Tag:

neuroinflammation

Dementia
Cognitive Function, Physical Activity, and Sweat Cytokines in Older Adults With Dementia

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Cognitive Function Assessment Assessing cognitive function in older adults, especially those with dementia, involves various …

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Traumatic brain injury
Inhibition of microglia priming by NLRP3 reduces the impact of early life stress and mild TBI

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Study Overview The objective of the research was to investigate how inhibiting the activation of …

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Traumatic brain injury
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Study Overview The study aimed to explore the genetic underpinnings of Alzheimer’s disease (AD) through …

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Traumatic brain injury
Examining the potential of psilocybin and 5-MeO-DMT as therapeutics for traumatic brain injury

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Therapeutic Mechanisms of Psilocybin and 5-MeO-DMT Psilocybin and 5-MeO-DMT, both naturally occurring psychedelic compounds, have …

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Traumatic brain injury
Brain biomarker profiles vary with semi-synthetic and grain-based diets in healthy and mTBI mice

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Brain Biomarker Profiles Recent studies have highlighted the importance of brain biomarker profiles in understanding …

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Functional neurological disorders
Identifying pyroptosis- and inflammation-related genes in spinal cord injury based on bioinformatics analysis

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Gene Identification Methods To identify genes that play a role in pyroptosis and inflammation following …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP The role of ALOX5AP (Arachidonate 5-Lipoxygenase Activating Protein) in the pathogenesis …

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Traumatic brain injury
A one year longitudinal study of cortical myelination changes following pediatric mild traumatic brain injury

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Cortical Myelination Changes Cortical myelination refers to the formation and maturation of myelin sheaths around …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein) plays a pivotal role in the pathophysiology …

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Functional neurological disorders
Epileptic seizure biophysics: the role of local voltage difference

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Understanding Seizure Mechanisms Seizures are complex neurological events that arise from abnormal electrical activity in …

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Immunological Tolerance Induced by Nanoliposome with Autoantigenie Peptide and Artesunate to Inhibit Complement and Remodel Immune Balance for Multiple Sclerosis Treatment
Study Overview The research investigates the potential of using nanoliposomes as a delivery system for…
Neuromuscular Blockade Efficacy in High Elastance ARDS: Signal or Statistical Noise?
Study Overview This research investigates the efficacy of neuromuscular blockade in patients exhibiting high elastance…
The Association of a Polygenic Lifespan Score With the Risk of Common Age-Related Diseases and Mortality
Study Overview The research investigates the relationship between a polygenic lifespan score—derived from multiple genetic…
Comparing patient-reported symptoms and structured clinician documentation in electronic health records
Symptom Reporting Comparisons Research into the differences between symptoms reported by patients and those documented…
Clinical Characterization and Long-Term Outcome in Children and Adults With Anti-AMPA Receptor Encephalitis
Clinical Presentation The clinical presentation of anti-AMPA receptor encephalitis is characterized by a diverse array…

Cognitive Workload During a Sustained Visual Attention Task in Middle-Aged and Older Adults With Persistent Symptoms After a Mild Traumatic Brain Injury
BackgroundIndividuals with prolonged symptoms after a mild traumatic brain injury (mTBI) report requiring more effort to complete complex and sustained activities. However, the relationship between cognitive workload and patient-reported symptoms is unclear.ObjectiveTo compare the cognitive workload between middle-aged and older adults with persistent symptoms after mTBI and controls during a sustained visual attention task and […]
Sex differences in temperature rhythm disruption after traumatic brain injury
Circadian rhythms are a natural endogenous process that regulates many bodily functions including body temperature and are linked to overall health. Disruptions in circadian rhythms have far reaching effects on systems vulnerable to traumatic brain injury (TBI), including sleep, neuroendocrine and immune function, and mental health. Whether TBI affects temperature rhythms differently in females and […]
Language impairment is associated with faster progression in progressive supranuclear palsy-Richardson syndrome
INTRODUCTION: Cognitive impairment is common but often overlooked due to motor symptoms in progressive supranuclear palsy-Richardson syndrome (PSP-RS). This study investigates whether cognitive deficits predict disease progression in PSP-RS.
Bedside Ultrasonographic Measurement of Optic Nerve Sheath Diameter for Assessing Increased Intracranial Pressure: An Observational Study
Background Traumatic brain injury (TBI) is a leading cause of disability and mortality, particularly in resource-limited settings where advanced neuromonitoring tools are often unavailable. Elevated intracranial pressure (ICP) is a serious and potentially life-threatening complication of TBI. Traditional methods for monitoring ICP are invasive, expensive, and require specialized expertise. Ultrasonographic measurement of the optic nerve […]
Early-Life Mild Traumatic Brain Injury Alters Neurodevelopment and Behavior in Mice
Approximately 280 children per 100,000 experience closed-head injuries each year, with over 80% being mild in severity. While most children with mild injuries do not require admission to a hospital and recover well over time, some children experience persistent behavioral and cognitive abnormalities that continue into adolescence. Mild traumatic brain injury (mTBI) during early life […]