Kynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …
Tag:
neuroinflammation
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Traumatic brain injury
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury
by myneuronewsby myneuronewsStudy Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive …
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Traumatic brain injury
Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review
by myneuronewsby myneuronewsClinical Outcomes in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant challenge in …
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Traumatic brain injury
2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila
by myneuronewsby myneuronewsStudy Overview The investigation centers around understanding how innate immune signaling influences the outcomes of …
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Traumatic brain injury
Long intervals between repetitive concussions reduce risk of cognitive impairment and limit microglial activation, astrogliosis, and tauopathy in adolescent rats
by myneuronewsby myneuronewsImpact of Concussion Intervals on Cognitive Outcomes Research indicates that the timing between concussive events …
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Traumatic brain injury
Biomarkers for prediction of chronic traumatic encephalopathy-like pathology following repeated mild traumatic brain injury in rats are partially sex- and age-dependent
by myneuronewsby myneuronewsStudy Overview The research embarked on an investigation into the long-term effects of repeated mild …
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Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice
by myneuronewsby myneuronewsImpact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …
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Dementia
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum
by myneuronewsby myneuronewsStudy Overview The research focused on understanding the intricate relationship between brain network connectivity and …
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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
by myneuronewsby myneuronewsBiomarkers in cerebrospinal fluid analysis Cerebrospinal fluid (CSF) serves as a crucial medium for assessing …
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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
by myneuronewsby myneuronewsMetabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …