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GCS

Traumatic brain injury
The role of two brain injury biomarkers, GFAP and UCH-L1, for the management of mTBI in the Emergency Department: an observational study

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Study Overview This observational study focused on the potential role of two specific brain injury …

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Traumatic brain injury
Elevation of C-reactive protein and homocysteine levels as reliable biomarkers for assessing injury severity and prognosis in traumatic brain injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Biomarkers in Traumatic Brain Injury In the context of traumatic brain injury (TBI), biomarkers serve …

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Traumatic brain injury
Prediction of Mental Health Complications Following Mild Traumatic Brain Injury

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Impact of Mild Traumatic Brain Injury Mild traumatic brain injury (mTBI), commonly referred to as …

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Traumatic brain injury
Mild and moderate traumatic brain injury: Screening, documentation and referral to concussion services

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Understanding Mild and Moderate Traumatic Brain Injury Mild and moderate traumatic brain injuries (TBIs) represent …

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Traumatic brain injury
A new characterisation of acute traumatic brain injury: the NIH-NINDS TBI Classification and Nomenclature Initiative

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Definition and Classification of TBI Traumatic brain injury (TBI) is a complex and multifaceted condition …

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Traumatic brain injury
Cost-effectiveness of Cerebrolysin as an add-on treatment for neurorecovery after traumatic brain injury

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Cerebrolysin Overview Cerebrolysin is a proprietary neuropeptide preparation derived from porcine brain tissue, composed of …

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Traumatic brain injury
Thiamine administration and in-hospital mortality in patients with traumatic brain injury: analysis of the MIMIC-IV database

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Study Overview The research investigated the role of thiamine administration in reducing in-hospital mortality among …

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Traumatic brain injury
Thiamine administration and in-hospital mortality in patients with traumatic brain injury: analysis of the MIMIC-IV database

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Study Overview This study investigates the relationship between thiamine administration and in-hospital mortality in patients …

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Traumatic brain injury
Systematic vitamin K antagonist reversal with prothrombin complex concentrate in patients with mild traumatic brain injury: randomized controlled trial

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Background and Rationale The use of vitamin K antagonists (VKAs), such as warfarin, has become …

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Traumatic brain injury
Systematic vitamin K antagonist reversal with prothrombin complex concentrate in patients with mild traumatic brain injury: randomized controlled trial

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Study Overview The research conducted aimed to evaluate the effectiveness of prothrombin complex concentrate (PCC) …

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Understanding factors influencing the return to physical activity, perspectives of adults with concussion/mild traumatic brain injury: A qualitative study
Understanding the factors that influence the return to physical activity can help to modify behaviour to enhance the recovery of symptoms and physical activity. We conducted 14 semi-structured interviews to explore the barriers and facilitators to returning to physical activity in adults following a mild traumatic brain injury (TBI). The study design was informed by […]
Clinical Utility of the Sport Concussion Office Assessment Tool 6 (SCOAT6) and Other Select Multidomain Assessments for Subacute Sport-Related Concussion
CONCLUSIONS: The PCSI, timed tandem gait, and mVOMS components of the SCOAT6 were useful in identifying sport-related concussion. However, verbal cognitive tests, orthostatic vital signs, and clinical balance components were not useful for this purpose. The CP Screen, additional items from the full version of the VOMS, and ImPACT memory and processing speed were also […]
Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies
INTRODUCTION: Persistent post-concussion syndrome (PCS) following mild traumatic brain injury (mTBI) represents a growing global health challenge that significantly impacts patients' quality of life. Despite advances in acute concussion management, there remains a critical need for effective, evidence-based treatments for chronic PCS, as current interventions show limited success in addressing both symptoms and underlying pathophysiology.
Time-limited association between plasma transfusion and mortality in pediatric traumatic brain injury
CONCLUSION: This study reports a significant association between early plasma administration and a lower risk of 4-hour mortality among children with severe TBI that does not persist at or beyond 24 hours. While these data suggest that plasma resuscitation may extend the window for lifesaving intervention, additional prospective data are needed.
Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury
CONCLUSION: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.