Tag:

neuroinflammation

Dementia
Decoding amyloid beta clearance systems at inner blood-retina barrier using three-dimensional ex vivo retinal imaging in Alzheimer’s disease

by myneuronews October 5, 2025

by myneuronews October 5, 2025

Amyloid Beta Clearance Mechanisms Amyloid beta (Aβ) is a peptide that plays a crucial role …

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Dementia
Differences in inflammatory markers, mitochondrial function, and synaptic proteins in male and female Alzheimer’s disease post mortem brains

by myneuronews October 1, 2025

by myneuronews October 1, 2025

Inflammatory Markers Comparison Research into Alzheimer’s disease has increasingly highlighted the significance of inflammation in …

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Dementia
Maintenance of neuronal TDP-43 expression requires axonal lysosome transport

by myneuronews September 19, 2025

by myneuronews September 19, 2025

Study Overview The investigation centered on understanding the critical role of TDP-43, a protein associated …

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Traumatic brain injury
Cumulative and Contextual Effects of Low-Level Blast Exposure on Cognitive Function in Military Personnel: Interactions With PTSD and Mild TBI

by myneuronews September 19, 2025

by myneuronews September 19, 2025

Cumulative effects of blast exposure The cumulative impact of low-level blast exposure on cognitive abilities …

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Traumatic brain injury
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats

by myneuronews September 13, 2025

by myneuronews September 13, 2025

Study Overview This study investigates the morphological changes in microglia, the immune cells of the …

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Traumatic brain injury
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region

by myneuronews September 12, 2025

by myneuronews September 12, 2025

Study Overview The research in question investigates the effects of Spautin-1, a compound known for …

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Dementia
Estimated Glucose Disposal Rate and Risk of Stroke and Dementia in Nondiabetics: A UK Biobank Prospective Cohort Study

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview The investigation centered around the relationship between glucose disposal rate and the risk …

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Traumatic brain injury
CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Microglial Function in Brain Injury Microglia, the primary immune cells of the central nervous system, …

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Dementia
Boston University Alzheimer’s Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer’s disease and related dementias

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Research Objectives The primary aim of the Boston University Alzheimer’s Disease Research Center Clinical Core …

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Traumatic brain injury
Progressive lifespan modifications in the corpus callosum following a single concussion in juvenile male mice monitored by diffusion MRI

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Study Overview The investigation aimed to explore the long-term impacts of a single concussion on …

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Long-term neurological and psychiatric complications and vocational outcome after cerebral venous sinus thrombosis
Patient Characteristics The demographic profile of patients who experience cerebral venous sinus thrombosis (CVST) provides…
Reply to “Clarifying the Moderating Role of Socioeconomic Status on Amyloid-Related Gray Matter Atrophy”
Study Overview This study addresses the complex interactions between socioeconomic status (SES) and the neurobiological…
A Scoping Review of Measures Used to Assess Stress-Related Motor Dysfunction in Functional Movement Disorder
Assessment Methods Overview Assessing stress-related motor dysfunction in individuals with functional movement disorder (FMD) encompasses…
Hysterical disorders in patients with hematological diseases
Prevalence of Hysterical Disorders in Hematological Patients The intersection of hematological diseases and hysterical disorders…
Indigenizing paediatric concussion injury prevention
Indigenous Perspectives on Concussion Understanding concussion within Indigenous communities requires a deep appreciation of cultural…

IL6 in Combination with Either NfL, NTproBNP, or GFAP to Safely Discharge Children with Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) in children is a public health concern resulting in one of the main causes of pediatric emergency department (PED) visits. However, the acute care of mTBI patients remains challenging due to the limited use of specific and safe diagnostic tools. The objective of the study was to evaluate the performance […]
What traditional neuropsychological assessment got wrong about mild traumatic brain injury. III: the added value of advanced neuroimaging
CONCLUSIONS: Characterizations from traditional neuropsychological measures as independent tests indicating no lasting sequelae from mTBI, especially after three-months post-injury from mTBI need to be viewed within the context of what advanced neuroimaging can demonstrate. Future directions involving the integration of advanced neuroimaging developments applicable to the mTBI patient are reviewed, especially when integrated with neuropsychological […]
Preparing for Potential Health and Safety Risks at the Olympic Games: Scoping Review
CONCLUSIONS: A critical summary of studies of illness, injury, and terrorist attacks at previous Olympic Games is important for injury and terrorism prevention at major sporting events such as the Olympic Games. Surveillance methods require improvements in surveillance technology, data sharing, and privacy protection.
Infographic. Keep an eye on vision after concussion-screening tool and procedure for the two most common concussion-related vision disorders: convergence insufficiency and accommodative insufficiency
No abstract
Plumbagin Alleviates Mild Traumatic Brain Injury-Induced Obsessive-Compulsive Disorder in Mice by Inhibiting nNOS and Augmenting Cortico-Striatal Serotonin Levels
Increased nitric oxide activity in the medial prefrontal cortex (mPFC) and striatum plays a key role in the pathogenesis of obsessive-compulsive disorder (OCD) by lowering serotonin contents and triggering neurodegeneration. Since molecular docking analysis revealed plumbagin as a potent inhibitor of neuronal nitric oxide synthase (nNOS) enzyme, this study aims to investigate the ameliorative potential […]