Tag:

neurodegenerative diseases

Dementia
Divergent and convergent TMEM106B pathology in murine models of neurodegeneration and human disease

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Pathological Roles of Tmem106b in Neurodegeneration The involvement of TMEM106B in neurodegenerative diseases is a …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes in Glial Scarring After a traumatic brain injury (TBI), the central nervous system …

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Traumatic brain injury
Letter: Mild Traumatic Brain Injury in Older Adults: Recovery Course and Insights on Early Predictors of Outcome

by myneuronews August 8, 2025

by myneuronews August 8, 2025

Recovery Patterns in Older Adults The recovery patterns following mild traumatic brain injury (mTBI) in …

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Dementia
Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis

by myneuronews August 7, 2025

by myneuronews August 7, 2025

Study Overview The research aimed to investigate the role of TDP-43 accumulation in the progression …

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Dementia
Exploring the mediating role of the plasma lipidome in the pathway from the gut microbiota to dementia: a Mendelian randomization study

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Study Overview This research investigates the intricate relationships between gut microbiota, plasma lipid profiles, and …

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Traumatic brain injury
Neurological Disorders and Clinical Progression in Boxers from the 20th Century: A Narrative Review

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Historical Context of Neurological Disorders The understanding of neurological disorders in Boxers has evolved significantly …

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Traumatic brain injury
A voice for Tom: an urgent call for more research into neurodegenerative disease and contact sport

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Neurodegenerative Disease and Contact Sports Neurodegenerative diseases represent a broad category of disorders characterized by …

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Traumatic brain injury
Cognitive-Communication Rehabilitation after Brain Injuries

by myneuronews July 28, 2025

by myneuronews July 28, 2025

Cognitive Communication Challenges Cognitive communication challenges arise when individuals experience difficulties in the processes that …

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Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

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Dementia
Embracing the Modern Biochemistry of Brain Metabolism

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Understanding Brain Metabolism The brain is an extraordinarily energy-demanding organ, consuming approximately 20% of the …

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Beyond the Concussion: Cerebral Venous Thrombosis Following Mild-to-Moderate Traumatic Brain Injury
Cerebral venous sinus thrombosis (CVST) accounts for a small proportion of strokes. Still, it carries meaningful clinical impact, classically linked to systemic prothrombotic conditions, hormonal influences, and severe traumatic brain injury (TBI). However, with advances in neuroimaging, it's now evident that trauma-related CVST (tCVST) can also complicate mild to moderate head injuries even in the […]
Network co-activation relates to executive function following pediatric traumatic brain injury
CONCLUSIONS: Findings illustrate the implications of disrupted downregulation of the default mode network by the SN following pediatric brain injury. They also demonstrate how disruption in functional connectivity may underlie poor executive function after childhood traumatic brain injury.
Monitoring the lateral ventricles in the presence of intracranial hemorrhage using automated dual segmentation
CONCLUSIONS: Automated dual segmentation of lateral ventricles and ICH using deep learning provides a reliable method to monitor TBI severity over time. The approach yielded clinically relevant information, including ICH and lateral ventricle volume changes across sessions. This approach offers an efficient analysis of CT images in ICH and particularly patients that develop IVH.
Quality of Life, Self-Reported Cognitive Difficulties, and Performance-Based Cognitive Problems in Multiple Sclerosis: What's Sleep Got to Do With It?
CONCLUSIONS: Poor sleep quality was not associated with performance-based cognitive functioning but was associated with greater self-reported cognitive difficulties. After accounting for disease progression, depression, and fatigue, poor sleep quality was significantly predictive of both Symptoms and Fatigue QoL.
Parent and Child Agreement of Brain Injury Perceptions Following Pediatric Concussion
CONCLUSIONS: Parent-child agreement regarding brain injury perceptions following a pediatric concussion was low (13%), reflecting the importance of assessing and then addressing parent and child perceptions individually in pediatric concussion management.