Tag:

neuroinflammation

Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice

by myneuronews November 15, 2025

by myneuronews November 15, 2025

Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …

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Dementia
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Overview The research focused on understanding the intricate relationship between brain network connectivity and …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Biomarkers in cerebrospinal fluid analysis Cerebrospinal fluid (CSF) serves as a crucial medium for assessing …

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Traumatic brain injury
Microglia depletion improves hippocampal circuit function after mild traumatic brain injury in male mice

by myneuronews November 13, 2025

by myneuronews November 13, 2025

Study Overview The research aimed to investigate the effects of microglia depletion on hippocampal function …

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Traumatic brain injury
Bidirectional Interplay Between Traumatic Brain Injury and Cardiovascular Dysfunction in Athletes

by myneuronews November 13, 2025

by myneuronews November 13, 2025

Traumatic Brain Injury and Its Impacts on Cardiovascular Health Traumatic Brain Injury (TBI) is a …

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Traumatic brain injury
Diffusion Alterations at the Gray Matter/White Matter Boundary in Traumatic Encephalopathy Syndrome

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Diffusion Imaging Techniques Diffusion imaging techniques, particularly diffusion tensor imaging (DTI), have revolutionized the way …

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Traumatic brain injury
Psilocybin mitigates chronic behavioral and neurobiological alterations in a rat model of recurrent intimate partner violence-related brain injury

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Study Overview The study investigates the effects of psilocybin on chronic behavioral and neurobiological changes …

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Traumatic brain injury
A Modified Repetitive Closed Head Injury Model Inducing Persistent Neuroinflammation and Functional Deficits Without Extensive Cortical Tissue Destruction

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Study Overview This research explores the effects of repeated mild traumatic brain injuries (mTBIs) on …

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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

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Traumatic brain injury
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Study Overview This research examines the impact of engineered rotational acceleration on axonal injury in …

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Biomarkers for prediction of chronic traumatic encephalopathy-like pathology following repeated mild traumatic brain injury in rats are partially sex- and age-dependent
INTRODUCTION: Repeated mild traumatic brain injuries (rmTBIs) pose a high risk of developing chronic traumatic encephalopathy (CTE). Since this neurodegenerative disease is diagnosed only post-mortem, new biomarkers for early detection are needed. Although age at injury and biological sex are important factors in many brain pathologies, little is known about their relevance to rmTBI-induced CTE-like […]
Profiles of cold executive function performance among pediatric acquired brain injury
CONCLUSIONS: Distinct executive function profiles were observed across ABI subtypes, with PAS associated with the most pervasive impairments, TBI with selective deficits, and BT with targeted planning difficulties. These findings highlight the importance of tailored cognitive rehabilitation strategies based on ABI subtype.
Longitudinal neurocognitive outcomes in children with mild traumatic brain injury: An ABCD cohort analysis
CONCLUSIONS: The findings highlight the importance of accounting for pre-injury differences when evaluating neurocognitive outcomes following pediatric mTBI. Neurocognitive differences within a year post-injury may be more related to pre-existing individual factors rather than the injury itself, underscoring the need for a comprehensive approach in studying pediatric mTBI.
Fear Avoidance after Concussion Tool (FACT): patient-reported outcome measure development and content validation
CONCLUSION: The FACT has been developed to evaluate fear avoidance behaviour following concussion and has content validity. Future research should evaluate other measurement properties before implementation.
Spare the brain: female football players' perspectives of heading the ball, concussion knowledge and attitudes. A qualitative study
The aim of this study was to explore female football (soccer) players' perspectives of heading the ball, and perceived header injury risk. A qualitative approach was undertaken using reflexive thematic analysis. Focus groups and individual interviews were conducted using a semi-structured interview guide. Participants also completed a survey containing a validated concussion knowledge and attitudes […]