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neurodegenerative diseases

Functional neurological disorders
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Loss of CD98HC Phosphorylation The study demonstrates a significant finding regarding CD98HC, a glycoprotein that …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Microglia, the resident immune cells of the brain, play a crucial …

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Dementia
Deep-learning based multi-modal models for brain age, cognition and amyloid pathology prediction

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview This research aims to investigate the potential of deep learning techniques to simultaneously …

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Functional neurological disorders
A 2025 update on treatment strategies for the Alzheimer’s disease spectrum

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Current Treatment Approaches The treatment landscape for Alzheimer’s disease has evolved considerably, reflecting a multifaceted …

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Movement Disorders
circ_0005654 as a Sponge of the miR-588 Dual Pathway to Promote α-Synuclein Expression

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Study Overview The investigation centers around the long non-coding RNA circ_0005654 and its role as …

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Stroke
Research status and future perspectives of IL-27 in the treatment of stroke (Review)

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Current Understanding of IL-27 in Stroke Interleukin-27 (IL-27) is a cytokine that belongs to the …

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Functional neurological disorders
Advances in Diagnostic Approaches for Alzheimer’s Disease: From Biomarkers to Deep Learning Technology

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Advancements in Biomarker Identification Recent developments in the field of Alzheimer’s disease diagnostics have centered …

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Functional neurological disorders
Evidence of an unprecedented cytoplasmic function of DDX11, the Warsaw breakage syndrome DNA helicase, in regulating autophagy

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Cytoplasmic Role of DDX11 in Autophagy Recent research has unveiled a novel cytoplasmic function of …

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Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Background of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …

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Traumatic brain injury
Exercise plasma improves traumatic brain injury outcomes in mice

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Exercise-Induced Plasma Effects Physical activity is known to have numerous beneficial effects on health, particularly …

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Get Your Brain in the Game: Using Machine Learning to Predict Recovery Timelines Following Sports-Related Concussion
CONCLUSIONS: Overall, these findings support the use of machine learning models in concussion management - particularly with predicting recovery timelines.
Balance Impairments in Adolescents Post-Sports Concussion during Single and Dual Tasks
OBJECTIVE: This study aimed to explore changes in sway during single tasks and dual tasks in adolescents with and without sport concussion (SC).
Multiple factors contribute to pupillary light reflex: implications for screening of traumatic brain injury in military service members
CONCLUSIONS: When using PLR for screening of mTBI, an individual's age, history of prior mTBI, total lifetime TBI-related alterations in consciousness, sleep, and anxiety and depression symptoms should be considered when interpreting PLR metrics.
Neurobiology and Impact of Chronic Traumatic Encephalopathy in Athletes: A Focused Review
Recent reports have highlighted a troubling pattern of athletes exhibiting pronounced and unexplained behavioral changes. This phenomenon is often linked to chronic traumatic encephalopathy (CTE), a progressive neurodegenerative disorder associated with repeated head injuries in contact sports, and is characterized by the accumulation of abnormal tau protein in the brain. This paper provides a focused […]
Multivariate Base Rates of Standard- and Skyline-Cutoff Elevations on the Personality Assessment Inventory: Do They Distinguish Simulated from Genuine PTSD?
Multivariate base rates (MBR) of elevations are an emerging psychometric paradigm for enhanced interpretation of multiscale self-report data. The aims of this study were to calculate and compare MBR of scale/subscale elevations on the Personality Assessment Inventory (PAI) and determine the ability of MBR to differentiate between mood disorders (n = 524, k = 3), […]