Tag:

biomarkers

Dementia
Discrepancies between CSF biomarker and PET determinations of elevated brain amyloid and their prognostic significance

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Study Overview The ongoing challenge of accurately diagnosing Alzheimer’s disease and other neurodegenerative conditions has …

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Traumatic brain injury
Reconsidering cognitive outcome one year after mild traumatic brain injury: Secondary analysis of TRACK-TBI data

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Cognitive Outcomes Post-Injury Mild traumatic brain injury (mTBI) can lead to a range of cognitive …

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Functional neurological disorders
Intracranial directed connectivity links subregions of the prefrontal cortex to major depression

by myneuronews July 8, 2025

by myneuronews July 8, 2025

Study Summary The study investigated the directed connectivity between subregions of the prefrontal cortex and …

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Traumatic brain injury
New Diagnostic Criteria for Mild Traumatic Brain Injury: Medical-Legal Considerations

by myneuronews July 7, 2025

by myneuronews July 7, 2025

New Diagnostic Framework The evolution of understanding mild traumatic brain injury (mTBI) has led to …

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Traumatic brain injury
Effects of interval exercise and diurnal variation on blood biomarkers for sport-related concussion: A crossover cohort study

by myneuronews July 5, 2025

by myneuronews July 5, 2025

Study Overview This research investigates how different exercise intervals and time of day impact blood …

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Dementia
Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The study examines the potential for machine-learning techniques to identify a reliable protein …

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Traumatic brain injury
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The research investigates the efficacy of two biological markers, S100B protein levels in …

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Traumatic brain injury
Reply: Concussions Are Associated With Increases in Blood Pressure and Cardiovascular Risk in American-Style Football Athletes

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Association Between Concussions and Blood Pressure The relationship between concussions and changes in blood pressure …

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Traumatic brain injury
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview This research investigates the roles of plasma and salivary concentrations of S100B protein …

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Functional neurological disorders
Unveiling cortical criticality changes along the prodromal to the overt continuum of alpha-synucleinopathy

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical Criticality in Alpha-Synucleinopathy The concept of cortical criticality refers to the brain’s ability to …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Pediatric concussion characteristics differ based on age
CONCLUSIONS: The results build on previous studies showing that younger pediatric patients sustain concussions mostly from non-sports mechanisms and endorse fewer symptoms which could be due to lower severity of injury and/or primarily relying on parent reporting of observable concussion symptoms. Pediatric concussion mechanism and presentation differ across ages, emphasizing the importance of age-appropriate symptom […]
Glymphatic system and mild traumatic brain injury: a mini review
Since the discovery of the glymphatic system in 2012, research on this brain-wide fluid exchange pathway has focused on understanding its role in different neurological diseases. Mild traumatic brain injury (mTBI) is a prevalent, yet often undiagnosed, condition that increases the risk of developing debilitating neurodegenerative diseases. mTBI may lead to impaired glymphatic system function […]
Subtle ocular motor deficits in people with chronic whiplash associated disorder compared to healthy controls
INTRODUCTION: More than 50% of people who are diagnosed with whiplash-associated disorder (WAD) will report symptoms 12 months and beyond after their initial onset. However, many signs and symptoms, such as dizziness, emotional lability, confusion, ocular movement abnormalities, and balance deficits, may not be directly attributed to the cervical spine and may be more consistent […]
Symptom burden in the first four years following hospitalization after mild traumatic brain injury
CONCLUSIONS: Clinicians should be alert to the long-term presence of multiple symptoms following hospitalization after mTBI, as these affect a significant proportion of individuals and are associated with poorer outcomes.
Neither American Football Playing Position Nor Total Years Playing Football Are Associated with Neurobehavioral Health Outcomes: An NFL-LONG Study
Years playing American football and primary playing position are often used to estimate concussion exposure. We examined associations between playing position and total years played with concussion history and neurobehavioral outcomes among former (N = 1544) National Football League players in the NFL-LONG study. Outcomes included the PROMIS Cognitive, Depression, and Anxiety T-scores, and Neuro-QOL […]