Tag:

genetic predisposition

Traumatic brain injury
Resting-State Brain Activity Changes and Their Genetic Correlates in Mild Traumatic Brain Injury

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Study Overview The investigation into resting-state brain activity alterations in individuals who have experienced mild …

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Movement Disorders
Metabolic abnormalities of the cortico‑striato‑thalamo‑cortical circuit of rats with tic disorder

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Metabolic Alterations in Tic Disorders Research into tic disorders has revealed significant metabolic changes that …

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Stroke
Aortic stenosis intricacies beyond the valve: A bidirectional Mendelian randomization study

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Study Overview This study explores the multifaceted relationships surrounding aortic stenosis, a condition characterized by …

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Traumatic brain injury
Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

by myneuronews June 11, 2025

by myneuronews June 11, 2025

Study Overview This trial is meticulously designed to assess the effectiveness of a high-intensity, home-based …

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Traumatic brain injury
Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Pathophysiology of Post-concussion Syndrome Post-concussion syndrome (PCS) is a complex disorder that can arise following …

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Stroke
Effect of COMT Val158Met Polymorphism on Stroke Functional Outcome and Recovery

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Study Overview The investigation into the impact of the COMT Val158Met polymorphism on stroke functional …

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Functional neurological disorders
Recognising and managing functional neurological disorder in the acute healthcare setting

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) represents a fascinating convergence of neurology and …

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Functional neurological disorders
Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Understanding Neurodevelopmental Copy Number Variants Neurodevelopmental copy number variants (CNVs) are structural alterations in the …

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Functional neurological disorders
Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Neurodevelopmental Variants and Penetrance Neurodevelopmental copy number variants (CNVs) represent significant alterations in an individual’s …

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Functional neurological disorders
A Narrative Review of Pemphigoid Diseases: Bridging Associations, Comorbidities, and Management

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Overview of Pemphigoid Diseases Pemphigoid diseases are a group of rare autoimmune conditions primarily characterized …

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Effectiveness of disease-modifying agents in ameliorating multiple sclerosis – A cross-sectional observational study
Study Overview This research was designed to assess the efficacy of disease-modifying agents (DMAs) in…
Systemic Neisseria sicca Infection Associated With Ravulizumab Therapy in Myasthenia Gravis
Study Overview The research focuses on the implications of Ravulizumab therapy in patients suffering from…
Aortic stenosis intricacies beyond the valve: A bidirectional Mendelian randomization study
Study Overview This study explores the multifaceted relationships surrounding aortic stenosis, a condition characterized by…
Effectiveness of Instrument-assisted Soft-tissue Mobilization Versus Dry Cupping on Pain and Cervical Range of Motion in Treatment of Neck Pain
Study Overview The research compares two therapeutic techniques, instrument-assisted soft tissue mobilization (IASTM) and dry…
Metabolic abnormalities of the cortico‑striato‑thalamo‑cortical circuit of rats with tic disorder
Metabolic Alterations in Tic Disorders Research into tic disorders has revealed significant metabolic changes that…

Subsequent Emergency Department Visits in Geriatric Mild Traumatic Brain Injury: Relationship with Fall, Payor, and Discharge Outcome
Background/Objectives: Older adults (ages ≥ 65) have experienced longer recovery, decreased independence in self-care, and reduced quality of life after diagnosis of mild traumatic brain injury (mTBI). Although the sequela following mTBI has also generated higher healthcare costs in older adults, the research on associations returning to the emergency department (ED) has been limited. This […]
Resting-State Brain Activity Changes and Their Genetic Correlates in Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) often leads to persistent cognitive and emotional symptoms, but the underlying neurobiological mechanisms remain unclear. Although previous studies have reported alterations in resting-state brain activity in mTBI patients, the findings have been inconsistent, and the genetic basis of these changes has not been fully explored. A coordinate-based voxel-wise meta-analysis was […]
Depression Symptoms Associated With Clinical Symptoms, Disability, and Functional Connectivity After Traumatic Brain Injury
CONCLUSIONS: The findings suggest that depression after TBI may not be a unitary syndrome but rather may be composed of clusters of symptoms that have different associations with TBI symptom burden, disability, and brain connectivity.
The Polytrauma Clinical Triad Among Women with a History of Intimate Partner Violence
Women with a history of intimate partner violence (IPV) are at risk for traumatic brain injury (TBI) with persistent neurobehavioral symptoms, post-traumatic stress disorder (PTSD), and chronic pain, which, together, characterize the polytrauma clinical triad. Among predominantly male Veteran samples, research has suggested that the triad may exacerbate health problems, compared with the presence of […]
Understanding Beliefs and Perceptions of Parents, Coaches, and Organizational Leaders toward Non-concussive Head Impact Exposure in Youth American Football
Concussions are a prevalent public health concern; however, non-concussive head impacts without signs and symptoms of concussion may have a greater influence on brain health. The objective of this study was to apply components of the health belief model to perceptions of non-concussive head impacts and preventative efforts to reduce head impacts in youth American […]