the production of neurotoxic aldehydes. A collagen-based 3D corticomimetic in vitro model of concussion was developed, confirming aldehyde production following impact. Total aldehyde levels were […]
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures
Service members and law enforcement personnel are frequently exposed to blast overpressure during training and combat due to the use of heavy weaponry such as large-caliber rifles, explosives, and ordnance. The cumulative effects of these repeated low-level (
Plasma levels of biomarkers associated with vasodilation and neuroinflammation in pediatric patients with head trauma and their relationship with clinical characteristics of patients
CONCLUSION: Evaluation of pediatric patients with head trauma together with these neuropeptides may provide great benefits in deciding whether to perform radiography such as CT. However, due to the relatively low sensitivities in ROC analysis and small sample size, further studies are warranted before they may be used as a screening test to distinguish CT-positive […]
Trajectories of fear avoidance behavior and recovery after mild traumatic brain injury: Findings from the Toronto Concussion Study
CONCLUSION: Early fear avoidance behavior often decreases, but when it does not, it is associated with worse recovery from mTBI. These findings may inform the timing and design of interventions targeting fear avoidance behavior in patients with mTBI. (PsycInfo Database Record (c) 2025 APA, all rights reserved).