Tag:

neurodegenerative diseases

Dementia
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Study Overview The research focuses on the role of GASDERMIN D in the context of …

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Dementia
Association between late-life air pollution exposure and medial temporal lobe atrophy in older women

by myneuronews January 2, 2026

by myneuronews January 2, 2026

Study Overview The research focuses on the potential relationship between exposure to air pollution in …

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Traumatic brain injury
Plasma biomarkers in chronic mild traumatic brain injury: A review

by myneuronews December 31, 2025

by myneuronews December 31, 2025

Biomarkers in Chronic Mild Traumatic Brain Injury Chronic mild traumatic brain injury (mTBI), commonly associated …

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Traumatic brain injury
The Evolving Role of Neuroimaging in Traumatic Brain Injury Research

by myneuronews December 26, 2025

by myneuronews December 26, 2025

Neuroimaging Techniques in TBI Neuroimaging has significantly transformed the landscape of traumatic brain injury (TBI) …

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Traumatic brain injury
Biomarkers

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Definition and Types Biomarkers are biological indicators that provide insights into the physiological or pathological …

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Traumatic brain injury
Basic Science and Pathogenesis

by myneuronews December 23, 2025

by myneuronews December 23, 2025

Understanding Pathogenesis Pathogenesis refers to the intricate mechanisms and processes through which diseases develop and …

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Dementia
Consideration of sex as a biological variable over the history of the 5xFAD Alzheimer’s Disease mouse model

by myneuronews December 17, 2025

by myneuronews December 17, 2025

Biological Considerations When investigating Alzheimer’s disease through animal models, particularly the 5xFAD mouse model, it …

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Traumatic brain injury
Ultra-high contrast MRI: a new technique for recognizing secondary changes to the brain in patients with persistent symptoms following traumatic brain injury

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Ultra-high Contrast MRI Technique The development of ultra-high contrast magnetic resonance imaging (MRI) represents a …

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Dementia
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective

by myneuronews December 13, 2025

by myneuronews December 13, 2025

Background on Genetic Frontotemporal Dementia Genetic frontotemporal dementia (FTD) is a group of neurodegenerative disorders …

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Traumatic brain injury
Traumatic Brain Injury Across the Lifespan and in Conflict Zones

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Understanding Traumatic Brain Injury Traumatic Brain Injury (TBI) occurs when an external force causes damage …

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Beyond the Concussion: Cerebral Venous Thrombosis Following Mild-to-Moderate Traumatic Brain Injury
Cerebral venous sinus thrombosis (CVST) accounts for a small proportion of strokes. Still, it carries meaningful clinical impact, classically linked to systemic prothrombotic conditions, hormonal influences, and severe traumatic brain injury (TBI). However, with advances in neuroimaging, it's now evident that trauma-related CVST (tCVST) can also complicate mild to moderate head injuries even in the […]
Network co-activation relates to executive function following pediatric traumatic brain injury
CONCLUSIONS: Findings illustrate the implications of disrupted downregulation of the default mode network by the SN following pediatric brain injury. They also demonstrate how disruption in functional connectivity may underlie poor executive function after childhood traumatic brain injury.
Symptom Exacerbation With Physical and Mental Activity and the Association With Clinical Outcomes After Sport-Related Concussion in Youth and Adults
CONCLUSIONS: These results demonstrate a potential physiological link between CSp and VOR deficits with self-reported symptom exacerbation during physical and mental activity, respectively. Future research is warranted to delineate the neurophysiological basis of these findings.
Updated Status of Physical Activity Research for People With Traumatic Brain Injury
CONCLUSIONS: The greater number of studies in Phases 3 and 4 suggest the field has evolved in 12 years. The lack of progress in Phase 5 provides opportunity for implementation science efforts. Recommendations for physical activity behavior research after msTBI are discussed.
Driving After Concussion: The Influence of Days Since Concussion on Simulated Driving Performance Recovery
CONCLUSIONS: Clinicians should consider recommendations that support limited driving during the acute stages (24-72 hours) of concussion followed by a gradual return to driving. A longitudinal study design in a larger sample is needed to better define driving performance recovery following concussion.