Tag:

genetic predisposition

Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein) plays a pivotal role in the pathophysiology …

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Functional neurological disorders
Analysis of biased allelic enhancer activity of schizophrenia-linked common variants

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Biased Enhancer Activity in Schizophrenia Research in recent years has increasingly pointed to the pivotal …

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Dementia
Discrepancies between CSF biomarker and PET determinations of elevated brain amyloid and their prognostic significance

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Study Overview The ongoing challenge of accurately diagnosing Alzheimer’s disease and other neurodegenerative conditions has …

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Functional neurological disorders
A comparative study on growth, feed intake, and serum vitamin and mineral concentrations in Western white-faced rams with and without limb deformities

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Growth and Feed Intake Comparison The study focused on the growth rates and feed intake …

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Functional neurological disorders
Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Comorbid Gene Identification The identification of comorbid genes linking type 2 diabetes and migraine is …

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Dementia
Knowledge and attitudes towards Alzheimer’s disease among adult residents in Jiulongpo, Chongqing, China: A cross-sectional survey

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview This research aimed to explore the awareness and perceptions regarding Alzheimer’s disease among …

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Dementia
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to explore the role of non-coding RNAs in the development …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenesis of Myasthenia Gravis Myasthenia Gravis (MG) is an autoimmune disorder characterized by weakness and …

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Functional neurological disorders
Dynamic electro-clinical features in Guanidinoacetate N-methyltransferase deficiency: A familial case series

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Clinical Presentation and Genetic Findings The study highlights the varied clinical presentations associated with Guanidinoacetate …

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Traumatic brain injury
Resting-State Brain Activity Changes and Their Genetic Correlates in Mild Traumatic Brain Injury

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Study Overview The investigation into resting-state brain activity alterations in individuals who have experienced mild …

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Low-Value Computed Tomography for Children in the Emergency Department: A Repeated Cross-Sectional Study
CONCLUSIONS: Low-value CT use was higher among children treated in nonpediatric EDs and by nonpediatric providers. Improvement initiatives should target specific hospital types and specialties.
Influence of oxidative stress caused by a blast wave in acoustic barotrauma on the auditory analyzer
CONCLUSION: Conclusions: An imbalance of antioxidant protection led to significant microcirculatory disorders. The data obtained are important for the neutralization of the effect of damaging factors of OS on thе inner ear microcirculation.
Sleep Architecture Immediately After a Sport-Related Concussion Sustained During a Professional Rugby Union Match: A Retrospective Case Study
CONCLUSION: Acute responses after the SRC included sleep disturbances and elevated sympathetic activity (during sleep). The player had difficulty achieving deep, restorative sleep the first night following the SRC, aligning with the non-restorative-sleep complaints commonly reported by concussed athletes on the night(s) immediately following injury.
Concussion as a Public Health Crisis: Multilevel Approaches for Improving Athlete Care-Seeking
Fifty percent of athletes who suffer a concussion do not seek care for the injury, which leads to worse outcomes including more severe and numerous symptoms and prolonged recovery. Many organizations use annual education as a secondary injury-prevention strategy to improve athlete care-seeking, and subsequently, injury outcomes. However, these efforts have proven insufficient. Those who […]
Repetitive Mild Traumatic Brain Injury Disrupts Learning and Memory: A Novel Olfactory Approach to Detection
Traumatic brain injury (TBI) leads to significant public health concerns due to cognitive decline and increased risks of neurological conditions like Alzheimer's disease and chronic traumatic encephalopathy. Preclinical models are essential for exploring how mild TBI leads to neuronal dysfunction and neurodegeneration. Using a mouse model, we applied repetitive, mild, side-alternating impacts to induce rapid […]