Tag:

metabolomics

Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Role of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …

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Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Insights Recent advancements in transcriptomic analysis have opened new avenues for understanding the …

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Dementia
Embracing the Modern Biochemistry of Brain Metabolism

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Understanding Brain Metabolism The brain is an extraordinarily energy-demanding organ, consuming approximately 20% of the …

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Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Metabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …

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Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Headaches
Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Metabolite Profile Changes Upon infection with the tick-borne encephalitis virus (TBEV), significant alterations occur in …

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Functional neurological disorders
The early-life gut microbiome in common pediatric diseases: roles and therapeutic implications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Role of Gut Microbiome in Pediatric Diseases The gut microbiome has emerged as a crucial …

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Functional neurological disorders
Perturbations in gut microbiota in autism spectrum disorder: a systematic review

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Gut Microbiota Alterations in Autism The gut microbiota consists of a diverse community of microorganisms …

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Functional neurological disorders
Environmental Levels of Bis(2-ethylhexyl)-tetrabromophthalate (TBPH) Cause Thyroid Toxicity and Early Carcinogenic Signals in Juvenile Fish

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Environmental Impact of TBPH Bis(2-ethylhexyl)-tetrabromophthalate (TBPH) is a brominated flame retardant commonly used in various …

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Development of chronic subdural haematoma from mild head injury: A case report and review of current Malaysian guidelines on traumatic brain injury
Delayed chronic subdural haematoma (cSDH) is a common but potentially serious complication following traumatic brain injury (TBI). Mild TBIs are commonly managed by primary care providers (PCPs), particularly in large, resource-limited settings such as Malaysia, where access to tertiary neurosurgical services may be delayed. Early identification of red-flag signs and symptoms and timely referrals are […]
Cognitive Proficiency after Traumatic Brain Injury in Children
Fifty-five children and adolescents with complicated mild-severe traumatic brain injury (TBI) completed the Wechsler Intelligence Scale for Children-Fifth Edition (WISC-V; Wechsler, 2014) within 1 to 12 months post-injury. Compared with demographically matched neurologically healthy controls, selected from the WISC-V standardization sample, participants with TBI demonstrated statistically significantly lower scores across WISC-V indices. The working memory, […]
Implementing Goal Attainment Scaling as a Person-Centered Measurement Tool to Direct Care and Evaluate Outcomes in Neurorehabilitation Settings
The purpose of this Special Communication is to describe barriers and facilitators to implementing goal attainment scaling (GAS) as a patient-centered measurement tool in neurorehabilitation settings. The experiences of three distinct neurorehabilitation settings that implemented GAS to enhance person-centered care and measure person-centered goal attainment are described: a neurorehabilitation service at an inpatient rehabilitation facility; […]
Construct Validity of the Tower of London Test: Generating a Construct Specification Equation Relating Problem Characteristics to Problem Difficulty in a Sample of Veterans with Mild Traumatic Brain Injury
The Tower of London (TOL) is a set of problem-solving tasks that are commonly used to measure cognition. No studies have developed construct specification equations (CSEs) to mathematically quantify how the characteristics of test problems relate to the difficulty of the problem in the TOL. We aimed to investigate the relationship between TOL problem characteristics […]
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury
Traumatic brain injury (TBI) is a serious clinical and social problem. Millions of TBI cases, that require hospitalization and consequently burden social security systems, are reported each year. Analysis of the time course of changes that occur in the brain after primary injury may help indicate therapeutic goals and treatment directions that will minimize severe […]