Tag:

neurodegenerative diseases

Dementia
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217

by myneuronews November 17, 2025

by myneuronews November 17, 2025

Study Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits …

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Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice

by myneuronews November 15, 2025

by myneuronews November 15, 2025

Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …

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Traumatic brain injury
Microglia depletion improves hippocampal circuit function after mild traumatic brain injury in male mice

by myneuronews November 13, 2025

by myneuronews November 13, 2025

Study Overview The research aimed to investigate the effects of microglia depletion on hippocampal function …

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Traumatic brain injury
Diffusion Alterations at the Gray Matter/White Matter Boundary in Traumatic Encephalopathy Syndrome

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Diffusion Imaging Techniques Diffusion imaging techniques, particularly diffusion tensor imaging (DTI), have revolutionized the way …

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Functional neurological disorders
Increased salivary oxytocin correlates with lower self-reported interoceptive accuracy in functional neurological disorders

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Study Summary The study explores the relationship between salivary oxytocin levels and interoceptive accuracy in …

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Traumatic brain injury
Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis

by myneuronews November 8, 2025

by myneuronews November 8, 2025

Therapeutic Efficacy of VEGFC The treatment of traumatic brain injury (TBI) has been a significant …

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Functional neurological disorders
Modulating the sense of agency in functional neurological disorder using real-time fMRI neurofeedback: a proof-of-concept study

by myneuronews November 6, 2025

by myneuronews November 6, 2025

Modulating Agency in Functional Neurological Disorder Functional Neurological Disorder (FND) presents a unique challenge in …

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Dementia
Blue spaces and incident dementia: Differences by geospatial and historical contexts

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Impact of Blue Spaces on Cognitive Health Research into environmental influences on health has increasingly …

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Dementia
Cerebral amyloid angiopathy-related inflammation superimposed on alpha-synucleinopathies: a case report and literature review

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Study Overview This case report examines the complex relationship between cerebral amyloid angiopathy (CAA) and …

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Traumatic brain injury
Stabilizing microtubules increases acute cellular injury at high strain rates

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Study Overview This study investigates the relationship between the stabilization of microtubules and the susceptibility …

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Bioequivalence of Two Perampanel Oral Suspension Formulations in Healthy Subjects: A Randomized Crossover Study
Study Overview The investigation focused on comparing the bioequivalence of two formulations of perampanel oral…
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217
Study Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits…
Functional Neurological Disorder, Sleep, and Dreaming: A Large Online Questionnaire-Based Study
Background on Functional Neurological Disorder Functional Neurological Disorder (FND) encompasses a range of neurological symptoms…
Treatments for Functional Neurological Disorder: A Practical Guide for Program Development
Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) presents a unique challenge in both…
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
Study Overview The investigation focused on addressing the often-overlooked cognitive challenges faced by individuals who…

Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review
Very few studies exist examining the effects of mild traumatic brain injury (mTBI) in patients with obesity, which is notable given that mTBI represents ~80% of all recorded TBIs. Given that approximately 40% of US adults have an obese body mass index (with predictions that this proportion will continue to increase), it would be prudent […]
2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila
Traumatic brain injuries (TBIs) are a global source of hospitalization, long-term disability, and death. However, age, sex, and other demographics differ widely among patients and the variable characteristics of TBIs further obscure injury outcomes. Here, we used Drosophila melanogaster to assess the effects of mild, repeated TBI (multi-day, MD) compared to single, severe TBI (single-day, […]
C-FLAIR: Fluid-attenuated Inversion Recovery with Controlled Artifact Suppression in Brain MRI
Background The T2-weighted fluid-attenuated inversion recovery (FLAIR) sequence is part of the routine brain MRI protocol. In regions with strong inhomogeneities in the static magnetic (B(0)) field and/or the radiofrequency (RF) field, inadequate magnetization inversion results in artifacts that may mimic or obscure pathologic features. Purpose To reduce artifacts on FLAIR images by using an […]
Long intervals between repetitive concussions reduce risk of cognitive impairment and limit microglial activation, astrogliosis, and tauopathy in adolescent rats
Although previous studies have demonstrated the effects of concussions do not accumulate as the time interval between injuries increases, little is known about the relationship between this interval and the effects of repetitive concussions. The objective of this study is to explore the relationship between the time interval and changes in behavior and histology following […]
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
CONCLUSION/IMPLICATIONS: Through a multistep process that incorporated stakeholder input and a review of the empirical literature, we developed an evidence-informed intervention that fills a gap in current care for cognitive PPCSs. Future studies are needed to evaluate the efficacy of this intervention for individuals with chronic cognitive difficulties after mTBI. (PsycInfo Database Record (c) 2025 […]