Basic Science and Pathogenesis
Understanding Pathogenesis Pathogenesis refers to the intricate mechanisms through which diseases develop and progress within the body. It encompasses the […]
Basic Science and Pathogenesis Read Post »
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a comprehensive exploration of biomarker and
Neuronal and Glial Biomarkers in Urine of Athletes with Different Risks of Head Trauma to Monitor Sports-Related Concussions
Biomarkers in Urine The detection of biomarkers in urine has emerged as a promising method for assessing neural injury, particularly
A study on the association of apolipoprotein E with oxidative stress markers, neurological function, and cognitive impairment following traumatic brain injury
Association of Apolipoprotein E and Oxidative Stress Apolipoprotein E (ApoE) plays a crucial role in lipid metabolism and neuronal repair,
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective
Background on Genetic Frontotemporal Dementia Genetic frontotemporal dementia (FTD) is a group of neurodegenerative disorders characterized by progressive changes in
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery
Genetic Factors in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant public health challenge, and the severity of
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice
Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been identified as a significant factor
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum
Study Overview The research focused on understanding the intricate relationship between brain network connectivity and gene expression profiles in individuals
Unexpected genomic architecture in a sporadic case of C1-INH Hereditary Angioedema: the hidden heritability
Genomic Architecture Insights The genomic architecture in individuals with C1-INH Hereditary Angioedema (HAE) showcases a complex interplay of genetic variations
A Comprehensive Approach to the Assessment and Management of Posttraumatic Headache
Overview of Posttraumatic Headache Posttraumatic headache (PTH) is a prevalent and often debilitating disorder that can emerge following a traumatic
A Comprehensive Approach to the Assessment and Management of Posttraumatic Headache Read Post »