Tag:

neurodegenerative diseases

Traumatic brain injury
On media and messaging: fighting fear with facts as the science of chronic traumatic encephalopathy evolves

by myneuronews January 22, 2026

by myneuronews January 22, 2026

Understanding Chronic Traumatic Encephalopathy Chronic Traumatic Encephalopathy (CTE) is a progressive neurodegenerative disorder associated with …

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Dementia
Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia

by myneuronews January 21, 2026

by myneuronews January 21, 2026

Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia …

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Traumatic brain injury
Creatine Supplementation and the Brain: Have We Put the Cart Before the Horse?

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Creatine’s Role in Brain Health Creatine, a compound predominantly recognized for its benefits in muscle …

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Traumatic brain injury
A Novel NLRP3 Inhibitor AMS-17 Rescues Deficits in Long-Term Potentiation Following Mild Traumatic Brain Injury in Adult C57Bl/6 Mice

by myneuronews January 18, 2026

by myneuronews January 18, 2026

Study Overview The research focuses on investigating the effects of a novel NLRP3 inhibitor, AMS-17, …

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Dementia
Elevated cerebral oxygen extraction fraction in Parkinson’s disease correlates with motor impairment severity

by myneuronews January 18, 2026

by myneuronews January 18, 2026

Study Overview The investigation centers on the relationship between cerebral oxygen extraction and motor impairment …

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Traumatic brain injury
A Novel NLRP3 Inhibitor AMS-17 Rescues Deficits in Long-Term Potentiation Following Mild Traumatic Brain Injury in Adult C57Bl/6 Mice

by myneuronews January 18, 2026

by myneuronews January 18, 2026

Study Overview The research investigates the impact of a novel NLRP3 inhibitor, AMS-17, on cognitive …

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Functional neurological disorders
Conceptual frameworks and future directions for functional cognitive disorders in adults: a narrative review and integrative perspective

by myneuronews January 16, 2026

by myneuronews January 16, 2026

Functional Cognitive Disorders: An Overview Functional cognitive disorders represent a distinctive category within cognitive health, …

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Dementia
Preliminary comparison of FreeSurfer segmentation algorithms in the Wake Forest community‐based cohort and potential impact on ATN classification

by myneuronews January 13, 2026

by myneuronews January 13, 2026

Study Overview This research investigates the performance of various FreeSurfer segmentation algorithms within a community-based …

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Traumatic brain injury
Ultra-high contrast MRI of the brain and spinal cord using directly acquired and synthetic BipoLAr Inversion Recovery (BLAIR) images

by myneuronews January 12, 2026

by myneuronews January 12, 2026

Study Overview The research centered on enhancing the imaging capabilities of magnetic resonance imaging (MRI) …

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Dementia
Dysbiotic shift in the oral microbiota of patients with Alzheimer’s disease compared to their healthy life partners-a combinatorial approach and a paired study design

by myneuronews January 12, 2026

by myneuronews January 12, 2026

Dysbiotic Shift in Oral Microbiota The composition of the oral microbiota plays a crucial role …

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Extracellular Vesicle-Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. Extracellular vesicles (EVs) have emerged as promising biomarkers for neurodegeneration, owing to their accessibility in bodily fluids and dynamic molecular cargo, including microRNAs (miRNAs). The last decade has seen accumulating evidence for miRNA dysregulation in […]
P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury
The pathological basis underlying mild traumatic brain injury (mTBI)-induced long-term cognitive impairment is not fully understood. It is supposed that mTBI induces residential microglia activation rather than peripheral leukocyte infiltration to promote neuroinflammation, thus triggering myelin damage as well as cognitive impairment. The transformation of microglia towards a pro-inflammatory (M1 type) or anti-inflammatory (M2 type) […]
Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers
Mild traumatic brain injury can disrupt brain function and is associated with high morbidity and healthcare utilization. While many individuals recover from mild traumatic brain injury, a significant proportion experience long-term sequelae, collectively known as post-concussion syndrome. Symptoms of post-concussion syndrome include headache, dizziness, insomnia, cognitive processing difficulties and mental health disturbances. The disease burden […]
Differences in symptom duration and return to sport following sport-related concussion between French-speaking Canadian and European athletes
CONCLUSION: SRC recovery times differ significantly by geography and sex in French-speaking athletes. European athletes and males report shorter symptom and RTS durations.
Using Cervical Spine Proprioception and Vestibular/Oculomotor Assessments to Identify Return-to-Play Clearance Prognosis After Adolescent Concussion
CONCLUSIONS: Cervical spine proprioception and vestibular/oculomotor symptom provocation evaluated within 3 weeks of injury were not associated with RTP clearance time, potentially reflecting the complexity and multifaceted nature of RTP decisions.