Tag:

biomarkers

Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Traumatic brain injury
A systematic review and meta-analysis of sleep following mild traumatic brain injury: A synthesis of the literature according to age and time-since-injury

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Effect of Age on Sleep Post-Injury The relationship between age and sleep disturbances following a …

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Dementia
Unraveling sex differences in Alzheimer’s disease and related endophenotypes with brain proteomes

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Research Context The study of Alzheimer’s disease (AD) has gained considerable momentum as researchers explore …

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Headaches
Deep learning for Parkinson’s disease classification using multimodal and multi-sequences PET/MR images

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Study Overview The research explores the application of deep learning techniques to classify Parkinson’s disease …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Traumatic brain injury
Cyclosporine A Accelerates Neurorecovery Transcriptional Trajectory in a Swine Model of Diffuse Traumatic Brain Injury

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The exploration of neurorecovery following traumatic brain injury (TBI) has gained significant attention …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to forecast the …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to predict the …

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Admission blood glucose and neutrophil-to-lymphocyte ratio for differentiating CT-positive from CT-negative mild traumatic brain injury
This study aimed to assess the diagnostic utility of routine laboratory biomarkers in adults with mTBI. We conducted a prospective study of patients who were admitted to the neurosurgical department with mTBI, had admission laboratory data available, and a brain CT scan was performed. The cohort included 101 patients (mean age: 59 ± 23.14 years). […]
Bidirectional Relationship Between Mental Health and Sports Injury in Adolescents: A Systematic Review and Meta-analysis
CONCLUSIONS: We found evidence for a bidirectional relationship between sports injuries and mental health in adolescent athletes. Further research is needed to elucidate the mechanisms underlying this relationship. Early interventions focusing on supporting mental health after sports injury, and addressing pre-existing mental health issues to reduce the risk of subsequent injury, should be tailored towards […]
Does Timing of Concussion in Season Affect Incidence and Recovery in Division I Collegiate Football Players? A CARE Consortium Study
CONCLUSIONS: In a multi-institution cohort of collegiate football players, preseason resulted in the highest incidence of concussions, while early and late-season concussions had significantly longer time to SR compared to preseason. These temporal patterns suggest that contextual factors may influence concussion outcomes and warrant mechanistic investigation to inform future management strategies.
Ultra-high contrast MRI of the brain and spinal cord using directly acquired and synthetic BipoLAr Inversion Recovery (BLAIR) images
Ultra-high contrast (UHC) magnetic resonance imaging (MRI) is a term used to describe magnetic resonance (MR) imaging that shows abnormalities with high contrast when little or no abnormality is seen on common conventional state-of-the-art MR images. It is achieved without the use of increased static or gradient magnetic fields. UHC can be accomplished by using […]
Functional Magnetic Resonance Imaging (fMRI) and Music Therapy for Concussion: A Case Report
Effective treatments for mild traumatic brain injury (mTBI) are limited and are insufficient to address patient symptoms and recovery. We report a case of an mTBI patient with debilitating visual symptoms who experienced profound symptom relief and increased functional capacity after music therapy (MT) (passive listening to specific music pieces). After other mTBI patients reported […]