Tag:

neuroinflammation

Traumatic brain injury
A Modified Repetitive Closed Head Injury Model Inducing Persistent Neuroinflammation and Functional Deficits Without Extensive Cortical Tissue Destruction

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Study Overview This research explores the effects of repeated mild traumatic brain injuries (mTBIs) on …

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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

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Traumatic brain injury
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Study Overview This research examines the impact of engineered rotational acceleration on axonal injury in …

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Traumatic brain injury
A Comprehensive Approach to the Assessment and Management of Posttraumatic Headache

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Overview of Posttraumatic Headache Posttraumatic headache (PTH) is a prevalent and often debilitating disorder that …

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Traumatic brain injury
AQP4 in cerebrospinal fluid correlates with severity and prognosis in moderate to severe traumatic brain injury

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Background and Rationale Traumatic brain injury (TBI) is a significant public health concern, often resulting …

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Traumatic brain injury
The Effect of Mucuna pruriens on Depression-like Behavior Induced by a Mild Traumatic Brain Injury in Rats Is Associated with a Decrease in Brain Nitrite and Nitrate Levels

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Study Overview The research investigates the impact of Mucuna pruriens, a tropical legume known for …

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Traumatic brain injury
Post-Traumatic Epilepsy After Mild and Moderate Traumatic Brain Injury: A Narrative Review and Development of a Clinical Decision Tool

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Study Overview This review article examines the complex relationship between post-traumatic epilepsy (PTE) and mild …

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Dementia
Mitochondrial dysfunction, a new marker warning of neuropsychiatric disorder risk: evidence from genetics and epidemiology

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Mitochondrial Dysfunction and Neuropsychiatric Disorders Mitochondria, often referred to as the powerhouses of the cell, …

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Dementia
Apathy and cognitive decline as the first presentation of SLE-associated vascular dementia: a case report

by myneuronews October 20, 2025

by myneuronews October 20, 2025

Case Presentation A 45-year-old woman, previously healthy with no history of psychiatric or neurological disorders, …

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Traumatic brain injury
Understanding concussion in myalgic encephalomyelitis/chronic fatigue syndrome: Findings from the 2023 National Health Interview study

by myneuronews October 17, 2025

by myneuronews October 17, 2025

Concussion and Myalgic Encephalomyelitis Concussion is a type of traumatic brain injury that can have …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Mild traumatic brain injury and concussion and persisting post-concussion symptoms: new guidelines to support evidence-based assessment and management in Australia and Aotearoa New Zealand
No abstract
Examining Clinic-Based Healthcare Utilization Patterns in a Specialty Concussion Care Setting
CONCLUSIONS: Initiation of concussion care within one week of injury demonstrates comparable effectiveness regardless of exact timing, although early presentation favors single-provider management while later presentation requires enhanced interdisciplinary coordination.
Evaluating Diagnostic Strategies for Pediatric Traumatic Brain Injury: A Literature-Based Clinical Decision Analysis
CONCLUSIONS: Application of CDA to pediatric TBI demonstrates the potential value of biomarker integration in improving diagnostic accuracy and optimizing CT utilization. Biomarker-augmented strategies may enhance patient safety by reducing unnecessary radiation exposure, while maintaining sensitivity for clinically important injuries. Prospective validation and real-world implementation studies are needed to confirm clinical effectiveness and cost-effectiveness.
Isolated oculomotor nerve palsy following mild traumatic brain injury: diagnostic challenges and insights from High-Resolution MRI
CONCLUSIONS: High-resolution CE-MRI proves instrumental in diagnosing isolated ONP in mild TBI patients, even without conventional radiological indicators. Early imaging and intervention may improve recovery outcomes. This study underscores the significance of including CE-MRI in evaluation protocols for ONP. It highlights the importance of further research to unravel the underlying pathophysiology and optimize therapeutic approaches […]
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) can result in persistent cognitive deficits (particularly in attention, processing speed, and working memory), even years after the injury. The majority of behavioural studies have focussed on averaged cognitive performance scores, such as average reaction time or accuracy scores after mTBI. However, less is understood about how mTBI affects intraindividual […]