Tag:

genetic predisposition

Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein) plays a pivotal role in the pathophysiology …

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Functional neurological disorders
Analysis of biased allelic enhancer activity of schizophrenia-linked common variants

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Biased Enhancer Activity in Schizophrenia Research in recent years has increasingly pointed to the pivotal …

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Dementia
Discrepancies between CSF biomarker and PET determinations of elevated brain amyloid and their prognostic significance

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Study Overview The ongoing challenge of accurately diagnosing Alzheimer’s disease and other neurodegenerative conditions has …

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Functional neurological disorders
A comparative study on growth, feed intake, and serum vitamin and mineral concentrations in Western white-faced rams with and without limb deformities

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Growth and Feed Intake Comparison The study focused on the growth rates and feed intake …

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Functional neurological disorders
Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Comorbid Gene Identification The identification of comorbid genes linking type 2 diabetes and migraine is …

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Dementia
Knowledge and attitudes towards Alzheimer’s disease among adult residents in Jiulongpo, Chongqing, China: A cross-sectional survey

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview This research aimed to explore the awareness and perceptions regarding Alzheimer’s disease among …

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Dementia
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to explore the role of non-coding RNAs in the development …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenesis of Myasthenia Gravis Myasthenia Gravis (MG) is an autoimmune disorder characterized by weakness and …

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Functional neurological disorders
Dynamic electro-clinical features in Guanidinoacetate N-methyltransferase deficiency: A familial case series

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Clinical Presentation and Genetic Findings The study highlights the varied clinical presentations associated with Guanidinoacetate …

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Movement Disorders
Restless legs syndrome in pregnancy: A systematic review of prevalence

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Prevalence of Restless Legs Syndrome Restless Legs Syndrome (RLS) during pregnancy is a condition that …

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Controversies in the diagnosis of chronic inflammatory demyelinating polyneuropathy
Understanding Chronic Inflammatory Demyelinating Polyneuropathy Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is characterized by a progressive…
Interferon alfa and beta receptor confers resistance against Neospora caninum infection in mice
Study Overview This investigation focuses on the interaction between interferon-alfa and -beta receptors and their…
Advances and challenges in experimental models of posttraumatic epilepsy for therapeutic interventions
Experimental Models of Posttraumatic Epilepsy Research into posttraumatic epilepsy (PTE) has benefited significantly from various…
Anti-NMDA receptor encephalitis following SARS-CoV-2 infection in children
Study Overview The study investigates the neurological complications associated with anti-NMDA receptor encephalitis in pediatric…
Insights From a Mixed Methods Analysis of 3 Health Technologies Used in Patients With Parkinson Disease: Mixed Methods Study
Study Overview The research presented a comprehensive examination of three distinct health technologies utilized by…

Interpreting Change in Sport Concussion Assessment Tool-5th Edition (SCAT5) Scores in National Rugby League Women's Premiership Players
CONCLUSION: SCAT5 scores had low to moderate test-retest reliability across a one-year period. Reliable change scores for the SCAT5 were developed in this study for use with professional women rugby league players. When evaluating post-injury SCAT5 scores, it can be helpful to consider both what the score means compared to normative reference values and compared […]
An update on paediatric traumatic brain injury in the emergency department: a narrative review
Traumatic brain injury (TBI) affects an estimated 330,000 to 500,000 children annually in England and Wales and represents a significant burden on healthcare systems. Presentations range from mild to severe, and each case presents unique challenges to the Emergency Department (ED) clinicians. Most paediatric TBIs are mild, and several validated clinical decision rules (CDRs) such […]
The effect of neck strength and anthropometric properties on the linear and rotational accelerations experienced by academy footballers during heading: an exploratory analysis
CONCLUSION: Neck strength and anthropometric factors showed mixed associations with head accelerations during heading, explaining a small proportion of the variance in linear and rotational accelerations.
Ultra-early detection of S100B biomarkers using a nanophotonic biosensor with deep learning quantification: A clinical model based on EDAS patients
CONCLUSION: This biosensor-AI platform enables rapid (
An Analysis of Guardian Cap Use and Changes in the Concussion Rate in National Football League Preseason Practices From 2018 to 2023
CONCLUSION: Required use of the Guardian Cap NXT was associated with a 54% to 62% reduction in the overall incidence of NFL practice concussions. However, when only concussions involving a helmet shell impact were considered, there was no longer a significant relationship between Guardian Cap NXT use and the incidence of concussions.