Tag:

cognitive assessment

Traumatic brain injury
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive …

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Traumatic brain injury
Objective Markers for Diagnosing Concussions: Beyond Blood Biomarkers and the Role of Real-Time Diagnostic Tools

by myneuronews November 13, 2025

by myneuronews November 13, 2025

Diagnostic Innovations Recent advancements in concussion diagnostics have shown promise in enhancing the speed and …

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Dementia
Evolutionary sex bias in cognitive response to new environmental risk factor – PM2.5

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Study Overview The investigation into the cognitive responses influenced by PM2.5 exposure acknowledges the intricate …

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Dementia
Sex-related disparities in cognitive impairment in kidney transplant patients with kidney failure

by myneuronews October 26, 2025

by myneuronews October 26, 2025

Study Overview This research explores the cognitive impairment experiences of kidney transplant patients suffering from …

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Dementia
Apathy and cognitive decline as the first presentation of SLE-associated vascular dementia: a case report

by myneuronews October 20, 2025

by myneuronews October 20, 2025

Case Presentation A 45-year-old woman, previously healthy with no history of psychiatric or neurological disorders, …

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Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

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Traumatic brain injury
Factors Associated With Persistent Symptoms Following Mild Traumatic Brain Injury

by myneuronews October 17, 2025

by myneuronews October 17, 2025

Study Overview The investigation into the factors linked to persistent symptoms following a mild traumatic …

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Dementia
Differentiating Cognitive Challenges During Menopause Transition From Dementia: Key Considerations

by myneuronews October 11, 2025

by myneuronews October 11, 2025

Cognitive Changes During Menopause Menopause is marked by significant hormonal fluctuations, particularly the decline in …

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Traumatic brain injury
Retired contact sports athletes with cognitive concerns: promoting lifelong brain health

by myneuronews October 8, 2025

by myneuronews October 8, 2025

Understanding Cognitive Concerns in Retired Athletes Cognitive concerns in retired athletes, particularly those involved in …

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Dementia
Robust Extrapolated Semi-Solid Magnetization Transfer Reference Fitting for Quantitative Amide Proton Transfer Imaging at 3 T: Application to Patients With Mild Cognitive Impairment and Mild Dementia

by myneuronews October 3, 2025

by myneuronews October 3, 2025

Study Overview This study focuses on advancing the understanding of quantitative Amide Proton Transfer (APT) …

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Depression-like behavior following mild traumatic brain injury in adolescent rats: a role for limbic neuropeptides
Mild traumatic brain injury (mTBI) is common among adolescents because of their participation in contact sports and mTBI is more likely to lead to depression-related behaviors in girls than boys. Various neuropeptides, often within the limbic system, have been implicated in the regulation of depression-related behaviors. To identify potential neuropeptide involvement in behavioral effects of […]
Shape analysis of the amygdala, hippocampus and thalamus in former American football players
Repetitive head impacts are common in contact and collision sports and are linked to structural brain changes and an elevated risk of neurodegenerative diseases such as Chronic Traumatic Encephalopathy. Identifying early in vivo structural markers remains challenging. Although diagnosis currently requires post-mortem confirmation, clinical symptoms, including cognitive impairment and behavioural changes, are reflected in the […]
Pre- and Post-treatment Impact of Antioxidants on Astrocytic Reactive Oxygen SpeciesAn Undergraduate Classroom Research Project
Undergraduate research is a method to enhance student engagement in science courses as well as expand scientific curiosity. One method in doing so is performing course undergraduate research experiences. This project started as an undergraduate research project and expanded into a six-week in-class honor's research experience. The field of traumatic brain injury (TBI) evokes instant […]
TDP-43 dysfunction leads to impaired proteostasis and predisposes mice to worse neurological outcomes after brain injury
CONCLUSIONS: Our data demonstrate that expression of dysfunctional TDP-43 leads to deficits within the proteostasis network in vivo at baseline. Despite an upregulation of proteostasis-related genes at the transcript level in mutant TDP-43 mice after TBI, mutant TDP-43 mice exhibit an impaired response to, and recovery from, brain trauma relative to their WT counterparts. Restoring […]
Resting-state EEG and machine learning to investigate cortical connectivity as a biomarker in chronic mTBI
Mild traumatic brain injury (mTBI) is a heterogeneous condition with long-term sequelae, yet diagnosis in the chronic stage remains limited by reliance on acute criteria and subjective reports. Objective biomarkers are needed, as current blood-based markers show diagnostic value primarily in the acute and subacute phases. Resting-state EEG (RS-EEG) can capture large-scale network disruptions through […]