Tag:

neuroinflammation

Traumatic brain injury
Impact of prior exposures on biomarkers of blast during military tactical training

by myneuronews May 28, 2025

by myneuronews May 28, 2025

Study Overview This investigation aims to examine how prior exposures, particularly to blast injuries, influence …

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Functional neurological disorders
Deficits of Alzheimer’s Disease Neuropsychological Architecture Correlate with Specific Exosomal mRNA Expression: Evidence of a Continuum?

by myneuronews May 28, 2025

by myneuronews May 28, 2025

Neuropsychological Deficits in Alzheimer’s Disease Alzheimer’s disease (AD) is often characterized by a progressive decline …

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Functional neurological disorders
Immune inflammatory regulation in Anti-NMDAR encephalitis: insights from transcriptome analysis

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Immune Mechanisms in Anti-NMDAR Encephalitis Anti-NMDAR encephalitis is characterized by the presence of antibodies that …

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Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Background of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …

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Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Material and Methods The study on fully biodegradable dendrimers as novel nanodrugs targeting amyloid-β-induced neurotoxicity …

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Stroke
Lipidomic profiling of the cerebrospinal fluid in moyamoya angiopathy patients

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Lipidomic profiling in moyamoya angiopathy Lipidomic profiling involves the comprehensive analysis of lipids within biological …

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Traumatic brain injury
Exercise plasma improves traumatic brain injury outcomes in mice

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Effects of Exercise Plasma on Brain Injury Research has shown that exercise can have profound …

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Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Biodegradable Dendrimers: A Novel Approach Dendrimers are highly branched molecules that can be customized at …

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Functional neurological disorders
Aggressive and Refractory Attack of AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder Treated With Ravulizumab: A Case Report

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Clinical Presentation and Diagnosis In this case report, the patient presented with symptoms characteristic of …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Subcutaneous Botulinum Toxin Type-A Injections for the Treatment of Central Neuropathic Pain in a Patient With Multiple Sclerosis – A Case Report
Study Overview This case report examines the application of subcutaneous injections of botulinum toxin type…
Homozygous COQ9 mutation: a new cause of potentially treatable hereditary spastic paraplegia
Study Overview The research investigates the role of homozygous mutations in the COQ9 gene as…
Trends in acute care of cerebrovascular events- a joinpoint analysis with German hospital data from 2000 to 2021
Cerebrovascular Event Trends The prevalence and incidence of cerebrovascular events, commonly known as strokes, have…
Gepants in Primary Care: A Targeted Approach to Acute and Preventive Treatment of Migraine
Gepants Mechanism of Action Gepants are a novel class of oral medications specifically designed to…
Targeting cognitive aging with curcumin supplementation: A systematic review and meta-analysis
Study Overview The systematic review and meta-analysis centered on curcumin supplementation aimed to investigate its…

Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods
Military service members (SMs) and veterans who have sustained one or more concussions during their service have significantly higher rates of persistent depressive symptoms and suicidality compared to non-injured peers. Despite over 500,000 SMs who have sustained concussions, there are currently no Level I evidence-based treatments for improving depressive symptoms associated with concussion. Accelerated intermittent […]
Dietary Intake of n-3 Polyunsaturated Fatty Acids Prior to a Mild Traumatic Brain Injury Demonstrates a Dose-Response Effect for Neuroprotective Benefits in Male C57BL/6 Mice
CONCLUSIONS: Overall, these results show that dietary n-3 PUFA confer neuroprotective benefits in mice resulting in significantly improved functional outcomes. This work is relevant to clinical practitioners, athletes, and the general population who aim to support their neurological health through dietary or supplementary n-3 PUFA.
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared to Orthopedic Injury
CONCLUSIONS AND RELEVANCE: BDNF DNAm appears to differ in children with TBI vs OI, particularly in the acute period. BDNF DNAm differences may reflect early biological responses that are specific to TBI.
Multimodal Magnetic Resonance Imaging with Mild Repetitive Head Injury in Awake Rats: Modeling the Human Experience and Clinical Condition
Mild repetitive head injury is a serious health problem with long-term negative consequences. Changes in brain neurobiology were assessed with MRI in a model of head injury designed to reflect the human experience. Rats were maintained on a reverse light-dark cycle and head impacted daily at 24 h intervals over three days while fully awake […]
Microstructural Damage Progression in the Pia-Arachnoid Complex
Traumatic brain injury is a leading cause of death and disability worldwide, with mild traumatic brain injury comprising the majority of cases. The pia-arachnoid complex (PAC), located at the brain-skull interface, plays a critical role in brain mechanics during head impacts, yet its response to mechanical loading is understudied. This study investigates the progression of […]