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"Insights into mTBI, PCS, and FND — One Synapse at a Time" A bit more creative, nodding to neuroscience roots while covering your full range.
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  • Functional neurological disorders

    Brain activation characteristics of schizophrenia and bipolar disorder-I patients during letter and category fluency tasks: An empirical study using functional near-infrared spectroscopy

    by myneuronews April 24, 2025
    by myneuronews April 24, 2025

    Brain Activation Patterns in Schizophrenia and Bipolar Disorder The study examined specific brain activation patterns …

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  • Functional neurological disorders

    Dystonia: pathophysiology and the role of acupuncture in treatment

    by myneuronews April 24, 2025
    by myneuronews April 24, 2025

    Understanding Dystonia and Its Mechanisms Dystonia is a complex movement disorder characterized by sustained muscle …

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  • Functional neurological disorders

    Chemical imaging delineates Aβ plaque polymorphism across the Alzheimer’s disease spectrum

    by myneuronews April 24, 2025
    by myneuronews April 24, 2025

    Aβ Plaque Polymorphism Overview Amyloid-beta (Aβ) plaques are characteristic features found in the brains of …

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  • Functional neurological disorders

    Inceptive Investigation of Audio-Visual Homogenization on Dissociative Neurological Symptoms

    by myneuronews April 21, 2025
    by myneuronews April 21, 2025

    Study Summary The study investigated the effects of audio-visual homogenization on individuals experiencing dissociative neurological …

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  • Traumatic brain injury

    The Role of the IMPACT Test in Concussion Screening and Treatment Planning

    by Ioannis Mavroudis September 28, 2024
    by Ioannis Mavroudis September 28, 2024

    Mild Traumatic Brain Injury (mTBI), commonly referred to as a concussion, has been a growing …

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  • Functional neurological disorders

    Legal and Ethical Concerns in the Diagnosis of Functional Neurological Disorders

    by Ioannis Mavroudis April 27, 2024
    by Ioannis Mavroudis April 27, 2024

    Functional Neurological Disorders (FND) are characterized by neurological symptoms that are not explained by identifiable …

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  • Functional neurological disorders

    Distinguishing Functional Neurological Disorder from Malingering or Feigning

    by Ioannis Mavroudis April 21, 2024
    by Ioannis Mavroudis April 21, 2024

    Functional Neurological Disorder (FND) presents a frontier of exploration in neurological and psychiatric disciplines, where …

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  • Medical professionalsTraumatic brain injury

    Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

    by Ioannis Mavroudis March 22, 2024
    by Ioannis Mavroudis March 22, 2024

    Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

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  • Medical professionals

    Incidence of Post-Traumatic Headaches After Mild Traumatic Brain Injury

    by Ioannis Mavroudis February 12, 2024
    by Ioannis Mavroudis February 12, 2024

    The prevalence of post-traumatic headache (PTH) following mild traumatic brain injury (mTBI) exhibits significant variability, …

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  • Sildenafil provokes headache but not migraine in men with migraine without aura: a randomized, placebo-controlled crossover trial
    Study Overview The research aimed to investigate the effects of sildenafil, a phosphodiesterase type 5…
  • Associations of Lifetime Cumulative Estrogen Exposure with Lifecourse Social Exposures, Cognitive Decline, and Dementia Risk Among Postmenopausal White, Black, and Latina Women
    Lifetime Estrogen Exposure and Cognitive Health Lifetime estrogen exposure has emerged as a significant factor…
  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Incretin Mimetics Mechanism of Action Incretin mimetics are agents that are designed to mimic the…
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Study Overview This investigation focuses on the effects of N-stearidonoylethanolamine (NSE) in addressing synaptic deficits…
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    Study Overview This study investigates the long-term effects of persistent post-concussion symptoms (PPCS) on various…

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Research

  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
  • Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
    CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
  • Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
    Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]

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