Tag:

concussion

Traumatic brain injury
MSC-Exosomes alleviate cognitive impairment after mild traumatic brain injury by inhibiting ferroptosis via PI3K/AKT/mTOR-mediated upregulation of GPX4

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The research investigates the potential therapeutic effects of mesenchymal stem cell-derived exosomes (MSC-Exosomes) …

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Traumatic brain injury
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive …

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Traumatic brain injury
Reaching Underserved Communities in Partnership with Outreach Athletic Trainers

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Outreach Strategies To effectively engage underserved communities, tailored outreach strategies are essential. These approaches prioritize …

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Traumatic brain injury
Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Clinical Outcomes in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant challenge in …

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Traumatic brain injury
Long intervals between repetitive concussions reduce risk of cognitive impairment and limit microglial activation, astrogliosis, and tauopathy in adolescent rats

by myneuronews November 18, 2025

by myneuronews November 18, 2025

Impact of Concussion Intervals on Cognitive Outcomes Research indicates that the timing between concussive events …

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Traumatic brain injury
C-FLAIR: Fluid-attenuated Inversion Recovery with Controlled Artifact Suppression in Brain MRI

by myneuronews November 18, 2025

by myneuronews November 18, 2025

Study Overview The research focuses on C-FLAIR, an advanced MRI technique designed to enhance the …

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Traumatic brain injury
2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila

by myneuronews November 18, 2025

by myneuronews November 18, 2025

Study Overview The investigation centers around understanding how innate immune signaling influences the outcomes of …

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Traumatic brain injury
Physiatry Reviews for Evidence in Practice (PREP) Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: “Context of Injury and Clinical Trajectories After Mild Traumatic Brain Injury”

by myneuronews November 17, 2025

by myneuronews November 17, 2025

Study Overview The research investigated the outcomes and clinical trajectories following mild traumatic brain injury …

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Traumatic brain injury
Comparison of Pre-injury and Clinical Characteristics Between Adolescents With Sport-Related Concussion and Non-Sport-Related Concussion Presenting to a Specialty Concussion Clinic

by myneuronews November 17, 2025

by myneuronews November 17, 2025

Study Overview This research aims to investigate the differences in pre-injury and clinical characteristics between …

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Traumatic brain injury
Physiatry Reviews for Evidence in Practice (PREP) Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: “Context of Injury and Clinical Trajectories After Mild Traumatic Brain Injury”

by myneuronews November 17, 2025

by myneuronews November 17, 2025

Study Overview The investigation centers on the aftermath of mild traumatic brain injuries (mTBI), specifically …

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Depression-like behavior following mild traumatic brain injury in adolescent rats: a role for limbic neuropeptides
Mild traumatic brain injury (mTBI) is common among adolescents because of their participation in contact sports and mTBI is more likely to lead to depression-related behaviors in girls than boys. Various neuropeptides, often within the limbic system, have been implicated in the regulation of depression-related behaviors. To identify potential neuropeptide involvement in behavioral effects of […]
Shape analysis of the amygdala, hippocampus and thalamus in former American football players
Repetitive head impacts are common in contact and collision sports and are linked to structural brain changes and an elevated risk of neurodegenerative diseases such as Chronic Traumatic Encephalopathy. Identifying early in vivo structural markers remains challenging. Although diagnosis currently requires post-mortem confirmation, clinical symptoms, including cognitive impairment and behavioural changes, are reflected in the […]
Pre- and Post-treatment Impact of Antioxidants on Astrocytic Reactive Oxygen SpeciesAn Undergraduate Classroom Research Project
Undergraduate research is a method to enhance student engagement in science courses as well as expand scientific curiosity. One method in doing so is performing course undergraduate research experiences. This project started as an undergraduate research project and expanded into a six-week in-class honor's research experience. The field of traumatic brain injury (TBI) evokes instant […]
TDP-43 dysfunction leads to impaired proteostasis and predisposes mice to worse neurological outcomes after brain injury
CONCLUSIONS: Our data demonstrate that expression of dysfunctional TDP-43 leads to deficits within the proteostasis network in vivo at baseline. Despite an upregulation of proteostasis-related genes at the transcript level in mutant TDP-43 mice after TBI, mutant TDP-43 mice exhibit an impaired response to, and recovery from, brain trauma relative to their WT counterparts. Restoring […]
Resting-state EEG and machine learning to investigate cortical connectivity as a biomarker in chronic mTBI
Mild traumatic brain injury (mTBI) is a heterogeneous condition with long-term sequelae, yet diagnosis in the chronic stage remains limited by reliance on acute criteria and subjective reports. Objective biomarkers are needed, as current blood-based markers show diagnostic value primarily in the acute and subacute phases. Resting-state EEG (RS-EEG) can capture large-scale network disruptions through […]