Tag:

genetic predisposition

Functional neurological disorders
Increased Prevalence of an Oxytocin Receptor Gene Variant in Functional Neurological Disorder: A Case-Control Study

by myneuronews September 19, 2025

by myneuronews September 19, 2025

Genetic Associations with FND In recent years, increasing attention has been placed on the genetic …

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Dementia
Polygenic risk score of Alzheimer’s disease is associated with cognitive trajectories and phenotypes of cerebral organoids

by myneuronews September 17, 2025

by myneuronews September 17, 2025

Study Overview This study investigates the relationship between polygenic risk scores (PRS) for Alzheimer’s disease …

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Headaches
Subtype shift, relapse rate and risk factors of frequent relapse in cluster headache: A multicenter, prospective, longitudinal observation

by myneuronews September 13, 2025

by myneuronews September 13, 2025

Study Overview The study focused on understanding the various types of cluster headaches, examining the …

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Traumatic brain injury
Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview This research focuses on the cellular mechanisms involved in concussive injuries, specifically examining …

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Traumatic brain injury
Boston University Alzheimer’s Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer’s disease and related dementias

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Research Objectives The primary aim of the Boston University Alzheimer’s Disease Research Center’s Clinical Core …

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Functional neurological disorders
Unraveling functional neurological disorder in pediatric populations: A systematic review of diagnosis, treatment, and outcomes

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Understanding Functional Neurological Disorder in Children Functional Neurological Disorder (FND) in pediatric populations represents a …

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Traumatic brain injury
Influence of oxidative stress caused by a blast wave in acoustic barotrauma on the auditory analyzer

by myneuronews August 23, 2025

by myneuronews August 23, 2025

Impact of Oxidative Stress Oxidative stress is a condition characterized by an imbalance between the …

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Traumatic brain injury
Symptom Trajectories and Their Biopsychosocial Correlates in Pediatric Concussion: An A-CAP Study

by myneuronews August 8, 2025

by myneuronews August 8, 2025

Symptom Trajectories Understanding the dynamics of symptom trajectories in pediatric concussion is essential for identifying …

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Functional neurological disorders
Malignant catatonia in an adolescent with pogo transposable element derived with zinc finger domain (POGZ) gene mutation: case report

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Case Presentation In this case, we present a 16-year-old adolescent who exhibited symptoms consistent with …

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Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Role of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …

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Imported Familial Pulmonary and Cerebral Paragonimiasis in Korea: Cases and Literature Review from a Clinical Grand Round Conference
Study Overview The investigation into familial pulmonary and cerebral paragonimiasis in Korea highlights the challenges…
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model
Study Overview The research focuses on the role of GASDERMIN D in the context of…
Patient-reported outcomes and acceptability of suggestion and hypnosis-based therapy for functional neurological disorder within an NHS service
Patient-Reported Outcomes In examining the results derived from patient-reported outcomes, it is essential to highlight…
Language biomarker screening using AI: a transdiagnostic approach to brain
Language Biomarkers in AI Research Language biomarkers are pivotal in utilizing artificial intelligence for assessing…
Morning sleep inertia and its associated factors: Findings from a nationwide study
Understanding Sleep Inertia Sleep inertia refers to the temporary state of cognitive and physical impairment…

Visualizing and Quantifying Impact with Mechanochromic Sensing Paints Based on Self-Assembled Polydiacetylene-Silk Core-Shell Vesicles
Rapid detection and quantification of mechanical impact on surfaces is relevant for many fields, as it enables monitoring of material stresses and integrity or to assess the physiological effects of force on humans for concussions, gait, or blast dosimetry, among others. Accurate and quantitative detection of impact force, especially at high values (100-770 N), is […]
Acute Traumatic Intracerebral Hematoma: To Operate or Not to Operate?
Acute traumatic intracerebral hematoma (TICH) is a severe complication of head injury, often associated with high morbidity and mortality. We report the case of a 44-year-old man admitted to the ED after a craniocerebral trauma caused by a fall from a tractor. On admission, he presented with impaired consciousness, scoring 8 on the Glasgow Coma […]
The clinical rollout of a novel intervention for Veterans with persistent post-concussive symptoms: Protocol for a pragmatic 2-site trial of On-TRACC
BACKGROUND AND OBJECTIVES: Veterans with a history of mild traumatic brain injury (mTBI) often report persistent post-concussive symptoms (PPCS). Clinical care guidelines recommend psychoeducation as well as assessment and treatment of the prevalent comorbid psychiatric, sleep, and pain conditions known to contribute to and amplify PPCS. The purpose of this site-randomized pragmatic trial is to […]
Relevance of cerebral microbleeds with leaky blood brain barrier in traumatic brain injury and protective role of interferon-gamma: A cohort study
OBJECTIVES: Cerebral microbleeds (CMBs), which present as foci of hypointensities on T2*-weighted Magnetic Resonance Imaging (MRI) are associated with weakened vessel walls. CMBs are also a frequent finding in traumatic brain injury (TBI) in association with poor outcome. We investigated whether a combination of susceptibility weighted imaging (SWI) and dynamic contrast enhanced (DCE) MRI could […]
Language biomarker screening using AI: a transdiagnostic approach to brain
Individuals with left-hemisphere damage (LHD), right-hemisphere damage (RHD), dementia, mild cognitive impairment (MCI), traumatic brain injury (TBI), and healthy controls are characterized by overlapping clinical profiles affecting communication and social interaction. Language provides a rich, non-invasive window into neurological health, yet objective and scalable methods to automatically differentiate between conditions with are lacking. This method […]