Tag:

neurodegenerative diseases

Traumatic brain injury
Integrated miRNA-proteomic profiling identifies chronic vesicle-trafficking and proteostasis disruptions after mild traumatic brain injury

by myneuronews January 28, 2026

by myneuronews January 28, 2026

Study Overview In the investigation of mild traumatic brain injury (mTBI), recent research has highlighted …

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Traumatic brain injury
Spinal Cord Tau and Protein Copathologies Associated With Chronic Traumatic Encephalopathy

by myneuronews January 26, 2026

by myneuronews January 26, 2026

Spinal Cord Pathology Insights The spinal cord plays a critical role in transmitting signals between …

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Dementia
Osmotin-derived 9-amino-acid peptide alleviates α-synuclein and MPTP-induced glial cell activation mediated neuroinflammation, protecting dopaminergic neurons in Parkinson’s disease mice brain

by myneuronews January 26, 2026

by myneuronews January 26, 2026

Study Overview The research investigates the potential therapeutic effects of a specific peptide derived from …

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Dementia
Preclinical Applications and Parameter Optimization of Low-Intensity Pulsed Ultrasound Therapy in Neurological Diseases: A Review

by myneuronews January 25, 2026

by myneuronews January 25, 2026

Study Overview The application of low-intensity pulsed ultrasound therapy (LIPUS) in treating neurological diseases has …

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Traumatic brain injury
On media and messaging: fighting fear with facts as the science of chronic traumatic encephalopathy evolves

by myneuronews January 22, 2026

by myneuronews January 22, 2026

Understanding Chronic Traumatic Encephalopathy Chronic Traumatic Encephalopathy (CTE) is a progressive neurodegenerative disorder associated with …

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Dementia
Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia

by myneuronews January 21, 2026

by myneuronews January 21, 2026

Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia …

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Traumatic brain injury
Creatine Supplementation and the Brain: Have We Put the Cart Before the Horse?

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Creatine’s Role in Brain Health Creatine, a compound predominantly recognized for its benefits in muscle …

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Traumatic brain injury
A Novel NLRP3 Inhibitor AMS-17 Rescues Deficits in Long-Term Potentiation Following Mild Traumatic Brain Injury in Adult C57Bl/6 Mice

by myneuronews January 18, 2026

by myneuronews January 18, 2026

Study Overview The research focuses on investigating the effects of a novel NLRP3 inhibitor, AMS-17, …

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Dementia
Elevated cerebral oxygen extraction fraction in Parkinson’s disease correlates with motor impairment severity

by myneuronews January 18, 2026

by myneuronews January 18, 2026

Study Overview The investigation centers on the relationship between cerebral oxygen extraction and motor impairment …

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Traumatic brain injury
A Novel NLRP3 Inhibitor AMS-17 Rescues Deficits in Long-Term Potentiation Following Mild Traumatic Brain Injury in Adult C57Bl/6 Mice

by myneuronews January 18, 2026

by myneuronews January 18, 2026

Study Overview The research investigates the impact of a novel NLRP3 inhibitor, AMS-17, on cognitive …

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Beyond the Concussion: Cerebral Venous Thrombosis Following Mild-to-Moderate Traumatic Brain Injury
Cerebral venous sinus thrombosis (CVST) accounts for a small proportion of strokes. Still, it carries meaningful clinical impact, classically linked to systemic prothrombotic conditions, hormonal influences, and severe traumatic brain injury (TBI). However, with advances in neuroimaging, it's now evident that trauma-related CVST (tCVST) can also complicate mild to moderate head injuries even in the […]
Network co-activation relates to executive function following pediatric traumatic brain injury
CONCLUSIONS: Findings illustrate the implications of disrupted downregulation of the default mode network by the SN following pediatric brain injury. They also demonstrate how disruption in functional connectivity may underlie poor executive function after childhood traumatic brain injury.
Symptom Exacerbation With Physical and Mental Activity and the Association With Clinical Outcomes After Sport-Related Concussion in Youth and Adults
CONCLUSIONS: These results demonstrate a potential physiological link between CSp and VOR deficits with self-reported symptom exacerbation during physical and mental activity, respectively. Future research is warranted to delineate the neurophysiological basis of these findings.
Updated Status of Physical Activity Research for People With Traumatic Brain Injury
CONCLUSIONS: The greater number of studies in Phases 3 and 4 suggest the field has evolved in 12 years. The lack of progress in Phase 5 provides opportunity for implementation science efforts. Recommendations for physical activity behavior research after msTBI are discussed.
Driving After Concussion: The Influence of Days Since Concussion on Simulated Driving Performance Recovery
CONCLUSIONS: Clinicians should consider recommendations that support limited driving during the acute stages (24-72 hours) of concussion followed by a gradual return to driving. A longitudinal study design in a larger sample is needed to better define driving performance recovery following concussion.