Tag:

blood-brain barrier

Stroke
The effects of radiation therapy on the brain: implications for management

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Effects of Radiation Therapy on Brain Function Radiation therapy, a common treatment modality for various …

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Headaches
A rare neurological odyssey: Gastric adenocarcinoma and leptomeningeal carcinomatosis – A Peruvian case study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Case Presentation A 56-year-old male presented to the hospital with a complex clinical history, including …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Functional neurological disorders
The early-life gut microbiome in common pediatric diseases: roles and therapeutic implications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Early-life gut microbiome and pediatric diseases The human gut is populated by trillions of microorganisms, …

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Traumatic brain injury
Widespread and cell-type-specific transcriptomic reorganization following mild traumatic brain injury

by myneuronews June 6, 2025

by myneuronews June 6, 2025

Transcriptomic Changes Induced by Injury Mild traumatic brain injury (mTBI) triggers significant changes in the …

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Traumatic brain injury
Erratum: Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Study Overview The research presented focuses on the development and validation of an advanced animal …

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Traumatic brain injury
Sex-dependent blood-brain barrier alterations following repeated mild blast traumatic brain injury at varying inter-injury intervals

by myneuronews June 1, 2025

by myneuronews June 1, 2025

Study Overview The investigation focused on the impact of repeated mild blast traumatic brain injuries …

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Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Biodegradable Dendrimers: A Novel Approach Dendrimers are highly branched molecules that can be customized at …

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Stroke
Novel Perivascular Macrophage Mechanism to Promote Glymphatic Abeta Clearance After Stroke

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Mechanism of Glymphatic Clearance The glymphatic system is a unique network that plays a pivotal …

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Traumatic brain injury
Genome-wide analysis of lncRNA m6A methylation in the mouse cortex after repetitive mild traumatic brain injury

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Background on lncRNA and m6A Methylation Long non-coding RNAs (lncRNAs) are an intriguing class of …

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Subcutaneous Botulinum Toxin Type-A Injections for the Treatment of Central Neuropathic Pain in a Patient With Multiple Sclerosis – A Case Report
Study Overview This case report examines the application of subcutaneous injections of botulinum toxin type…
Homozygous COQ9 mutation: a new cause of potentially treatable hereditary spastic paraplegia
Study Overview The research investigates the role of homozygous mutations in the COQ9 gene as…
Trends in acute care of cerebrovascular events- a joinpoint analysis with German hospital data from 2000 to 2021
Cerebrovascular Event Trends The prevalence and incidence of cerebrovascular events, commonly known as strokes, have…
Gepants in Primary Care: A Targeted Approach to Acute and Preventive Treatment of Migraine
Gepants Mechanism of Action Gepants are a novel class of oral medications specifically designed to…
Targeting cognitive aging with curcumin supplementation: A systematic review and meta-analysis
Study Overview The systematic review and meta-analysis centered on curcumin supplementation aimed to investigate its…

Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods
Military service members (SMs) and veterans who have sustained one or more concussions during their service have significantly higher rates of persistent depressive symptoms and suicidality compared to non-injured peers. Despite over 500,000 SMs who have sustained concussions, there are currently no Level I evidence-based treatments for improving depressive symptoms associated with concussion. Accelerated intermittent […]
Dietary Intake of n-3 Polyunsaturated Fatty Acids Prior to a Mild Traumatic Brain Injury Demonstrates a Dose-Response Effect for Neuroprotective Benefits in Male C57BL/6 Mice
CONCLUSIONS: Overall, these results show that dietary n-3 PUFA confer neuroprotective benefits in mice resulting in significantly improved functional outcomes. This work is relevant to clinical practitioners, athletes, and the general population who aim to support their neurological health through dietary or supplementary n-3 PUFA.
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared to Orthopedic Injury
CONCLUSIONS AND RELEVANCE: BDNF DNAm appears to differ in children with TBI vs OI, particularly in the acute period. BDNF DNAm differences may reflect early biological responses that are specific to TBI.
Multimodal Magnetic Resonance Imaging with Mild Repetitive Head Injury in Awake Rats: Modeling the Human Experience and Clinical Condition
Mild repetitive head injury is a serious health problem with long-term negative consequences. Changes in brain neurobiology were assessed with MRI in a model of head injury designed to reflect the human experience. Rats were maintained on a reverse light-dark cycle and head impacted daily at 24 h intervals over three days while fully awake […]
Microstructural Damage Progression in the Pia-Arachnoid Complex
Traumatic brain injury is a leading cause of death and disability worldwide, with mild traumatic brain injury comprising the majority of cases. The pia-arachnoid complex (PAC), located at the brain-skull interface, plays a critical role in brain mechanics during head impacts, yet its response to mechanical loading is understudied. This study investigates the progression of […]