Tag:

neuroinflammation

Dementia
Examination of age- and sex-related changes in protein expression within the hippocampus and prefrontal cortex during withdrawal from a subchronic history of binge-drinking in C57BL/6J mice

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Study Overview This study investigates the impact of binge-drinking behavior on protein expression in specific …

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Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging findings in Wilson’s disease reveal significant alterations in brain …

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Traumatic brain injury
Microglial depletion and repopulation differentially modulate sleep and inflammation in a mouse model of traumatic brain injury

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Study Overview This research investigates the complex relationship between microglial cells, sleep patterns, and inflammation …

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Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Findings The study employs an integrated transcriptomic approach, utilizing high-throughput RNA sequencing to …

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Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Insights Recent advancements in transcriptomic analysis have opened new avenues for understanding the …

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Traumatic brain injury
Neurobiology and Impact of Chronic Traumatic Encephalopathy in Athletes: A Focused Review

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Neurobiological Mechanisms Chronic Traumatic Encephalopathy (CTE) is a progressive neurodegenerative disease primarily associated with repeated …

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Functional neurological disorders
Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson’s Disease

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Integrated Transcriptomic Approaches The integration of transcriptomic approaches offers a powerful way to glean insights …

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Functional neurological disorders
Rhynchophylline Reverses Obesity in High-Fat Diet-Induced Obese Rats by Regulating the Inflammatory Cascade and Blocking 3‑hydroxy-3-methylglutaryl Coenzyme A Reductase

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Effects of Rhynchophylline on Obesity In recent studies examining the effects of rhynchophylline on obesity, …

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Dementia
Cognitive Function, Physical Activity, and Sweat Cytokines in Older Adults With Dementia

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Cognitive Function Assessment Assessing cognitive function in older adults, especially those with dementia, involves various …

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Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience
Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that…
Collaborative Community Support for People Impacted by Dementia: A Social Return on Investment Analysis
Study Overview This research focuses on understanding the impact of a community-based support program designed…
A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Cognitive Fatigue in Pediatric Populations Cognitive fatigue is a significant concern in pediatric populations, particularly…
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
Study Overview This research investigates the connection between gut-derived neurotoxin trimethylamine N-oxide (TMAO) and the…
ENIGMA’s advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Study Overview The study focuses on enhancing the accuracy of brain lesion parcellation, a crucial…

A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Acquired Brain Injuries (ABIs) cause long-term disruption to young individuals' development. Persistent cognitive fatigue is a commonly reported sequela following pediatric ABI. Currently, there are no evidence-based interventions targeting cognitive fatigue post-ABI amongst pediatric patients. The current systematic review and meta-analysis aimed to review research on the efficacy of pharmacological and non-pharmacological interventions for cognitive […]
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
CONCLUSION: Serum TMAO levels were significantly elevated in PTSD patients comorbid with TBI and were closely associated with PTSD severity. Furthermore, TMAO may aid in the early identification of high-risk, severe PTSD patients following TBI, thus helping to optimize intervention strategies.
ENIGMA's advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Cortical parcellation is a critical step in several neuroimaging pipelines, yet even in high quality images without pathology, errors are common. For patients with moderate to severe traumatic brain injury (ms-TBI), typical parcellation errors can be exacerbated by focal pathology impacting cortical regions. Careful visual quality checking (QC) of parcellation images of ms-TBI patients should […]
Knowledge and attitudes of concussion and chronic traumatic encephalopathy amongst a sample of non-professional rugby players
CONCLUSIONS: Non-professional rugby players are generally knowledgeable about concussion. However, some gaps in their knowledge relating to coma and the course of symptoms of concussion were identified. Unsafe attitudes, particularly among school players, need to be addressed. Non-professional rugby players are interested in further education about CTE.
Multi-modal proton and sodium MRI for outcome prediction in mild traumatic brain injury
CONCLUSIONS: We identified independent, dynamic, metabolic and ionic changes, with choline and creatine from spectroscopy fulfilling the most criteria for a clinical biomarker.