Microglia and neuroinflammation: An in-depth analysis from functional diversity to disease mechanisms
Microglial Functional Diversity Microglia are the primary immune cells of the central nervous system (CNS), playing a crucial role in […]
Smoldering neuroinflammation in progressive multiple sclerosis: mechanisms, imaging biomarkers, and therapeutic opportunities
Smoldering Neuroinflammation Mechanisms In progressive multiple sclerosis (MS), smoldering neuroinflammation is a crucial factor that contributes to disease advancement despite
Corrigendum to “Ginsenoside Rg1 alleviates cognitive impairment in vascular dementia by modulating Adcy1/Kdr-mediated cholinergic synapse and PI3K-AKT pathway” [Phytomedicine, 143 (2025) 156882]
Study Overview This research investigates the role of Ginsenoside Rg1, a principal bioactive compound derived from ginseng, in addressing cognitive
Isoschaftoside improves white matter injury via TREM2-mediated phagocytosis and anti-inflammatory effects
Mechanisms of Isoshaftoside Action Isoshaftoside is a glycoside derived from various plant sources, notably known for its potential therapeutic effects
Regulatory T cells as drivers of CNS remyelination: neuro-immune cross-talk and comparative insights from mammalian and zebrafish models
Regulatory T Cells in CNS Repair Regulatory T cells (Tregs) play a pivotal role in maintaining immune homeostasis within the
Modulatory effects of traditional Chinese medicine and derived active metabolites on autoimmune-inflammatory signaling pathways in multiple sclerosis: a narrative review
Modulatory Effects of Traditional Chinese Medicine Traditional Chinese Medicine (TCM) encompasses a variety of therapeutic practices that have evolved over
Whole-blood point-of-care glial fibrillary acidic protein and ubiquitin C-terminal hydrolase L1 biomarkers after traumatic brain injury in the US: a prospective diagnostic prediction of intracranial injury on head CT
Biomarker Significance in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant public health challenge, often resulting in long-term
Hinokitiol Promotes Neural Repair After Spinal Cord Injury by Reprogramming Microglial Inflammatory and Redox Responses
Neural Repair Mechanisms Neural repair following spinal cord injury (SCI) is a complex biological process that involves multiple cellular and
Polyunsaturated Fatty Acid Supplementation in Multiple Sclerosis Management: A Scoping Review
Study Overview The exploration into the role of polyunsaturated fatty acids (PUFAs) in managing multiple sclerosis (MS) has gained increasing
Schwann Cell Activity in the Multiple Sclerosis Microenvironment
Schwann Cell Functions in Multiple Sclerosis In the context of multiple sclerosis (MS), Schwann cells play a multifaceted role that
Schwann Cell Activity in the Multiple Sclerosis Microenvironment Read Post »