Roles of Metformin and Pioglitazone in Regulating A1-like Astrocyte Activation in EAE Mice
Study Overview This investigation centers on the roles of two pharmacological agents, Metformin and Pioglitazone, in modulating the activation state […]
Purkinje cell-specific loss of Neurofascin and Ankyrin G causes disruption of axon initial segments, neurodegeneration, and cerebellar ataxia
Pathophysiological Mechanisms The pathophysiology underlying Purkinje cell-specific disruptions in neurofascin and ankyrin G reveals critical insights into the mechanisms that
Amyotrophic lateral sclerosis and chronic inflammatory demyelinating polyneuropathy coexistence in a patient with a C9orf72 variant: case report
Coexistence of Conditions Amyotrophic lateral sclerosis (ALS) and chronic inflammatory demyelinating polyneuropathy (CIDP) represent two distinct neurological disorders, yet their
Raloxifene Beyond Osteoporosis: Unlocking Neurorestoration Through Remyelination, Inflammatory Regulation, and Neuroimmune Modulation in CNS Pathologies
Raloxifene Mechanisms in Neurorestoration Raloxifene, a selective estrogen receptor modulator (SERM), is primarily known for its role in the treatment
Caffeic Acid Phenethyl Ester Enhanced the Klotho/SIRT1/Nrf2/HO-1 Axis to Protect Against Methylmercury-Induced ALS-Like Neurodegeneration
Study Overview The investigation focuses on the neuroprotective properties of caffeic acid phenethyl ester (CAPE) in the context of methylmercury
Relevance of serum neurofilament light chain determination as a biomarker in multiple sclerosis. Consensus of the Spanish Society of Neurology’s Study Group on Multiple Sclerosis and Related Neuroimmune Diseases
Relevance of Neurofilament Light Chain Neurofilament light chain (NfL) plays a crucial role in the assessment of neurodegenerative diseases, including
Reversal of Endogenous Bioelectrical Network Collapse in Advanced Childhood Cerebral X-Linked Adrenoleukodystrophy
Study Overview This study investigates the catastrophic decline of the endogenous bioelectrical network in patients with advanced forms of childhood
Enhanced therapeutic potential of paeoniflorin and vitamin B12 in intracerebropeduncle ethidium bromide-induced multiple sclerosis-like pathology
Study Overview The investigation centered on the therapeutic effects of two compounds, paeoniflorin and vitamin B12, in the context of
Persistent Bilateral [18F]THK5351 and Migrating Unilateral [18F]FDG Uptake in Anti-LGI1 Encephalitis
Study Overview This study investigates the neuroimaging characteristics and clinical presentation of anti-LGI1 encephalitis, with a focus on the distinctive
Blast Exposure Does Not Increase Blood Biomarkers of Neurodegeneration in Service Members and Veterans with and Without Uncomplicated Mild TBI
Study Overview The research investigates the relationship between blast exposure and neurodegeneration biomarkers in military personnel, specifically focusing on service