Tag:

neurodegenerative diseases

Traumatic brain injury
CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Microglial Function in Brain Injury Microglia, the primary immune cells of the central nervous system, …

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Dementia
Association Between Dietary Biotin Intake and Dementia Risk, Including Alzheimer’s Disease: A Prospective Study of 122 959 UK Biobank Participants

by myneuronews September 7, 2025

by myneuronews September 7, 2025

Background and Objectives The relationship between nutrition and cognitive health has garnered increasing attention in …

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Dementia
Enriched Environment Alleviate AD Pathological Progression by Reducing Microglia Complement Signaling in Aged Male APP/PS1 Mice

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Study Overview This research investigates the impact of enriched environments on Alzheimer’s disease (AD) progression …

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Functional neurological disorders
Functional neurological disorders: history and current situation

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Current Understanding of Functional Neurological Disorders Functional Neurological Disorders (FND) represent a complex interplay between …

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Traumatic brain injury
Quantitative video analysis of head acceleration events: a review

by myneuronews September 5, 2025

by myneuronews September 5, 2025

Study Overview This article presents a comprehensive review of the techniques and findings surrounding the …

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Dementia
Wealth, income and dementia in Germany: longitudinal findings from a representative survey among the oldest old

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Wealth and Income Disparities In Germany, wealth and income disparities significantly affect the elderly population, …

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Headaches
State-of-the-art preclinical techniques to study the impact of spreading depolarizations in awake rodents

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Overview of Spreading Depolarizations Spreading depolarizations (SDs) refer to a wave of electrical activity that …

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Traumatic brain injury
Chronic traumatic encephalopathy

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Pathophysiology of Chronic Traumatic Encephalopathy Chronic traumatic encephalopathy (CTE) is a neurodegenerative condition associated with …

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Dementia
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia

by myneuronews August 27, 2025

by myneuronews August 27, 2025

Study Overview The research presents an extensive analysis aimed at identifying potential biomarkers for frontotemporal …

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Dementia
Behavioral variant frontotemporal dementia as a model for understanding the cognitive and cerebral determinants of verbal creativity

by myneuronews August 23, 2025

by myneuronews August 23, 2025

Cognitive Profiles in Behavioral Variant Frontotemporal Dementia Behavioral variant frontotemporal dementia (bvFTD) presents distinct cognitive …

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Subtype shift, relapse rate and risk factors of frequent relapse in cluster headache: A multicenter, prospective, longitudinal observation
Study Overview The study focused on understanding the various types of cluster headaches, examining the…
Quercetin as a Multi-Target Natural Therapeutic in Aging-Related Diseases: Systemic Molecular and Cellular Mechanisms
Mechanisms of Action Quercetin, a flavonoid found abundantly in many fruits, vegetables, and beverages, exhibits…
Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
Understanding Suicidal Ideation Suicidal ideation refers to the thoughts or considerations of ending one’s own…
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Neurophysiological Insights The neurophysiological aspects of downhill mountain biking are critical to understanding how athletes…
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Study Overview This study investigates the morphological changes in microglia, the immune cells of the…

Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
More research is needed on suicidal ideation (SI) and self-harm (SH) following moderate-severe traumatic brain injury (TBI). Previous studies have shown limited, inconsistent associations with demographic and injury factors and relied on diagnosis-specific analyses of psychiatric factors. This cross-sectional survey included 387 individuals with moderate-severe TBI and examined correlations between SI, SH, and 35 other […]
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Background: Downhill mountain biking (MTB) is a high-velocity sport where riders are potentially exposed to impacts and concussion. Rapidly obtained Event-Related Potentials (ERPs) are a promising use of portable electroencephalography for clinical assessment of concussion-related neurological impairment at the point of care. However, the baseline neuroelectric profile of this specific sporting population is not fully […]
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Mild traumatic brain injury (mTBI) affects over 40 million people every year. One of its features includes the activation of microglia, the resident immune cells of the brain. Microglia assume different morphological states depending on their level of activation, such as surveilling ramified and activated hypertrophic, ameboid, and rod-like microglia. These states can be distinguished […]
Evaluation of Traumatic Brain Injury Severity Using the Abbreviated Injury Scale and the Injury Severity Score: A Retrospective Study in Two Eastern European Centers
Introduction: Traumatic brain injury (TBI) is a significant global public health issue, with long-term impacts on patients. This study examines the relationship between TBI severity, as measured by the Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS) at admission, and various sociodemographic, clinical, and injury-related factors. Methods: We conducted a retrospective analysis using […]
Non-invasive vagus nerve stimulation is associated with the reduction in persistent post-concussion symptoms: an observational study
INTRODUCTION: Traumatic brain injury (TBI) remains a major public health challenge, with mild TBI (mTBI) frequently resulting in persistent cognitive, affective, and somatic symptoms. Non-invasive vagus nerve stimulation (nVNS) has demonstrated potential in reducing neuroinflammation and promoting recovery in preclinical TBI models. This retrospective, observational study assessed the impact of adjunctive nVNS on postconcussive symptoms […]