Tag:

genetic predisposition

Functional neurological disorders
Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Comorbid Gene Identification The identification of comorbid genes linking type 2 diabetes and migraine is …

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Dementia
Knowledge and attitudes towards Alzheimer’s disease among adult residents in Jiulongpo, Chongqing, China: A cross-sectional survey

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview This research aimed to explore the awareness and perceptions regarding Alzheimer’s disease among …

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Dementia
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to explore the role of non-coding RNAs in the development …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenesis of Myasthenia Gravis Myasthenia Gravis (MG) is an autoimmune disorder characterized by weakness and …

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Functional neurological disorders
Dynamic electro-clinical features in Guanidinoacetate N-methyltransferase deficiency: A familial case series

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Clinical Presentation and Genetic Findings The study highlights the varied clinical presentations associated with Guanidinoacetate …

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Traumatic brain injury
Resting-State Brain Activity Changes and Their Genetic Correlates in Mild Traumatic Brain Injury

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Study Overview The investigation into resting-state brain activity alterations in individuals who have experienced mild …

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Functional neurological disorders
Seizures and Functional Deficits across Mendelian Disorders of Epigenetic Machinery: Differential Effects as a Function of Epigenetic Modifications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Understanding Mendelian Disorders Mendelian disorders are genetic conditions resulting from mutations in a single gene …

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Traumatic brain injury
Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

by myneuronews June 11, 2025

by myneuronews June 11, 2025

Study Overview This trial is meticulously designed to assess the effectiveness of a high-intensity, home-based …

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Traumatic brain injury
Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Pathophysiology of Post-concussion Syndrome Post-concussion syndrome (PCS) is a complex disorder that can arise following …

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Functional neurological disorders
Recognising and managing functional neurological disorder in the acute healthcare setting

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) represents a fascinating convergence of neurology and …

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Imported Familial Pulmonary and Cerebral Paragonimiasis in Korea: Cases and Literature Review from a Clinical Grand Round Conference
Study Overview The investigation into familial pulmonary and cerebral paragonimiasis in Korea highlights the challenges…
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model
Study Overview The research focuses on the role of GASDERMIN D in the context of…
Patient-reported outcomes and acceptability of suggestion and hypnosis-based therapy for functional neurological disorder within an NHS service
Patient-Reported Outcomes In examining the results derived from patient-reported outcomes, it is essential to highlight…
Language biomarker screening using AI: a transdiagnostic approach to brain
Language Biomarkers in AI Research Language biomarkers are pivotal in utilizing artificial intelligence for assessing…
Morning sleep inertia and its associated factors: Findings from a nationwide study
Understanding Sleep Inertia Sleep inertia refers to the temporary state of cognitive and physical impairment…

The Clinical Utility of a Novel Multimodal Assessment Battery for Acute Sport-Related Concussion
CONCLUSIONS: Symptom exacerbation during submaximal cardiovascular exercise and postural sway demonstrated clinical utility in detecting impairment within 7 days of a sport-related concussion, whereas event-related potentials and heart rate change during sustained handgrip did not.
Associations of Symptomatic Head Trauma/Concussion Diagnosis with Sleep-Related Outcomes in Children
IntroductionUsing National Health Interview Survey (NHIS) data from 2020 to 2022, we examined associations between a history of symptomatic head trauma/concussion diagnosis with sleep-related outcomes.MethodsGuardians of children aged 2-17 years answered survey questions indicating whether US children had prior symptomatic head trauma and/or a concussion diagnosis. Associations with symptomatic head trauma/concussion diagnosis and sleep outcomes […]
Synthetic Cannabinoid Use and Sports-Related Concussion Risk Among US Adolescents: Implications for School Health Screening and Prevention
CONCLUSIONS: SC use is associated with elevated sports-related concussion risk among adolescents.
Effectiveness of a Customized Rehabilitation Program for Adults With Post-Concussion Syndrome-A Randomized Controlled Crossover Trial
CONCLUSIONS: A shift away from symptom-based management to subgroup-informed customized rehabilitation may be key to advancing patient care and improving clinical outcomes for this population.
Visualizing and Quantifying Impact with Mechanochromic Sensing Paints Based on Self-Assembled Polydiacetylene-Silk Core-Shell Vesicles
Rapid detection and quantification of mechanical impact on surfaces is relevant for many fields, as it enables monitoring of material stresses and integrity or to assess the physiological effects of force on humans for concussions, gait, or blast dosimetry, among others. Accurate and quantitative detection of impact force, especially at high values (100-770 N), is […]