High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose
Study Overview The research focused on improving the delivery of bispecific antibodies to the brain. These antibodies, capable of binding […]
Vascular Contributions to Cognitive Impairment and Dementia in the United States: Prevalence and Incidence: A Scientific Statement From the American Heart Association
Vascular Contributions to Cognitive Health The relationship between vascular health and cognitive function is a critical area of study, as
Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience
Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that can often mimic other neurological
The efficacy and safety of intrathecal pemetrexed for leptomeningeal metastasis from non-small cell lung cancer: a single-arm meta-analysis of Chinese patients
Study Overview This study focuses on evaluating the effectiveness and safety of intrathecal pemetrexed in addressing leptomeningeal metastasis specifically in
Plasma levels of biomarkers associated with vasodilation and neuroinflammation in pediatric patients with head trauma and their relationship with clinical characteristics of patients
Biomarkers of Vasodilation and Neuroinflammation In recent studies focusing on pediatric patients with head trauma, specific biomarkers have emerged as
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial
Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide valuable insights regarding the presence,
Microstructural Damage Progression in the Pia-Arachnoid Complex
Microstructural Changes Observed The study of microstructural changes within the pia-arachnoid complex reveals a complex interplay of cellular and extracellular
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A rare neurological odyssey: Gastric adenocarcinoma and leptomeningeal carcinomatosis – A Peruvian case study
Case Presentation A 56-year-old male presented to the hospital with a complex clinical history, including persistent headaches, cognitive changes, and
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors
Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, driven by technological innovations and
Widespread and cell-type-specific transcriptomic reorganization following mild traumatic brain injury
Transcriptomic Changes Induced by Injury Mild traumatic brain injury (mTBI) triggers significant changes in the brain’s transcriptome, the complete set