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Headaches
The P2Y13 receptor-mediated microglial morphological transformation through the p38MAPK signaling pathway contributes to central sensitization in a murine model of chronic migraine

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview The primary objective of this research was to investigate the role of the …

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Headaches
Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis

by myneuronews December 13, 2025

by myneuronews December 13, 2025

Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in …

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Traumatic brain injury
Educational Perspectives on Compassionate Concussion Care: A Scoping Review

by myneuronews December 12, 2025

by myneuronews December 12, 2025

Overview of Concussion Care Concussion care encompasses a multifaceted approach aimed at addressing the complexities …

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Traumatic brain injury
Efficacy and safety of L-oxiracetam on cognitive function in patients with traumatic brain injury: a multicentre, randomised, double-blind, phase 3 clinical trial

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This clinical trial investigated the effects of L-oxiracetam, a nootropic drug, on cognitive …

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Traumatic brain injury
Traumatic Brain Injury Across the Lifespan and in Conflict Zones

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Traumatic Brain Injury in Different Age Groups Traumatic brain injury (TBI) manifests distinctively across various …

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Traumatic brain injury
Traumatic Brain Injury Across the Lifespan and in Conflict Zones

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Understanding Traumatic Brain Injury Traumatic Brain Injury (TBI) occurs when an external force causes damage …

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Traumatic brain injury
Patterns, severity, and outcomes of traumatic brain injury in a regional referral hospital in Kenya: a retrospective cohort study

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Patterns of Traumatic Brain Injury Traumatic brain injury (TBI) is a significant public health challenge, …

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Headaches
Vestibular migraine vs. migraine only: integrated transcriptome-clinical profiling reveals shared inflammation and divergent metabolic pathways for targeted therapy

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This research investigates the similarities and differences between vestibular migraine and typical migraine …

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Traumatic brain injury
Glymphatic Dysfunction Reflects Post-Concussion Symptoms: Changes Within 1 Month and After 3 Months

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Study Overview The research explores the relationship between glymphatic dysfunction and post-concussion symptoms over a …

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Traumatic brain injury
Concussion in the Wild: Clinical Utility of Ambulatory Assessment of Symptoms and Everyday Exposures in Adolescents and Adults with Concussion

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Clinical Relevance The assessment of concussion severity and recovery in adolescents and adults holds significant …

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Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium
CONCLUSIONS: These findings collectively identify COL4A1 deficiency as a sensitizing factor for post-traumatic visual dysfunction and demonstrate that ASC-CCM exerts therapeutic effects by preserving retinal vascular structure and modulating inflammatory responses, positioning it as a promising candidate for treating TBI-related ocular neurovascular injury.
Hollow CuS nanocubes enhance serum metabolic profiles for rapid diagnosis and severity grading of traumatic brain injury
Traumatic brain injury (TBI) remains a significant global health burden and demands rapid, objective diagnostics that work outside imaging suites and intensive lab workflows. Here, we developed a copper sulfide (CuS) nanocube-assisted laser desorption/ionization mass spectrometry (LDI-MS) platform to acquire serum metabolic profiles (SMPs) with high sensitivity, low background in the low-m/z region, and excellent […]
Attention-Deficit/Hyperactivity Disorder Following Mild Traumatic Brain Injury in Children: A Retrospective Exploratory Study
Introduction This study examines whether attention-deficit/hyperactivity disorder (ADHD) can develop after traumatic brain injury in children. Overlapping acute symptoms can hinder early identification and diagnosis. We investigated whether demographic or acute clinical features are associated with the development of secondary ADHD (S-ADHD) following mild pediatric traumatic brain injury. Materials and methods We conducted a retrospective […]
Ultra-high contrast MRI: a new technique for recognizing secondary changes to the brain in patients with persistent symptoms following traumatic brain injury
CONCLUSION: The whiteout sign was strongly associated with being in the symptomatic group and is a potential biomarker for recognition of secondary changes to the brain in patients with persistent symptoms following TBI.
Transcranial direct current stimulation (tDCS) in conscious mice: a refined method for repetitive applications without restraint
Transcranial direct current stimulation (tDCS) for painless, non-invasive brain stimulation is a promising approach to enhance recovery after stroke. However, the precise molecular and cellular mechanisms underlying the effects of tDCS remain unclear, impeding its use in humans and necessitating research in experimental animals. Unlike humans, who receive tDCS fully awake, experimental models of tDCS […]