Tag:

biomarkers

Functional neurological disorders
Pyruvate Dehydrogenase Kinase 4 Underlies the Metabolic Disorder of Cardiomyocytes in Patients With Hypertrophic Cardiomyopathy From Hypertrophy to Heart Failure

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Metabolic Alterations in Cardiomyocytes In the realm of cardiology, understanding the changes that occur in …

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Functional neurological disorders
Hypoxia Alters miRNAs Levels Involved in Non-Mendelian Inheritance of Autism Spectrum Disorder in Mice

by myneuronews July 28, 2025

by myneuronews July 28, 2025

Hypoxia and Its Effects on miRNAs Hypoxia, a condition characterized by insufficient oxygen supply, has …

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Functional neurological disorders
GSAformer: Group sparse attention transformer for functional brain network analysis

by myneuronews July 27, 2025

by myneuronews July 27, 2025

Methodology Overview The study introduced GSAformer, a novel model designed to improve the analysis of …

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Dementia
Cortical inhibitory and facilitatory alterations in the continuum of alpha-synucleinopathies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Cortical Inhibition in Alpha-Synucleinopathies Alterations in cortical inhibition have been observed in alpha-synucleinopathies, which include …

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Functional neurological disorders
Polycystic ovary syndrome as a risk factor for cancer

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Understanding Polycystic Ovary Syndrome Polycystic Ovary Syndrome (PCOS) is a complex hormonal disorder that affects …

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Functional neurological disorders
Disease Progression in Children With Friedreich Ataxia: Functional Performance and Other Outcome Assessments in the FACHILD Study

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Disease Characteristics and Symptoms Friedreich ataxia is a hereditary degenerative disorder primarily affecting the spinal …

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Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging findings in Wilson’s disease reveal significant alterations in brain …

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Functional neurological disorders
Successful Treatment of Functional Neurologic Symptom Disorder (Conversion Disorder) With Subdissociative Dose Ketamine in the Emergency Department

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Effectiveness of Ketamine in FND Treatment In the realm of treating Functional Neurologic Symptom Disorder …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging plays a crucial role in understanding Wilson’s disease, a …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Pediatric concussion characteristics differ based on age
CONCLUSIONS: The results build on previous studies showing that younger pediatric patients sustain concussions mostly from non-sports mechanisms and endorse fewer symptoms which could be due to lower severity of injury and/or primarily relying on parent reporting of observable concussion symptoms. Pediatric concussion mechanism and presentation differ across ages, emphasizing the importance of age-appropriate symptom […]
Mild traumatic brain injury and concussion and persisting post-concussion symptoms: new guidelines to support evidence-based assessment and management in Australia and Aotearoa New Zealand
No abstract
Examining Clinic-Based Healthcare Utilization Patterns in a Specialty Concussion Care Setting
CONCLUSIONS: Initiation of concussion care within one week of injury demonstrates comparable effectiveness regardless of exact timing, although early presentation favors single-provider management while later presentation requires enhanced interdisciplinary coordination.
Evaluating Diagnostic Strategies for Pediatric Traumatic Brain Injury: A Literature-Based Clinical Decision Analysis
CONCLUSIONS: Application of CDA to pediatric TBI demonstrates the potential value of biomarker integration in improving diagnostic accuracy and optimizing CT utilization. Biomarker-augmented strategies may enhance patient safety by reducing unnecessary radiation exposure, while maintaining sensitivity for clinically important injuries. Prospective validation and real-world implementation studies are needed to confirm clinical effectiveness and cost-effectiveness.
Isolated oculomotor nerve palsy following mild traumatic brain injury: diagnostic challenges and insights from High-Resolution MRI
CONCLUSIONS: High-resolution CE-MRI proves instrumental in diagnosing isolated ONP in mild TBI patients, even without conventional radiological indicators. Early imaging and intervention may improve recovery outcomes. This study underscores the significance of including CE-MRI in evaluation protocols for ONP. It highlights the importance of further research to unravel the underlying pathophysiology and optimize therapeutic approaches […]