Tag:

chronic stress

Traumatic brain injury
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis

by myneuronews January 10, 2026

by myneuronews January 10, 2026

Study Overview The investigation centers on the complex interplay between microglial activation and the body’s …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Mechanisms and Vulnerabilities in Functional Neurological Disorder

by myneuronews January 7, 2026

by myneuronews January 7, 2026

Mechanisms Underlying Functional Neurological Disorder Functional Neurological Disorder (FND) arises from a complex interplay of …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Structural brain alterations and predictors of clinical improvement in functional cognitive disorder after concussion

by myneuronews January 7, 2026

by myneuronews January 7, 2026

Structural Brain Changes in Functional Cognitive Disorder Recent studies have revealed that individuals with functional …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Primum non nocere: Endotracheal Intubation for Prolonged Functional/Dissociative Seizures in an Adolescent

by myneuronews January 5, 2026

by myneuronews January 5, 2026

Case Presentation In this case, we examine a 15-year-old adolescent presenting with recurrent functional seizures …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Functional neurological disorder: an evolutionary perspective

by myneuronews January 5, 2026

by myneuronews January 5, 2026

Evolutionary Perspectives on FND The concept of Functional Neurological Disorder (FND) can be significantly enriched …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Functional neurological disorder: an evolutionary perspective

by myneuronews January 5, 2026

by myneuronews January 5, 2026

Functional Neurological Disorder Overview Functional Neurological Disorder (FND) represents a complex interplay between neurological functioning …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Adverse life events and psychosocial stressors in functional neurological disorder: a retrospective cohort and case-control study using a large international electronic health record database

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Adverse Life Events in FND Recent investigations into Functional Neurological Disorder (FND) have highlighted a …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Adverse life events and psychosocial stressors in functional neurological disorder: a retrospective cohort and case-control study using a large international electronic health record database

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Background and Rationale Functional Neurological Disorder (FND) encompasses a range of neurological symptoms that are …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Adverse life events and psychosocial stressors in functional neurological disorder: a retrospective cohort and case-control study using a large international electronic health record database

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Adverse Life Events and FND Functional Neurological Disorder (FND) is characterized by neurological symptoms that …

Read more

0 Facebook Twitter Pinterest Email
Headaches
Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models

by myneuronews December 23, 2025

by myneuronews December 23, 2025

Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and …

Read more

0 Facebook Twitter Pinterest Email

Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]